PRUNE2

gene product
A214N16.3, bA214N16.3, BMCC1, BNIPXL, C9orf65, KIAA0367
The protein encoded by this gene belongs to the B-cell CLL/lymphoma 2 and adenovirus E1B 19 kDa interacting family, whose members play roles in many cellular processes including apotosis, cell transformation, and synaptic function. Several functions for this protein have been demonstrated including suppression of Ras homolog family member A activity, which results in reduced stress fiber formation and suppression of oncogenic cellular transformation. A high molecular weight isoform of this protein has also been shown to colocalize with Adaptor protein complex 2, beta-Adaptin and endodermal markers, suggesting an involvement in post-endocytic trafficking. In prostate cancer cells, this gene acts as a tumor suppressor and its expression is regulated by prostate cancer antigen 3, a non-protein coding gene on the opposite DNA strand in an intron of this gene. Prostate cancer antigen 3 regulates levels of this gene through formation of a double-stranded RNA that undergoes adenosine deaminase actin on RNA-dependent adenosine-to-inosine RNA editing. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
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113 antibodies from 28 providers.

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Antibody
Proteintech Group
1 antibody
Abnova Corporation
5 antibodies
antibodies-online
29 antibodies
Novus Biologicals
4 antibodies
Invitrogen Antibodies
4 antibodies
OriGene
2 antibodies
NovoPro Bioscience Inc.
1 antibody
Atlas Antibodies
2 antibodies
Arigo
2 antibodies
Cusabio Biotech Co., Ltd
2 antibodies
Antibodies.com
1 antibody
Bioworld Technology, Inc
1 antibody
LifeSpan BioSciences, Inc.
7 antibodies
Biorbyt
8 antibodies
Aviva Systems Biology
2 antibodies
Acris Antibodies GmbH
2 antibodies
Everest Biotech
1 antibody
NSJ Bioreagents
1 antibody
GeneTex
1 antibody
Affinity Biosciences
1 antibody
Creative Diagnostics
1 antibody
ProSci
1 antibody
St John's Laboratory
1 antibody
United States Biological
25 antibodies
MyBioSource
2 antibodies
MilliporeSigma / Merck KGaA
2 antibodies
Abbexa
3 antibodies
Leading Biology
1 antibody