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- Antibody Data
- Antigen structure
- References [15]
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- Product number
- 23829-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- IREB2 antibody
- Antibody type
- Polyclonal
- Description
- IREB2 antibody (Cat. #23829-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Salvia miltiorrhiza Bge. processed with porcine cardiac blood inhibited GLRX5-mediated ferroptosis alleviating cerebral ischemia-reperfusion injury.
Heterogeneous ferroptosis susceptibility of macrophages caused by focal iron overload exacerbates rheumatoid arthritis.
Targeting Ferroptosis Promotes Functional Recovery by Mitigating White Matter Injury Following Acute Carbon Monoxide Poisoning.
1,4-dihydroxy quininib activates ferroptosis pathways in metastatic uveal melanoma and reveals a novel prognostic biomarker signature.
Anti-aging Factor GRSF1 Attenuates Cerebral Ischemia-Reperfusion Injury in Mice by Inhibiting GPX4-Mediated Ferroptosis.
KLF14 regulates the growth of hepatocellular carcinoma cells via its modulation of iron homeostasis through the repression of iron-responsive element-binding protein 2.
Phenazine derivatives attenuate the stemness of breast cancer cells through triggering ferroptosis.
Activation of vitamin D receptor inhibits Tau phosphorylation is associated with reduction of iron accumulation in APP/PS1 transgenic mice.
Identification of dynamic RNA-binding proteins uncovers a Cpeb4-controlled regulatory cascade during pathological cell growth of cardiomyocytes.
DHA exhibits synergistic therapeutic efficacy with cisplatin to induce ferroptosis in pancreatic ductal adenocarcinoma via modulation of iron metabolism.
The deubiquitinase OTUD1 enhances iron transport and potentiates host antitumor immunity.
Iron deposition-induced ferroptosis in alveolar type II cells promotes the development of pulmonary fibrosis.
Iron regulatory protein 2 is required for artemether -mediated anti-hepatic fibrosis through ferroptosis pathway.
MiR-935 Promotes Clear Cell Renal Cell Carcinoma Migration and Invasion by Targeting IREB2.
Iron Transport from Ferrous Bisglycinate and Ferrous Sulfate in DMT1-Knockout Human Intestinal Caco-2 Cells.
Zhou S, Wang Z, Wang T, Peng C, Zhang J, Liu C, Xu J, Zhang Y, Zhang L, Luo L, Yan X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155622
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155622
Heterogeneous ferroptosis susceptibility of macrophages caused by focal iron overload exacerbates rheumatoid arthritis.
Liu Y, Luo X, Chen Y, Dang J, Zeng D, Guo X, Weng W, Zhao J, Shi X, Chen J, Dong B, Zhong S, Ren J, Li Y, Wang J, Zhang J, Sun J, Xu H, Lu Y, Brand D, Zheng SG, Pan Y
Redox biology 2024 Feb;69:103008
Redox biology 2024 Feb;69:103008
Targeting Ferroptosis Promotes Functional Recovery by Mitigating White Matter Injury Following Acute Carbon Monoxide Poisoning.
Wang S, Xiong B, Tian Y, Hu Q, Jiang X, Zhang J, Chen L, Wang R, Li M, Zhou X, Zhang T, Ge H, Yu A
Molecular neurobiology 2024 Feb;61(2):1157-1174
Molecular neurobiology 2024 Feb;61(2):1157-1174
1,4-dihydroxy quininib activates ferroptosis pathways in metastatic uveal melanoma and reveals a novel prognostic biomarker signature.
Tonelotto V, Costa-Garcia M, O'Reilly E, Smith KF, Slater K, Dillon ET, Pendino M, Higgins C, Sist P, Bosch R, Passamonti S, Piulats JM, Villanueva A, Tramer F, Vanella L, Carey M, Kennedy BN
Cell death discovery 2024 Feb 10;10(1):70
Cell death discovery 2024 Feb 10;10(1):70
Anti-aging Factor GRSF1 Attenuates Cerebral Ischemia-Reperfusion Injury in Mice by Inhibiting GPX4-Mediated Ferroptosis.
Li Y, Shen Q, Huang L, Li B, Zhang Y, Wang W, Zhao B, Gao W
Molecular neurobiology 2024 Apr;61(4):2151-2164
Molecular neurobiology 2024 Apr;61(4):2151-2164
KLF14 regulates the growth of hepatocellular carcinoma cells via its modulation of iron homeostasis through the repression of iron-responsive element-binding protein 2.
Zhou H, Chen J, Fan M, Cai H, Dong Y, Qiu Y, Zhuang Q, Lei Z, Li M, Ding X, Yan P, Lin A, Zheng S, Yan Q
Journal of experimental & clinical cancer research : CR 2023 Jan 5;42(1):5
Journal of experimental & clinical cancer research : CR 2023 Jan 5;42(1):5
Phenazine derivatives attenuate the stemness of breast cancer cells through triggering ferroptosis.
Yang Y, Lu Y, Zhang C, Guo Q, Zhang W, Wang T, Xia Z, Liu J, Cheng X, Xi T, Jiang F, Zheng L
Cellular and molecular life sciences : CMLS 2022 Jun 11;79(7):360
Cellular and molecular life sciences : CMLS 2022 Jun 11;79(7):360
Activation of vitamin D receptor inhibits Tau phosphorylation is associated with reduction of iron accumulation in APP/PS1 transgenic mice.
Wu TY, Zhao LX, Zhang YH, Fan YG
Neurochemistry international 2022 Feb;153:105260
Neurochemistry international 2022 Feb;153:105260
Identification of dynamic RNA-binding proteins uncovers a Cpeb4-controlled regulatory cascade during pathological cell growth of cardiomyocytes.
Riechert E, Kmietczyk V, Stein F, Schwarzl T, Sekaran T, Jürgensen L, Kamuf-Schenk V, Varma E, Hofmann C, Rettel M, Gür K, Ölschläger J, Kühl F, Martin J, Ramirez-Pedraza M, Fernandez M, Doroudgar S, Méndez R, Katus HA, Hentze MW, Völkers M
Cell reports 2021 May 11;35(6):109100
Cell reports 2021 May 11;35(6):109100
DHA exhibits synergistic therapeutic efficacy with cisplatin to induce ferroptosis in pancreatic ductal adenocarcinoma via modulation of iron metabolism.
Du J, Wang X, Li Y, Ren X, Zhou Y, Hu W, Zhou C, Jing Q, Yang C, Wang L, Li H, Fang L, Zhou Y, Tong X, Wang Y
Cell death & disease 2021 Jul 15;12(7):705
Cell death & disease 2021 Jul 15;12(7):705
The deubiquitinase OTUD1 enhances iron transport and potentiates host antitumor immunity.
Song J, Liu T, Yin Y, Zhao W, Lin Z, Yin Y, Lu D, You F
EMBO reports 2021 Feb 3;22(2):e51162
EMBO reports 2021 Feb 3;22(2):e51162
Iron deposition-induced ferroptosis in alveolar type II cells promotes the development of pulmonary fibrosis.
Cheng H, Feng D, Li X, Gao L, Tang S, Liu W, Wu X, Yue S, Li C, Luo Z
Biochimica et biophysica acta. Molecular basis of disease 2021 Dec 1;1867(12):166204
Biochimica et biophysica acta. Molecular basis of disease 2021 Dec 1;1867(12):166204
Iron regulatory protein 2 is required for artemether -mediated anti-hepatic fibrosis through ferroptosis pathway.
Li Y, Jin C, Shen M, Wang Z, Tan S, Chen A, Wang S, Shao J, Zhang F, Zhang Z, Zheng S
Free radical biology & medicine 2020 Nov 20;160:845-859
Free radical biology & medicine 2020 Nov 20;160:845-859
MiR-935 Promotes Clear Cell Renal Cell Carcinoma Migration and Invasion by Targeting IREB2.
Liu F, Chen Y, Chen B, Liu C, Xing J
Cancer management and research 2019;11:10891-10900
Cancer management and research 2019;11:10891-10900
Iron Transport from Ferrous Bisglycinate and Ferrous Sulfate in DMT1-Knockout Human Intestinal Caco-2 Cells.
Yu X, Chen L, Ding H, Zhao Y, Feng J
Nutrients 2019 Feb 26;11(3)
Nutrients 2019 Feb 26;11(3)
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- A549 cells were subjected to SDS PAGE followed by western blot with 23829-1-AP( IREB2 Antibody) at dilution of 1:1000
- Other comments
- WB
