Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [347]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunoprecipitation [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 12422-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12422-1-AP, RRID:AB_2162467
- Product name
- Alix antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Alix antibody (Cat. #12422-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references M2 macrophage-derived exosomes mitigate acute inflammation following ischemic stroke.
Hypoxia‑induced exosomal CAMTA1 promotes radio‑resistance in MDA‑MB‑231 cells by regulating NRG1 to mediate M2 macrophage polarization.
Exosomes derived from Bcl-2-engineered iPSC-cardiomyocytes mitigate aortic valve calcification and inhibit cardiomyocyte apoptosis.
Plasma tau-species positive neuron-derived extracellular vesicles in progressive supranuclear palsy.
Spatiotemporal Sequential Delivery of Chidamide Regulates Macrophage Reprogramming in Lymphoma Microenvironment Through HDACs-STAT3 Pathway.
Membrane-Confined CRISPR-Cas12a Activation via Split Activator for Wash-Free Detection of Tumor-Specific Extracellular Vesicles.
Pyroptosis-Inducing Engineered Microparticles for Cancer Immunotherapy.
Fibroblast-derived exosomes induce macrophage pyroptosis to mediate orthodontic bone remodeling through the mtDNA/NLRP3 axis.
UBQLN1 Inhibition reduces MASH progression through downregulating SIKE/p38 MAPK pathway in hepatocyte.
Inhibition of ESCRT-III activates alternative pathways for protein degradation and secretion.
Titanium-guided neutrophil dynamics for inflammation resolution and tissue integration.
Selective peptide-guided transcytosis enhances extracellular vesicle-mediated siRNA delivery across the blood-brain barrier.
Tumor-Derived CDC37 Inhibits Antigen Cross-Presentation in Dendritic Cells and Impairs Anti-Tumor Immunity in Breast Cancer.
Investigating the Potential Role of Capsaicin in Facilitating the Spread of Coxsackievirus B3 via Extracellular Vesicles.
Proteomic analysis revealed the potential usefulness of faecal extracellular vesicles in colorectal cancer diagnosis.
Peroxiredoxin 1 mediates bleomycin-induced acute lung injury in mice via macrophage NOD1/NF-κB axis.
COPD airway epithelial cells-derived extracellular vesicles contribute to endothelial dysfunction and atherosclerosis via the miR-141-3p/PDCD4 axis.
Enhanced release of ciliary extracellular vesicles suppresses cell migration and promotes cell aggregation.
Targeted inhibition of PARP-1 in pulmonary epithelial cells and macrophages via SPA-functionalized microparticles attenuates sepsis-induced lung injury.
Small extracellular vesicles derived from lipotoxic hepatocytes transport FASN to promote hepatic stellate cell activation.
Spatiotemporally controlled pretargeted azide-functionalized M1 macrophage-derived exosome-based (68)Ga/(177)Lu theranostic system for PET imaging and targeted radiotherapy in breast cancer.
Ascites circRNA ASCOR Drives Platinum Resistance of High-Grade Serous Ovarian Cancer by Facilitating RPA1 Nuclear Translocation.
Extracellular vesicle-associated lncRNA LYPLAL1-DT mediates endothelial-cancer cell communication, promoting small cell lung cancer progression.
Proteomic Landscape of Small Extracellular Vesicles Derived From Gastric Juice and Identified TFF2 as a Specific Biomarker.
Hyperammonemia increases the release of pathological extracellular vesicles from monocytes by impairing lysosomal function and autophagy through the TNFα-cAMP-PKA-LC3 pathway.
Silk fibroin-collagen hydrogel loaded with IGF1-CESCs attenuates intervertebral disk degeneration by accelerating annulus fibrosus healing in rats.
Comprehensive exome profiling identifies ARHGEF12 mutation as a driver in gastric cancer with ovarian metastasis.
The Effects of M2 Macrophages-Derived Exosomes on Urethral Fibrosis and Stricture in Scar Formation.
Curcumin-primed milk-derived extracellular vesicles remodel hair follicle microenvironment for the treatment of androgenetic alopecia.
Hypoxia-induced immunosuppression in uveal melanoma is mediated by CD63(+) exosomes delivering lactate to reprogram immune cells.
Protecting and rejuvenating ageing skin by regulating endogenous hyaluronan metabolism using adipose-derived stem cell-secreted siRNAs.
STING inhibits LINE-1 retrotransposition through sorting ORF1p to lysosomes for degradation.
Multidimensional Engineering of Extracellular Vesicles for Targeted Delivery and Microglial Reprograming in Spinal Cord Injury Repair.
Exosomes derived from human umbilical cord mesenchymal stem cells attenuate hepatic ischaemia-reperfusion injury via the let-7i-5p/Faslg axis.
Polystyrene nanoplastics-induced methuosis in brain microvascular endothelial cells: Rescue via ESCRT membrane repair system.
Failure of efficient cardiac proteostatic adaptations to chronic cAMP-stress is associated with accelerated heart aging.
The exosomal miRNA-3184-3p derived from highly metastatic melanoma cells promotes metastatic competency via the positive feedback loop of NLK/Wnt/S100A11.
Aerobic Exercise Attenuates Autophagy-Lysosomal Flux Deficits via β2-AR-Mediated ESCRT-III Subunit CHMP4B in Mice With Human MAPT P301L.
Urinary extracellular vesicle RNAs as novel biomarkers for diagnosis and prognosis of lupus nephritis.
Flemiphilippinin A induces paraptosis in lung cancer cells via c-Myc-driven endoplasmic reticulum stress and CHOP-mediated mitochondrial dysfunction.
POSTN-Mediated Interplay of M1 Polarized Macrophage with Tendon-Derived Stem Cells to Drive Traumatic Heterotopic Ossification Formation through PTK7/ATK Signaling?
Pak4-mediated crosstalk between necroptotic macrophages and tendon stem/progenitor cells contributes to traumatic heterotopic ossification formation.
Generation of Cellular Biofactories for Scalable Production of Surface-Engineered Extracellular Vesicles via CRISPR Genome Editing.
Microneedles combining delivery of hUMSC-derived exosomes and EGCG mitigate UV-induced skin damage.
Efficient Scaling up EV-AAVs Production via Cellular Nanoporation for Familial Hypercholesterolaemia Therapy.
VesicleVoyager: In Vivo Selection of Surface Displayed Proteins That Direct Extracellular Vesicles to Tissue-Specific Targets.
Gastric cancer-derived exosomal miR-196a-5p remodels the pre-metastatic niche for peritoneal dissemination.
Succinic Acid-Induced Macrophage Endocytosis Promotes Extracellular Vesicle-Based Integrin Beta1 Transfer Accelerating Fibroblast Activation and Sepsis-Associated Pulmonary Fibrosis.
ER stress induced extracellular vesicles secretion from macrophages promotes calcium oxalate crystals formation in kidney.
Umbilical Cord Mesenchymal Stromal Cell-Derived Extracellular Vesicles Transfer CD59 to Astrocytes to Alleviate Complement-Dependent Cytotoxicity.
Histone lactylation-induced GLI3 activation drives macrophage M1 polarization and exosomal SERPINE1 release in abdominal aortic aneurysm progression.
Exosomes enriched with miR-31-3p from keratinocytes under oxidative stress promote vitiligo progression by destructing melanocytes and activating CD8(+) T cells.
Extracellular vesicles engineered to directly target encephalomyocarditis virus ameliorates multi-organ viremia in a lethal infection model.
Unusual chaetoglobosins and a new type of ferroptosis inducer from an endophytic fungus Chaetomium sp. UJN-EF006.
Tumor-derived exosomal CCT6A serves as a matchmaker introducing chemokines to tumor-associated macrophages in pancreatic ductal adenocarcinoma.
Breast cancer stem cell-derived exosomal lnc-PDGFD induces fibroblast-niche formation and promotes lung metastasis.
Decorin-mediated dermal papilla cell-derived exosomes regulate hair follicle growth and development through miR-129-2-3p/SMAD3/TGF-β axis.
Extracellular vesicle-packaged PKM2 from endometriotic stromal cells promotes endometrial collagen I deposition by inhibiting autophagy in endometriosis.
Bone marrow mesenchymal stem cell exosomes improve fracture union via remodeling metabolism in nonunion rat model.
Radiotherapy-derived engineered stem cell exosomes improve anti-glioma immunotherapy by promoting the formation of tertiary lymphoid structure and improve the release of type I interferon.
Platelet Membrane and miR-181a-5p Doubly Optimized Nanovesicles Enhance Cardiac Repair Post-Myocardial Infarction through Macrophage Polarization.
Endocrine-exocrine miR-503-322 drives aging-associated pancreatitis via targeting MKNK1 in acinar cells.
Psychological stress-induced ALKBH5 deficiency promotes tumour innervation and pancreatic cancer via extracellular vesicle transfer of RNA.
Mechanism of Tau protein incorporation into exosomes via cooperative recognition of KFERQ-like motifs by LAMP2A and HSP70.
In Vivo Reprogramming of Tissue-Derived Extracellular Vesicles for Treating Chronic Tissue Injury Through Metabolic Engineering.
Extracellular Vesicles from Peripheral Blood Mononuclear Cells of Hyperammonemic Rats Induce Neuroinflammation in Hippocampus, Impairing Memory and Learning in Normal Rats.
VesicleVoyager: In vivo selection of surface displayed proteins that direct extracellular vesicles to tissue-specific targets.
A Novel Modulator of Resistance for Oxaliplatin-Based Therapy for Colorectal Cancer: The ESCRT Family Member VPS4A.
DDX5 super-enhancer promotes vasculogenic mimicry formation and metastasis in nasopharyngeal carcinoma by enhancing ADAM10 transcription.
Tβ4-Engineered ADSC Extracellular Vesicles Rescue Cell Senescence Through Separable Microneedle Patches for Diabetic Wound Healing.
Glucocorticoid-Induced Muscle Satellite Cell-Derived Extracellular Vesicles Mediate Skeletal Muscle Atrophy via the miR-335-5p/MAPK11/iNOS Pathway.
Extracellular vesicle-enriched secretome of adipose-derived stem cells upregulates clusterin to alleviate doxorubicin-induced apoptosis in cardiomyocytes.
Chronic sleep deprivation induces plasma exosome-derived miR-150-5p downregulation as a novel mechanism involved in Parkinson's disease progression by targeting DCLK1.
USP5 inhibition via bone marrow-targeted engineered exosomes for myeloproliferative neoplasms therapy.
Serum small extracellular vesicles-derived BST2 as a biomarker for papillary thyroid microcarcinoma promotes lymph node metastasis.
Harnessing Tumor Cell-Derived Exosomes for Immune Rejection Management in Corneal Transplantation.
Diagnostic role of circulating long non-coding RNA LINC00312 in patients with non-small cell lung cancer: a retrospective study.
Concurrent Detection of Protein and miRNA at the Single Extracellular Vesicle Level Using a Digital Dual CRISPR-Cas Assay.
In vivo evidence of increased vascular endothelial growth factor in patients with major depressive disorder.
MFGE8 induces anti-PD-1 therapy resistance by promoting extracellular vesicle sorting of PD-L1.
α-Synuclein Promotes the Expression and Release of Neurofilament Light Chain from Oligodendrocytes in a Murine Model: Implication for Multiple System Atrophy?
3D-cultured DFAT spheroid-derived exosomes promote aged wound healing via modulation of the NF-κB/Serpine1 pathway.
A panel of miRNAs in serum extracellular vesicles serves as novel diagnostic biomarkers for MASLD.
The brown fat-enriched exosomal miR-206-3p attenuates hepatic lipogenesis by decreasing pentose phosphate pathway.
Mesenchymal stem cell-derived small extracellular vesicles-loaded GelMA microspheres enhance diabetic wound healing by promoting M2 macrophage polarization through p38 MAPK inhibition.
Recruiting T-cells toward the brain for enhanced glioblastoma chemo-immunotherapy efficacy by co-delivery of cytokines and temozolomide via ultrasound-gated redox-responsive extracellular vesicles.
Macrophage-derived exosomal miR-466i-5p and miR-365-2-5p stimulated by BMP-2 promote osteogenesis.
Tumor-secreted factors induce aberrant accumulation of vitamin A-enriched lipid droplets in the liver.
Rab27a-mediated exosome secretion facilitates classical swine fever virus release and immune evasion.
Atosiban-conjugated 3WJ-pRNA nanoparticles delivering GAS1-enhanced extracellular vesicles: targeting the decidua to combat recurrent miscarriage.
Liver-breast communication of adipocyte-oriented exosomes drives primary mammary cancer progression.
Extracellular vesicles from obese visceral adipose promote pancreatic cancer development and resistance to immune checkpoint blockade therapy.
tsRNA-10105-enriched migrasomes mediate hepatocellular carcinoma immunosuppressive microenvironment by inducing M2 Macrophage polarization.
Synergistic chemoimmunotherapy using pirarubicin-loaded tumor-derived extracellular vesicles for triple-negative breast cancer (TNBC).
An engineered M2 macrophage-derived exosomes-loaded electrospun biomimetic periosteum promotes cell recruitment, immunoregulation, and angiogenesis in bone regeneration.
Anti-Her2 CAR-NK92 Cells and Their Exosomes: Generation, Characterization, and Selective Cytotoxicity Against Her2-Positive Tumor Cells.
Arachidonic acid triggers spermidine synthase secretion from primary tumor to induce skeletal muscle weakness upon irradiation.
The Redox Enzyme Thioredoxin Is Increased in Plasma Extracellular Vesicles From Endurance-Trained Females in Response to Acute Exercise.
Hypoxia-induced exosomal circNRIP1 activates cancer-associated fibroblasts to promote esophageal squamous cell carcinoma migration and invasion.
Comparisons of miRNA profiles of exosomes derived from human iPSCs, ADSCs, and BMSCs and effects on chondrocyte function.
Development of an Effective Isolation Method for Plasma Extracellular Vesicles Excluding Lipoproteins by Precipitation With Polyethylene Glycol.
Physically engineered extracellular vesicles targeted delivering miR-21-5p to promote renoprotection after renal ischemia-reperfusion injury.
Exosome-loaded tannic acid-thioctic acid hydrogel enhances wound healing in coagulation disorders.
Proteomic Analysis of Human Follicular Fluid-Derived Exosomes Reveals That Insufficient Folliculogenesis in Aging Women is Associated With Infertility.
tsRNA-12391-Modified Adipose Mesenchymal Stem Cell-Derived Exosomes Mitigate Cartilage Degeneration in Osteoarthritis by Enhancing Mitophagy.
Dendritic Cell Derived-Extracellular Vesicles Engineered to Express Interleukin-12 and Anti-CTLA-4 on Their Surface for Combinational Cancer Immunotherapy.
LIMA1 O-GlcNAcylation Promotes Hepatic Lipid Deposition through Inducing β-catenin-Regulated FASn Expression in Metabolic Dysfunction-Associated Steatotic Liver Disease.
Classical swine fever virus recruits ALIX and ESCRT-III to facilitate viral budding.
YWHAE affects proliferation, migration and apoptosis of colorectal cancer by regulating extracellular vesicles secretion and Wnt/β-catenin signaling pathway.
The assembly of RAB22A/TMEM33/RTN4 initiates a secretory ER-phagy pathway.
Microglia-targeting nanosystems that cooperatively deliver Chinese herbal ingredients alleviate behavioral and cognitive deficits in Alzheimer's disease model mice.
In vitro study on the promotion of osteogenic differentiation by mitochondrial-derived vesicles through activation of inflammation and reprogramming of metabolic pathways.
Microvesicles carrying EV71 virions cross BBB through endocytic pathway to induce brain injury.
Injectable ECM-mimetic dynamic hydrogels abolish ferroptosis-induced post-discectomy herniation through delivering nucleus pulposus progenitor cell-derived exosomes.
A methodological primer of extracellular vesicles isolation and characterization via different techniques.
Inhibition of triple-negative breast cancer growth via delphinidin-mediated suppression of the JAK2/STAT3/PD-L1 pathway.
Exosomal SLC16A1-AS1-induced M2 macrophages polarization facilitates hepatocellular carcinoma progression.
Investigating Neuroplasticity Changes Reflected by BDNF Levels in Astrocyte-Derived Extracellular Vesicles in Patients with Depression.
Human umbilical cord mesenchymal stem cells derived-exosomes alleviate LPS-induced cervical inflammation and epithelial-mesenchymal transition.
Glioblastoma-derived exosomes promote lipid accumulation and induce ferroptosis in dendritic cells via the NRF2/GPX4 pathway.
Bone marrow mesenchymal stem cell-derived exosomes improve cancer drug delivery in human cell lines and a mouse osteosarcoma model.
ECM1 and ANXA1 in urinary extracellular vesicles serve as biomarkers for breast cancer.
Engineered nanovesicles from activated neutrophils with enriched bactericidal proteins have molecular debridement ability and promote infectious wound healing.
Exosomes Derived from Meningitic Escherichia coli-Infected Brain Microvascular Endothelial Cells Facilitate Astrocyte Activation.
Bone marrow stromal and anterior cruciate ligament remnant cell co-culture-derived extracellular vesicles promote cell activity in both cell types.
Effect of lyophilized exosomes derived from umbilical cord stem cells on chronic anterior cruciate ligament cell injury.
GRP75 triggers white adipose tissue browning to promote cancer-associated cachexia.
Novel Insights Into DLAT's Role in Alzheimer's Disease-Related Copper Toxicity Through Microglial Exosome Dynamics.
Exosomes Derived from Rejuvenated Stem Cells Inactivate NLRP3 Inflammasome and Pyroptosis of Nucleus Pulposus Cells via the Transfer of Antioxidants.
Exosomal Src from hypoxic vascular smooth muscle cells exacerbates ischemic brain injury by promoting M1 microglial polarization.
Small RNAs in plasma extracellular vesicles define biomarkers of premanifest changes in Huntington's disease.
Proteomic Profiling of Serum Extracellular Vesicles Identifies Diagnostic Signatures and Therapeutic Targets in Breast Cancer.
Neuroserpin and Extracellular Vesicles in Ischemic Stroke: Partners in Neuroprotection?
Glycoengineered extracellular vesicles released from antibacterial hydrogel facilitate diabetic wound healing by promoting angiogenesis.
α-Synuclein species in plasma neuron-derived extracellular vesicles as biomarkers for iRBD.
Barcoding of small extracellular vesicles with CRISPR-gRNA enables comprehensive, subpopulation-specific analysis of their biogenesis and release regulators.
Exosomal lncRNA Mir100hg derived from cancer stem cells enhance glycolysis and promote metastasis of melanoma through miR-16-5p and miR-23a-3p.
Exposure to micron-grade silica particles triggers pulmonary fibrosis through cell-to-cell delivery of exosomal miR-107.
circCDK13-loaded small extracellular vesicles accelerate healing in preclinical diabetic wound models.
Irradiated microparticles suppress prostate cancer by tumor microenvironment reprogramming and ferroptosis.
ANXA3-Rich Exosomes Derived from Tumor-Associated Macrophages Regulate Ferroptosis and Lymphatic Metastasis of Laryngeal Squamous Cell Carcinoma.
Novel lncRNA Gm33149 modulates metastatic heterogeneity in melanoma by regulating the miR-5623-3p/Wnt axis via exosomal transfer.
Rab3a attenuates spinal cord injury by mediating vesicle release.
ALIX and TSG101 are essential for cellular entry and replication of two porcine alphacoronaviruses.
The Combined Anti-Aging Effect of Hydrolyzed Collagen Oligopeptides and Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells on Human Skin Fibroblasts.
A technique for repeated blood and cerebrospinal fluid sampling from individual rats over time without the need for repeated anesthesia.
Isolation and characterization of small extracellular vesicles from murine primary mammary tumor.
Neutrophil-derived nanovesicles deliver IL-37 to mitigate renal ischemia-reperfusion injury via endothelial cell targeting.
Plasma exosomes from patients with active thyroid-associated orbitopathy induce inflammation and fibrosis in orbital fibroblasts.
M2 macrophage-derived exosomes promote angiogenesis and improve cardiac function after myocardial infarction.
Activation of the Wnt/β-catenin signalling pathway enhances exosome production by hucMSCs and improves their capability to promote diabetic wound healing.
Macrophage Phenotype Induced by Circulating Small Extracellular Vesicles from Women with Endometriosis.
Magnetic Particle Imaging Reveals that Iron-Labeled Extracellular Vesicles Accumulate in Brains of Mice with Metastases.
Functionally improved mesenchymal stem cells via nanosecond pulsed electric fields for better treatment of osteoarthritis.
Baohuoside I chemosensitises breast cancer to paclitaxel by suppressing extracellular vesicle/CXCL1 signal released from apoptotic cells.
Optimized AF4 combined with density cushion ultracentrifugation enables profiling of high-purity human blood extracellular vesicles.
Multiscale photocatalytic proximity labeling reveals cell surface neighbors on and between cells.
Regulated secretion of mutant p53 negatively affects T lymphocytes in the tumor microenvironment.
A novel lung cancer stem cell extracellular vesicles lncRNA ROLLCSC modulate non-stemness cancer cell plasticity through miR-5623-3p and miR-217-5p targeting lipid metabolism.
miRNA profiling of granulosa cell-derived exosomes reveals their role in promoting follicle development.
Injectable Multifunctional Composite Hydrogel as a Combination Therapy for Preventing Postsurgical Adhesion.
M2 microglia-derived exosome-loaded electroconductive hydrogel for enhancing neurological recovery after spinal cord injury.
Tumour-associated macrophage-derived DOCK7-enriched extracellular vesicles drive tumour metastasis in colorectal cancer via the RAC1/ABCA1 axis.
Palmitoylation of vacuole membrane protein 1 promotes small extracellular vesicle secretion via interaction with ALIX and influences intercellular communication.
Nutrient availability regulates the secretion and function of immune cell-derived extracellular vesicles through metabolic rewiring.
Herpes simplex virus type 1 modifies the protein composition of extracellular vesicles to promote neurite outgrowth and neuroinfection.
Exosomes From Human Umbilical Cord Stem Cells Suppress Macrophage-to-myofibroblast Transition, Alleviating Renal Fibrosis.
Novel injectable adhesive hydrogel loaded with exosomes for holistic repair of hemophilic articular cartilage defect.
The Microenvironment in an Experimental Model of Acute Pancreatitis Can Modify the Formation of the Protein Corona of sEVs, with Implications on Their Biological Function.
Fish Snx27 promotes viral products by modulating the innate immune response and exosomal machinery.
Ectopic endometrial stromal cell-derived extracellular vesicles encapsulating microRNA-25-3p induce endometrial collagen I deposition impairing decidualization in endometriosis.
Crucial roles of exosomes secreted from ganglioside GD3/GD2-positive glioma cells in enhancement of the malignant phenotypes and signals of GD3/GD2-negative glioma cells.
Exosomes loaded a smart bilayer-hydrogel scaffold with ROS-scavenging and macrophage-reprogramming properties for repairing cartilage defect.
Extracellular vesicles miR-31-5p promotes pancreatic cancer chemoresistance via regulating LATS2-Hippo pathway and promoting SPARC secretion from pancreatic stellate cells.
3D-hUMSCs Exosomes Ameliorate Vitiligo by Simultaneously Potentiating Treg Cells-Mediated Immunosuppression and Suppressing Oxidative Stress-Induced Melanocyte Damage.
Nicotinamide metabolism face-off between macrophages and fibroblasts manipulates the microenvironment in gastric cancer.
Identification of energy metabolism anomalies and serum biomarkers in the progression of premature ovarian failure via extracellular vesicles' proteomic and metabolomic profiles.
Activated STING-containing R-EVs from iPSC-derived MSCs promote antitumor immunity.
BMSC-derived Exosomes Ameliorate Peritoneal Dialysis-associated Peritoneal Fibrosis via the Mir-27a-3p/TP53 Pathway.
Chemotherapy-elicited extracellular vesicle CXCL1 from dying cells promotes triple-negative breast cancer metastasis by activating TAM/PD-L1 signaling.
Human umbilical cord mesenchymal stem cell-derived exosomes ameliorate renal fibrosis in diabetic nephropathy by targeting Hedgehog/SMO signaling.
Insights into the function of ESCRT complex and LBPA in ASFV infection.
Ferroptosis-dependent breast cancer cell-derived exosomes inhibit migration and invasion of breast cancer cells by suppressing M2 macrophage polarization.
The iron chelator deferriferrichrysin induces paraptosis via extracellular signal-related kinase activation in cancer cells.
Pancreatic stellate cell-derived exosomal tRF-19-PNR8YPJZ promotes proliferation and mobility of pancreatic cancer through AXIN2.
Follicular fluid derived exosomal miR-4449 regulates cell proliferation and oxidative stress by targeting KEAP1 in human granulosa cell lines KGN and COV434.
Extracellular Vesicle MicroRNAs From Corneal Stromal Stem Cell Enhance Stemness of Limbal Epithelial Stem Cells by Targeting the Notch Pathway.
TRIM16-mediated lysophagy suppresses high-glucose-accumulated neuronal Aβ.
TiO(2) nanoparticles promote tumor metastasis by eliciting pro-metastatic extracellular vesicles.
Nanotopographical Cues Tune the Therapeutic Potential of Extracellular Vesicles for the Treatment of Aged Skeletal Muscle Injuries.
Stress granules plug and stabilize damaged endolysosomal membranes.
GBP2 upregulated in LPS-stimulated macrophages-derived exosomes accelerates septic lung injury by activating epithelial cell NLRP3 signaling.
Autocrine role of senescent cardiac fibroblasts-derived extracellular vesicles.
SIRT2 regulates extracellular vesicle-mediated liver-bone communication.
M2 Macrophage-Derived sEV Regulate Pro-Inflammatory CCR2(+) Macrophage Subpopulations to Favor Post-AMI Cardiac Repair.
Epsin1-mediated exosomal sorting of Dll4 modulates the tubular-macrophage crosstalk in diabetic nephropathy.
ATG5 provides host protection acting as a switch in the atg8ylation cascade between autophagy and secretion.
Canocapavir Is a Novel Capsid Assembly Modulator Inducing a Conformational Change of the Linker Region of HBV Core Protein.
SERS spectroscopy with machine learning to analyze human plasma derived sEVs for coronary artery disease diagnosis and prognosis.
Extracellular vesicles from Zika virus-infected cells display viral E protein that binds ZIKV-neutralizing antibodies to prevent infection enhancement.
Dendritic cell-derived exosomal miR-3064-5p inhibits SIRT6/PCSK9 to protect the blood-brain barrier after subarachnoid hemorrhage.
Tanshinone IIA enhances the therapeutic efficacy of mesenchymal stem cells derived exosomes in myocardial ischemia/reperfusion injury via up-regulating miR-223-5p.
Autophagy and exosomes coordinately mediate quercetin's protective effects on alcoholic liver disease.
EFFECT OF EXOSOMES DERIVED FROM BONE MARROW MESENCHYMAL STEM CELLS ON PROGRAMMED CELL DEATH IN BLAST-INDUCED LUNG INJURY IN RATS.
BMSC-derived extracellular vesicles promoted osteogenesis via Axin2 inhibition by delivering MiR-16-5p.
Phospho-RNA-Seq Highlights Specific Small RNA Profiles in Plasma Extracellular Vesicles.
Single-cell transcriptome sequencing-based analysis: probing the mechanisms of glycoprotein NMB regulation of epithelial cells involved in silicosis.
Extracellular vesicle-associated tyrosine kinase-like orphan receptors ROR1 and ROR2 promote breast cancer progression.
Changes in urinary exosomal protein CALM1 may serve as an early noninvasive biomarker for diagnosing diabetic kidney disease.
Macrophage-derived exosomal miR-195a-5p impairs tubular epithelial cells mitochondria in acute kidney injury mice.
Exosomal microRNA-4535 of Melanoma Stem Cells Promotes Metastasis by Inhibiting Autophagy Pathway.
NAMPT encapsulated by extracellular vesicles from young adipose-derived mesenchymal stem cells treated tendinopathy in a "One-Stone-Two-Birds" manner.
Extracellular vesicles from mesenchymal stem cells reduce neuroinflammation in hippocampus and restore cognitive function in hyperammonemic rats.
Manipulation of PD-L1 Endosomal Trafficking Promotes Anticancer Immunity.
CLIC and membrane wound repair pathways enable pandemic norovirus entry and infection.
Extracellular vesicles released from macrophages modulates interleukin-1β in astrocytic and neuronal cells.
Human umbilical cord mesenchymal stem cell exosomes alleviate acute kidney injury by inhibiting pyroptosis in rats and NRK-52E cells.
Dual-engineered cartilage-targeting extracellular vesicles derived from mesenchymal stem cells enhance osteoarthritis treatment via miR-223/NLRP3/pyroptosis axis: Toward a precision therapy.
Ferritinophagy-mediated apoptosis and paraptosis induction involved MAPK and PI3K/AKT pathway in mechanism of an iron chelator.
MiR-1246b, a novel miRNA molecule of extracellular vesicles in bronchoalveolar lavage fluid, promotes nodule growth through FGF14 in patients with lung cancer.
Glutamine metabolic microenvironment drives M2 macrophage polarization to mediate trastuzumab resistance in HER2-positive gastric cancer.
Exosomes-loaded electroconductive nerve dressing for nerve regeneration and pain relief against diabetic peripheral nerve injury.
Prostate cancer cells synergistically defend against CD8(+) T cells by secreting exosomal PD-L1.
Exosomes Derived from Hypoxia-Cultured Human Adipose Stem Cells Alleviate Articular Chondrocyte Inflammaging and Post-Traumatic Osteoarthritis Progression.
Tumor-derived exosomes orchestrate the microRNA-128-3p/ELF4/CDX2 axis to facilitate the growth and metastasis of gastric cancer via delivery of LINC01091.
Chitosan Nerve Grafts Incorporated with SKP-SC-EVs Induce Peripheral Nerve Regeneration.
Exosomal lipid PI4P regulates small extracellular vesicle secretion by modulating intraluminal vesicle formation.
Characterizing the differential distribution and targets of Sumo1 and Sumo2 in the mouse brain.
Rejuvenation of tendon stem/progenitor cells for functional tendon regeneration through platelet-derived exosomes loaded with recombinant Yap1.
LncRNA H19-rich extracellular vesicles derived from gastric cancer stem cells facilitate tumorigenicity and metastasis via mediating intratumor communication network.
Exosomes Derived from Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation through the Wnt3a/β-Catenin Signaling Pathway.
Proteomic Profiling and Functional Analysis of B Cell-Derived Exosomes upon Pneumocystis Infection.
Macrophages with Different Polarization Phenotypes Influence Cementoblast Mineralization through Exosomes.
Hypoxic pancreatic cancer derived exosomal miR-30b-5p promotes tumor angiogenesis by inhibiting GJA1 expression.
Extracellular vesicle-associated microRNA-30b-5p activates macrophages through the SIRT1/ NF-κB pathway in cell senescence.
Extracellular Vesicle-Mediated Delivery of Ultrasmall Superparamagnetic Iron Oxide Nanoparticles to Mice Brain.
Exosomal miR-7002-5p derived from highglucose-induced macrophages suppresses autophagy in tubular epithelial cells by targeting Atg9b.
Peritoneal M2 macrophage-derived extracellular vesicles as natural multitarget nanotherapeutics to attenuate cytokine storms after severe infections.
Injectable cartilage matrix hydrogel loaded with cartilage endplate stem cells engineered to release exosomes for non-invasive treatment of intervertebral disc degeneration.
Extracellular vesicle fusion visualized by cryo-electron microscopy.
Vasorin-containing small extracellular vesicles retard intervertebral disc degeneration utilizing an injectable thermoresponsive delivery system.
Elaiophylin triggers paraptosis and preferentially kills ovarian cancer drug-resistant cells by inducing MAPK hyperactivation.
Neural stem cell‑derived exosomes transfer miR‑124‑3p into cells to inhibit glioma growth by targeting FLOT2.
Exosomes Derived from Bone Marrow Mesenchymal Stem Cells Alleviate Ischemia-Reperfusion Injury and Promote Survival of Skin Flaps in Rats.
Extracellular vesicles microRNA-592 of melanoma stem cells promotes metastasis through activation of MAPK/ERK signaling pathway by targeting PTPN7 in non-stemness melanoma cells.
Melanoma stem cells promote metastasis via exosomal miR-1268a inactivation of autophagy.
Cancer-derived exosomal circ_0038138 enhances glycolysis, growth, and metastasis of gastric adenocarcinoma via the miR-198/EZH2 axis.
HBV induced the discharge of intrinsic antiviral miRNAs in HBV-replicating hepatocytes via extracellular vesicles to facilitate its replication.
Multiplexed mRNA analysis of brain-derived extracellular vesicles upon experimental stroke in mice reveals increased mRNA content with potential relevance to inflammation and recovery processes.
Exosomes-derived miR-125-5p from cartilage endplate stem cells regulates autophagy and ECM metabolism in nucleus pulposus by targeting SUV38H1.
In Vitro and In Vivo Analysis of Extracellular Vesicle-Mediated Metastasis Using a Bright, Red-Shifted Bioluminescent Reporter Protein.
Thioredoxin upregulation delays diabetes-induced photoreceptor cell degeneration via AMPK-mediated autophagy and exosome secretion.
Bladder Cancer Extracellular Vesicles Elicit a CD8 T Cell-Mediated Antitumor Immunity.
Serum exosomal proteomics analysis of lung adenocarcinoma to discover new tumor markers.
Recruitment of DNA to tumor-derived microvesicles.
Enhancement of Osteoblast Function through Extracellular Vesicles Derived from Adipose-Derived Stem Cells.
Extracellular vesicles derived from human umbilical cord mesenchymal stem cells alleviate osteoarthritis of the knee in mice model by interacting with METTL3 to reduce m6A of NLRP3 in macrophage.
Tsc2 mutation induces renal tubular cell nonautonomous disease.
Inflammatory capacity of exosomes released in the early stages of acute pancreatitis predicts the severity of the disease.
In Vivo Visualized Tracking of Tumor-Derived Extracellular Vesicles Using CRISPR-Cas9 System.
A Dual-Reporter Platform for Screening Tumor-Targeted Extracellular Vesicles.
Tumor-derived extracellular vesicles confer 5-fluorouracil resistance in esophageal cancer via long noncoding RNA AC116025.2 delivery.
Improving the circulation time and renal therapeutic potency of extracellular vesicles using an endogenous ligand binding strategy.
Intercellular transfer of activated STING triggered by RAB22A-mediated non-canonical autophagy promotes antitumor immunity.
Effect of plasma-derived extracellular vesicles on angiogenesis and the ensuing proliferative diabetic retinopathy through a miR-30b-dependent mechanism.
Jianpi Huayu decoction inhibits the epithelial-mesenchymal transition of hepatocellular carcinoma cells by suppressing exosomal miR-23a-3p/Smad signaling.
Discovery of a Nur77-mediated cytoplasmic vacuolation and paraptosis inducer (4-PQBH) for the treatment of hepatocellular carcinoma.
Low-metastatic melanoma cells acquire enhanced metastatic capability via exosomal transfer of miR-199a-1-5p from highly metastatic melanoma cells.
Tsc Gene Locus Disruption and Differences in Renal Epithelial Extracellular Vesicles.
LncRNA FOXP4-AS1 Promotes Progression of Ewing Sarcoma and Is Associated With Immune Infiltrates.
Development of a novel RNAi therapy: Engineered miR-31 exosomes promoted the healing of diabetic wounds.
Tumor Necrosis Factor-stimulated Gene-6 (TSG-6) Secreted by BMSCs Regulates Activated Astrocytes by Inhibiting NF-κB Signaling Pathway to Ameliorate Blood Brain Barrier Damage After Intracerebral Hemorrhage.
Human Adipose Mesenchymal Stem Cell-derived Exosomes Protect Mice from DSS-Induced Inflammatory Bowel Disease by Promoting Intestinal-stem-cell and Epithelial Regeneration.
A novel delivery nanobiotechnology: engineered miR-181b exosomes improved osteointegration by regulating macrophage polarization.
Engineering Extracellular Vesicles Restore the Impaired Cellular Uptake and Attenuate Intervertebral Disc Degeneration.
Macrophage exosomes transfer angiotensin II type 1 receptor to lung fibroblasts mediating bleomycin-induced pulmonary fibrosis.
Neddylation of Coro1a determines the fate of multivesicular bodies and biogenesis of extracellular vesicles.
Tenascin-C expression in the lymph node pre-metastatic niche in muscle-invasive bladder cancer.
Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway.
Osteosarcoma-derived exosomal miR-501-3p promotes osteoclastogenesis and aggravates bone loss.
Extracellular vesicles derived from LPS-preconditioned human synovial mesenchymal stem cells inhibit extracellular matrix degradation and prevent osteoarthritis of the knee in a mouse model.
TGF-β1-mediated exosomal lnc-MMP2-2 increases blood-brain barrier permeability via the miRNA-1207-5p/EPB41L5 axis to promote non-small cell lung cancer brain metastasis.
SPP1 derived from silica-exposed macrophage exosomes triggers fibroblast transdifferentiation.
EVs Containing Host Restriction Factor IFITM3 Inhibited ZIKV Infection of Fetuses in Pregnant Mice through Trans-placenta Delivery.
Neuronal extracellular vesicle derived miR-98 prevents salvageable neurons from microglial phagocytosis in acute ischemic stroke.
Mesenchymal Stem Cell-Derived Extracellular Vesicles Attenuate Mitochondrial Damage and Inflammation by Stabilizing Mitochondrial DNA.
RAB31 marks and controls an ESCRT-independent exosome pathway.
Hypoxic pancreatic stellate cell-derived exosomal mirnas promote proliferation and invasion of pancreatic cancer through the PTEN/AKT pathway.
Characterization of pendrin in urinary extracellular vesicles in a rat model of aldosterone excess and in human primary aldosteronism.
Human umbilical vein endothelial cells derived-exosomes promote osteosarcoma cell stemness by activating Notch signaling pathway.
Extracellular vesicles derived from lipoaspirate fluid promote fat graft survival.
Surface Nanosieving Polyether Sulfone Particles with Graphene Oxide Encapsulation for the Negative Isolation toward Extracellular Vesicles.
ALG2 regulates type I interferon responses by inhibiting STING trafficking.
Extracellular vesicles package dsDNA to aggravate Crohn's disease by activating the STING pathway.
Cartilage endplate stem cells inhibit intervertebral disc degeneration by releasing exosomes to nucleus pulposus cells to activate Akt/autophagy.
The tissue origin effect of extracellular vesicles on cartilage and bone regeneration.
Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles.
Similar Repair Effects of Human Placenta, Bone Marrow Mesenchymal Stem Cells, and Their Exosomes for Damaged SVOG Ovarian Granulosa Cells.
Extracellular vesicle-mediated delivery of miR-101 inhibits lung metastasis in osteosarcoma.
Plasma Exosomal miRNA Expression Profile as Oxaliplatin-Based Chemoresistant Biomarkers in Colorectal Adenocarcinoma.
Bovine Milk Exosomes Affect Proliferation and Protect Macrophages against Cisplatin-Induced Cytotoxicity.
Exosomes derived from TSG-6 modified mesenchymal stromal cells attenuate scar formation during wound healing.
Profilin 2 promotes growth, metastasis, and angiogenesis of small cell lung cancer through cancer-derived exosomes.
Isolation of extracellular vesicles from intestinal tissue in a mouse model of intestinal ischemia/reperfusion injury.
DNA Damage Regulates Senescence-Associated Extracellular Vesicle Release via the Ceramide Pathway to Prevent Excessive Inflammatory Responses.
Tuberous Sclerosis Complex Axis Controls Renal Extracellular Vesicle Production and Protein Content.
The Late Domain of Prototype Foamy Virus Gag Facilitates Autophagic Clearance of Stress Granules by Promoting Amphisome Formation.
Extracellular vesicles transmitted miR-31-5p promotes sorafenib resistance by targeting MLH1 in renal cell carcinoma.
Circulating exosomal small RNAs are promising non-invasive diagnostic biomarkers for gastric cancer.
Exosome-mediated Hic-5 regulates proliferation and apoptosis of osteosarcoma via Wnt/β-catenin signal pathway.
Endosomal membrane tension regulates ESCRT-III-dependent intra-lumenal vesicle formation.
Human umbilical cord-derived mesenchymal stem cells prevent the progression of early diabetic nephropathy through inhibiting inflammation and fibrosis.
Exosomes derived from atorvastatin-pretreated MSC accelerate diabetic wound repair by enhancing angiogenesis via AKT/eNOS pathway.
KLF4-mediated upregulation of CD9 and CD81 suppresses hepatocellular carcinoma development via JNK signaling.
Exosomal miR-125a-5p derived from silica-exposed macrophages induces fibroblast transdifferentiation.
Extracellular vesicles expressing a single-chain variable fragment of an HIV-1 specific antibody selectively target Env(+) tissues.
Exosomes from mesenchymal stem cells modulate endoplasmic reticulum stress to protect against nucleus pulposus cell death and ameliorate intervertebral disc degeneration in vivo.
Cocktail Strategy Based on NK Cell-Derived Exosomes and Their Biomimetic Nanoparticles for Dual Tumor Therapy.
O-GlcNAcylation of Thr(12)/Ser(56) in short-form O-GlcNAc transferase (sOGT) regulates its substrate selectivity.
Exosomes derived from human CD34(+) stem cells transfected with miR-26a prevent glucocorticoid-induced osteonecrosis of the femoral head by promoting angiogenesis and osteogenesis.
Ovarian cancer circulating extracelluar vesicles promote coagulation and have a potential in diagnosis: an iTRAQ based proteomic analysis.
Specific Decrease in B-Cell-Derived Extracellular Vesicles Enhances Post-Chemotherapeutic CD8(+) T Cell Responses.
The circRNA circPTPRA suppresses epithelial-mesenchymal transitioning and metastasis of NSCLC cells by sponging miR-96-5p.
Cluster of Differentiation 46 Is the Major Receptor in Human Blood-Brain Barrier Endothelial Cells for Uptake of Exosomes Derived from Brain-Metastatic Melanoma Cells (SK-Mel-28).
Microvesicle-Mediated Delivery of Minicircle DNA Results in Effective Gene-Directed Enzyme Prodrug Cancer Therapy.
Detection of exosomal tyrosine receptor kinase B as a potential biomarker in ovarian cancer.
Modulation of calreticulin expression reveals a novel exosome-mediated mechanism of Z variant α(1)-antitrypsin disposal.
Exosomes derived from breast cancer lung metastasis subpopulations promote tumor self-seeding.
TGF-β-mediated exosomal lnc-MMP2-2 regulates migration and invasion of lung cancer cells to the vasculature by promoting MMP2 expression.
Mycobacterium tuberculosis Type VII Secretion System Effectors Differentially Impact the ESCRT Endomembrane Damage Response.
CD8α(+)CD11c(+) Extracellular Vesicles in the Lungs Control Immune Homeostasis of the Respiratory Tract via TGF-β1 and IL-10.
Exosomes Induce Fibroblast Differentiation into Cancer-Associated Fibroblasts through TGFβ Signaling.
Exosomes Exploit the Virus Entry Machinery and Pathway To Transmit Alpha Interferon-Induced Antiviral Activity.
Circulating Exosomal miR-17-5p and miR-92a-3p Predict Pathologic Stage and Grade of Colorectal Cancer.
Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer.
Monocyte-derived exosomes upon exposure to cigarette smoke condensate alter their characteristics and show protective effect against cytotoxicity and HIV-1 replication.
Exosomes maintain cellular homeostasis by excreting harmful DNA from cells.
REG3β modifies cell tumor function by impairing extracellular vesicle uptake.
Small extracellular vesicles secreted from senescent cells promote cancer cell proliferation through EphA2.
Motile hepatocellular carcinoma cells preferentially secret sugar metabolism regulatory proteins via exosomes.
Involvement of exosomes in lung inflammation associated with experimental acute pancreatitis.
EpCAM-dependent extracellular vesicles from intestinal epithelial cells maintain intestinal tract immune balance.
Characterization of exosomes derived from ovarian cancer cells and normal ovarian epithelial cells by nanoparticle tracking analysis.
Regulation of exosomes released from normal ovarian epithelial cells and ovarian cancer cells.
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Exosomes mediate the cell-to-cell transmission of IFN-α-induced antiviral activity.
Functional polycystin-1 dosage governs autosomal dominant polycystic kidney disease severity.
Song J, Su G, Chen W, Xie X, Zhang Z
Frontiers in neurology 2026;17:1733679
Frontiers in neurology 2026;17:1733679
Hypoxia‑induced exosomal CAMTA1 promotes radio‑resistance in MDA‑MB‑231 cells by regulating NRG1 to mediate M2 macrophage polarization.
Li Q, Jiang M, Zhu B, Wei W, Xia L, Huang J, Gao H, Du M
International journal of oncology 2026 May;68(5)
International journal of oncology 2026 May;68(5)
Exosomes derived from Bcl-2-engineered iPSC-cardiomyocytes mitigate aortic valve calcification and inhibit cardiomyocyte apoptosis.
Li N, Xiao R, Zhu L, Cai L, Zhang Z, Sun L, Shi H, Ye H, Shao G, Gao J
International journal of pharmaceutics 2026 May 20;697:126877
International journal of pharmaceutics 2026 May 20;697:126877
Plasma tau-species positive neuron-derived extracellular vesicles in progressive supranuclear palsy.
Zheng Y, Cai H, Kou W, Liu G, Wang Y, Bai J, Piao Y, Liu X, Zhu X, Zhang J, Yu Z, Feng T
Brain : a journal of neurology 2026 Mar 6;
Brain : a journal of neurology 2026 Mar 6;
Spatiotemporal Sequential Delivery of Chidamide Regulates Macrophage Reprogramming in Lymphoma Microenvironment Through HDACs-STAT3 Pathway.
Dai B, Wang S, Peng X, Wu K, Wu M, Lu Z, Zhong H, Qian X, Tan S, Yang H, Sun T, Wang J, Zhang J, Jiang H, Tong Y, Chen T
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar 31;:e02791
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar 31;:e02791
Membrane-Confined CRISPR-Cas12a Activation via Split Activator for Wash-Free Detection of Tumor-Specific Extracellular Vesicles.
Ren Y, Wu R, Yang X, Yao B, Wang Y
ACS sensors 2026 Mar 27;11(3):2356-2365
ACS sensors 2026 Mar 27;11(3):2356-2365
Pyroptosis-Inducing Engineered Microparticles for Cancer Immunotherapy.
Hao T, Deng Z, Liu Y, Liu L, Deng D, Yang M, Geng Y, Sun Y, Yue B, Lovell JF, Liu Y, Lu L, Jin H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar 18;:e74886
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar 18;:e74886
Fibroblast-derived exosomes induce macrophage pyroptosis to mediate orthodontic bone remodeling through the mtDNA/NLRP3 axis.
Yu Q, Guo K, Yang Y, Liu H, Han Y, Yu X, Wang J, Zhao Y, Su X, Zhu K, Zheng S, Wang S, Li W, Huang Y
Journal of nanobiotechnology 2026 Mar 14;24(1)
Journal of nanobiotechnology 2026 Mar 14;24(1)
UBQLN1 Inhibition reduces MASH progression through downregulating SIKE/p38 MAPK pathway in hepatocyte.
Chen Y, Yang F, Zheng G, Wang Y, Liu L, Yan Y
Journal of nanobiotechnology 2026 Mar 11;24(1)
Journal of nanobiotechnology 2026 Mar 11;24(1)
Inhibition of ESCRT-III activates alternative pathways for protein degradation and secretion.
Fujiwara M, Sakai R, Takahashi M, Matsumoto G, Hashimoto T, Kabuta T
Neurochemistry international 2026 Jun;196:106153
Neurochemistry international 2026 Jun;196:106153
Titanium-guided neutrophil dynamics for inflammation resolution and tissue integration.
Wang F, Lin W, Liu L, Chen W, Wu L, Song W, He W, Yin Q, Xing M, Yuan Q
Biomaterials 2026 Jul;330:124048
Biomaterials 2026 Jul;330:124048
Selective peptide-guided transcytosis enhances extracellular vesicle-mediated siRNA delivery across the blood-brain barrier.
Fang J, Zhang L, Wang Y, Chen M, He Y, Zhang CY, Zhang Y, Jiang X, Li J
The Journal of biological chemistry 2026 Jan;302(1):110942
The Journal of biological chemistry 2026 Jan;302(1):110942
Tumor-Derived CDC37 Inhibits Antigen Cross-Presentation in Dendritic Cells and Impairs Anti-Tumor Immunity in Breast Cancer.
Wang R, Zhang Y, Meng X, Zhao J, Xing Y, Ouyang Q, Zhang N, Chen H, Miao N, Song E, Huang D
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(5):e06518
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(5):e06518
Investigating the Potential Role of Capsaicin in Facilitating the Spread of Coxsackievirus B3 via Extracellular Vesicles.
Chatterjee S, Kordbacheh R, Tilley H, Briordy D, Waldron RT, Cutts WD, Aleman J, Cook A, Dhanji R, Wong LR, Pandol SJ, Kim BJ, Fairweather D, Sin J
International journal of molecular sciences 2026 Jan 9;27(2)
International journal of molecular sciences 2026 Jan 9;27(2)
Proteomic analysis revealed the potential usefulness of faecal extracellular vesicles in colorectal cancer diagnosis.
Murakami Y, Sakamaki N, Ohiro Y
Scientific reports 2026 Jan 8;16(1):4863
Scientific reports 2026 Jan 8;16(1):4863
Peroxiredoxin 1 mediates bleomycin-induced acute lung injury in mice via macrophage NOD1/NF-κB axis.
Jiang G, Zhang Y, Long L, Zhang X, Yao T, Cheng X, Yu P, Zou L, He Y, Jiang M, Liu Q, Meng J
Respiratory research 2026 Jan 30;27(1)
Respiratory research 2026 Jan 30;27(1)
COPD airway epithelial cells-derived extracellular vesicles contribute to endothelial dysfunction and atherosclerosis via the miR-141-3p/PDCD4 axis.
Wang Z, Shi J, Liang Y, Li D, Luo Y, Zhang Y, Chen Y, Li N, Gai X, Sun Y
Journal of nanobiotechnology 2026 Feb 6;24(1)
Journal of nanobiotechnology 2026 Feb 6;24(1)
Enhanced release of ciliary extracellular vesicles suppresses cell migration and promotes cell aggregation.
Hara T, Nakazato R, Shirakawa K, Ijaz F, Uemura K, Takahashi S, Ikegami K
Cell structure and function 2026 Feb 20;51(1):67-79
Cell structure and function 2026 Feb 20;51(1):67-79
Targeted inhibition of PARP-1 in pulmonary epithelial cells and macrophages via SPA-functionalized microparticles attenuates sepsis-induced lung injury.
Xie X, Wu M, Geng Y, Bai J, Ma C, Yan Y, Liu Y, Lu L, Zhan L
Materials today. Bio 2026 Apr;37:102955
Materials today. Bio 2026 Apr;37:102955
Small extracellular vesicles derived from lipotoxic hepatocytes transport FASN to promote hepatic stellate cell activation.
Shi Y, Yi L, Chen Y, Yang F, Qian H, Abouelnazar FA, Yan Y, Wang Y
Hepatology international 2026 Apr;20(2):451-463
Hepatology international 2026 Apr;20(2):451-463
Spatiotemporally controlled pretargeted azide-functionalized M1 macrophage-derived exosome-based (68)Ga/(177)Lu theranostic system for PET imaging and targeted radiotherapy in breast cancer.
Zheng W, Wang Y, Wang X, Yan J, Wang L, Pan D, Xu Y, Chen C, Zhou X, Yang M
Biomaterials advances 2026 Apr;181:214623
Biomaterials advances 2026 Apr;181:214623
Ascites circRNA ASCOR Drives Platinum Resistance of High-Grade Serous Ovarian Cancer by Facilitating RPA1 Nuclear Translocation.
Liu H, Zhu C, Yao X, Liu Y, Zhu J, Li Y, Xu H, Peng C, Shan G, Chen L, Zhou Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(23):e18922
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(23):e18922
Extracellular vesicle-associated lncRNA LYPLAL1-DT mediates endothelial-cancer cell communication, promoting small cell lung cancer progression.
Zhang X, Hu C, Li Z, Lu J, Huo X, Cao L, Guo M, Li C, Liu X, Chen Z, Lv J, Du X
Extracellular vesicles and circulating nucleic acids 2025;6(4):1015-1033
Extracellular vesicles and circulating nucleic acids 2025;6(4):1015-1033
Proteomic Landscape of Small Extracellular Vesicles Derived From Gastric Juice and Identified TFF2 as a Specific Biomarker.
Fan R, Wu K, Yang J, Zhu B, Jiang T, Liu Y, Yuan B, Liu L, Sun Y, Sun X, Liu L, Luo W, Zhou C, Guo Y, Liu L
International journal of nanomedicine 2025;20:6929-6948
International journal of nanomedicine 2025;20:6929-6948
Hyperammonemia increases the release of pathological extracellular vesicles from monocytes by impairing lysosomal function and autophagy through the TNFα-cAMP-PKA-LC3 pathway.
Pedrosa MA, Izquierdo-Altarejos P, Llansola M, Felipo V
Frontiers in immunology 2025;16:1724800
Frontiers in immunology 2025;16:1724800
Silk fibroin-collagen hydrogel loaded with IGF1-CESCs attenuates intervertebral disk degeneration by accelerating annulus fibrosus healing in rats.
Tian Z, Shen Z, Chen H, Zhao P
Frontiers in pharmacology 2025;16:1552174
Frontiers in pharmacology 2025;16:1552174
Comprehensive exome profiling identifies ARHGEF12 mutation as a driver in gastric cancer with ovarian metastasis.
Zhang M, Chen G, Lin X, Zhang Y, Shi L, Li S, Li Y, Xiao X, Feng H
Theranostics 2025;15(16):8202-8221
Theranostics 2025;15(16):8202-8221
The Effects of M2 Macrophages-Derived Exosomes on Urethral Fibrosis and Stricture in Scar Formation.
Ren X, Wang Z, Wang J, Li X, Wei H, Liu C, Liu S, Zhu Y, Feng C, Yin Y, Tian Y, Wu M, Zeng X
ImmunoTargets and therapy 2025;14:151-173
ImmunoTargets and therapy 2025;14:151-173
Curcumin-primed milk-derived extracellular vesicles remodel hair follicle microenvironment for the treatment of androgenetic alopecia.
Hou C, Wang S, Li Z, Huang Q, Jiang Y, Zhou X, Ou R, Li D, Xu Y
Regenerative biomaterials 2025;12:rbaf051
Regenerative biomaterials 2025;12:rbaf051
Hypoxia-induced immunosuppression in uveal melanoma is mediated by CD63(+) exosomes delivering lactate to reprogram immune cells.
Dong L, Zheng S, Feng Y
Frontiers in molecular biosciences 2025;12:1743009
Frontiers in molecular biosciences 2025;12:1743009
Protecting and rejuvenating ageing skin by regulating endogenous hyaluronan metabolism using adipose-derived stem cell-secreted siRNAs.
Sun B, He Y, Zhang L, Liu S, Chen M, Pan J, Fang J, Wang Y, Jiang H, Liu X, Zhang CY, Li J
Frontiers in medicine 2025;12:1529936
Frontiers in medicine 2025;12:1529936
STING inhibits LINE-1 retrotransposition through sorting ORF1p to lysosomes for degradation.
Huang Y, Xu F, Wang L, Mei S, Zhao F, Wang L, Xie Y, Wei L, Hu Y, Gao Z, Xue T, Fang J, Guo F
EMBO reports 2025 Sep;26(18):4607-4630
EMBO reports 2025 Sep;26(18):4607-4630
Multidimensional Engineering of Extracellular Vesicles for Targeted Delivery and Microglial Reprograming in Spinal Cord Injury Repair.
Xiong W, Liu M, Wang J, Liu J, Zheng M, Chan P, Zhu Q, Li C, Kong G, Tang C, Fan J
ACS nano 2025 Sep 9;19(35):31551-31571
ACS nano 2025 Sep 9;19(35):31551-31571
Exosomes derived from human umbilical cord mesenchymal stem cells attenuate hepatic ischaemia-reperfusion injury via the let-7i-5p/Faslg axis.
Gao Y, He M, Bian CW, Yu R, Luo JJ, Xiang YM, Yang YX, Huang HF, Zeng Z
World journal of gastroenterology 2025 Sep 7;31(33):108653
World journal of gastroenterology 2025 Sep 7;31(33):108653
Polystyrene nanoplastics-induced methuosis in brain microvascular endothelial cells: Rescue via ESCRT membrane repair system.
Yin S, Kang Y, Du W, Tan X, Wang Z, Shao L, Liu J
Ecotoxicology and environmental safety 2025 Sep 15;303:118800
Ecotoxicology and environmental safety 2025 Sep 15;303:118800
Failure of efficient cardiac proteostatic adaptations to chronic cAMP-stress is associated with accelerated heart aging.
Perino MG, Calvo-Rubio Barrera M, Riordon DR, Agnetti G, Maltsev A, Parveen A, Morrell CH, Ahmet I, Chakir K, Tarasova YS, Qu JH, Tarasov KV, Lyashkov AE, Lukyanenko YO, Kadioglu H, Ranek M, De Cabo R, Lakatta EG
GeroScience 2025 Sep 1;
GeroScience 2025 Sep 1;
The exosomal miRNA-3184-3p derived from highly metastatic melanoma cells promotes metastatic competency via the positive feedback loop of NLK/Wnt/S100A11.
Chen Y, Zeng B, Xiang M, Han X, Zhang X, Chen H, Zhao Q, Liu D, Li X, Li J, Zhang Y, Shi L, Li B, Chen Y, Tang Y, Li J, Xing HR, Wang J
Biochemical pharmacology 2025 Oct;240:117086
Biochemical pharmacology 2025 Oct;240:117086
Aerobic Exercise Attenuates Autophagy-Lysosomal Flux Deficits via β2-AR-Mediated ESCRT-III Subunit CHMP4B in Mice With Human MAPT P301L.
Bi SG, Yu H, Gao TL, Wu JJ, Mao YM, Gong J, Wang FZ, Yang L, Chen J, Lan ZC, Shen MT, Nie YJ, Chai GS
Aging cell 2025 Oct;24(10):e70184
Aging cell 2025 Oct;24(10):e70184
Urinary extracellular vesicle RNAs as novel biomarkers for diagnosis and prognosis of lupus nephritis.
Zhang H, Zheng X, Huang S, Qian L, Wu J, Shi Z, Jia M, Bai Y, Jiang L, Jia S, Zen K, Yuan Y, Liang J, Liang H
Clinical kidney journal 2025 Oct;18(10):sfaf295
Clinical kidney journal 2025 Oct;18(10):sfaf295
Flemiphilippinin A induces paraptosis in lung cancer cells via c-Myc-driven endoplasmic reticulum stress and CHOP-mediated mitochondrial dysfunction.
Xu Z, Huang X, Su Q, Wang Q, Liu L, Shen Y, Liao L, Zou X, Yang S, Tang Y, Gao H, Yuan R
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Oct;146:157098
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Oct;146:157098
POSTN-Mediated Interplay of M1 Polarized Macrophage with Tendon-Derived Stem Cells to Drive Traumatic Heterotopic Ossification Formation through PTK7/ATK Signaling?
Liu H, Li X, Li M, Sun Z, Wang X, Li J, Xu B, Chen Q, Fan C, Ruan H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(40):e07951
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(40):e07951
Pak4-mediated crosstalk between necroptotic macrophages and tendon stem/progenitor cells contributes to traumatic heterotopic ossification formation.
Sun Z, Liu H, Xu Y, Chen Q, Luo G, Yuan Z, Chen Z, He K, Fan C, Li J, Ruan H
Bone research 2025 Oct 20;13(1):88
Bone research 2025 Oct 20;13(1):88
Generation of Cellular Biofactories for Scalable Production of Surface-Engineered Extracellular Vesicles via CRISPR Genome Editing.
Kawai-Harada Y, Scarborough T, Siraj N, Yedla J, Rennells T, Walton SP, Chan C, Harada M
bioRxiv : the preprint server for biology 2025 Oct 2;
bioRxiv : the preprint server for biology 2025 Oct 2;
Microneedles combining delivery of hUMSC-derived exosomes and EGCG mitigate UV-induced skin damage.
He C, Wang Z, Jiang Z, Zhou Y, Chen X, Zhang J, Wang B, Wang Q, Wu T, Li C, Jian Z
Journal of nanobiotechnology 2025 Oct 10;23(1):643
Journal of nanobiotechnology 2025 Oct 10;23(1):643
Efficient Scaling up EV-AAVs Production via Cellular Nanoporation for Familial Hypercholesterolaemia Therapy.
Yan Y, You Y, Ma S, Yi H, Chen G, Ni J, Chen C, Ke W, Li L, Bai R, Ran Y, Lu W, Zhu M, Zhang Y, Dai J, Qi M, Lan F, Lee AS, Zhang R, Liu X, Chen Z
Journal of extracellular vesicles 2025 Nov;14(11):e70186
Journal of extracellular vesicles 2025 Nov;14(11):e70186
VesicleVoyager: In Vivo Selection of Surface Displayed Proteins That Direct Extracellular Vesicles to Tissue-Specific Targets.
Kawai-Harada Y, Mardikoraem M, Makela AV, Lauro K, Lam J, Contag CH, Woldring D, Harada M
Journal of extracellular vesicles 2025 Nov;14(11):e70184
Journal of extracellular vesicles 2025 Nov;14(11):e70184
Gastric cancer-derived exosomal miR-196a-5p remodels the pre-metastatic niche for peritoneal dissemination.
Zhang Z, Wang M, Gao X, Tai G, Li F, Wang Z
Cellular signalling 2025 Nov;135:112039
Cellular signalling 2025 Nov;135:112039
Succinic Acid-Induced Macrophage Endocytosis Promotes Extracellular Vesicle-Based Integrin Beta1 Transfer Accelerating Fibroblast Activation and Sepsis-Associated Pulmonary Fibrosis.
Yang W, Tang R, Zhou Y, Zhang J, Mei S, Peng Y, Huang X, Xing S, Gao Y, Xu Q, He Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(43):e07411
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(43):e07411
ER stress induced extracellular vesicles secretion from macrophages promotes calcium oxalate crystals formation in kidney.
Yuan Y, Ma Y, Dai L, Jin X, Qi S, Yin Z
Molecular biomedicine 2025 Nov 17;6(1):110
Molecular biomedicine 2025 Nov 17;6(1):110
Umbilical Cord Mesenchymal Stromal Cell-Derived Extracellular Vesicles Transfer CD59 to Astrocytes to Alleviate Complement-Dependent Cytotoxicity.
Shen Q, Wang X, Ou Q, Wang Q, Zhao Z, Chen Z, Zhu X, Li D, Jin C, Gao F, Wang J, Lu L, Bi Y, Wan W, Guan Y, Xu GT, Xu JY, Tian H
Molecular neurobiology 2025 Nov 14;63(1):41
Molecular neurobiology 2025 Nov 14;63(1):41
Histone lactylation-induced GLI3 activation drives macrophage M1 polarization and exosomal SERPINE1 release in abdominal aortic aneurysm progression.
Yuan K, Liu J, Chen G, Wang P, Wei L
Cell death discovery 2025 Nov 10;11(1):523
Cell death discovery 2025 Nov 10;11(1):523
Exosomes enriched with miR-31-3p from keratinocytes under oxidative stress promote vitiligo progression by destructing melanocytes and activating CD8(+) T cells.
Ma J, Zhou Y, Chen J, Guo S, Zhang W, Yi X, Du P, Wang Y, Chen J, Li S, Gao T, Li C, Jian Z
International journal of biological macromolecules 2025 May;310(Pt 1):143070
International journal of biological macromolecules 2025 May;310(Pt 1):143070
Extracellular vesicles engineered to directly target encephalomyocarditis virus ameliorates multi-organ viremia in a lethal infection model.
Yue J, Yang Y, Idris A, Jin W, Zhang Y, Chen Y, Li X, Li H, Li S, Wen Y, Feng R, Xie J
Veterinary microbiology 2025 May;304:110448
Veterinary microbiology 2025 May;304:110448
Unusual chaetoglobosins and a new type of ferroptosis inducer from an endophytic fungus Chaetomium sp. UJN-EF006.
Wang YY, Wang YS, Li JJ, Wan ZY, Zhang H
Bioorganic chemistry 2025 May;158:108342
Bioorganic chemistry 2025 May;158:108342
Tumor-derived exosomal CCT6A serves as a matchmaker introducing chemokines to tumor-associated macrophages in pancreatic ductal adenocarcinoma.
Ma T, Guo WW, Zhang M, He W, Dongzhi C, Gongye X, Xia P, Chai Y, Chen Z, Zhu Y, Qu C, Liu J, Yang Z, Ma W, Tian M, Yuan Y
Cell death & disease 2025 May 15;16(1):382
Cell death & disease 2025 May 15;16(1):382
Breast cancer stem cell-derived exosomal lnc-PDGFD induces fibroblast-niche formation and promotes lung metastasis.
Tang T, Yang T, Xue H, Liu X, Yu J, Liang C, Li D, Xiang C, Zheng J, Wei L, Ma B
Oncogene 2025 Mar;44(9):601-617
Oncogene 2025 Mar;44(9):601-617
Decorin-mediated dermal papilla cell-derived exosomes regulate hair follicle growth and development through miR-129-2-3p/SMAD3/TGF-β axis.
Li J, Zhao B, Yu Y, Bao Z, Zheng F, Cai J, Chen Y, Wu X
International journal of biological macromolecules 2025 Mar;295:139292
International journal of biological macromolecules 2025 Mar;295:139292
Extracellular vesicle-packaged PKM2 from endometriotic stromal cells promotes endometrial collagen I deposition by inhibiting autophagy in endometriosis.
Zhu Y, Gao L, Zhang J, Li M, Zhou J, Zhou J
Cellular signalling 2025 Mar;127:111523
Cellular signalling 2025 Mar;127:111523
Bone marrow mesenchymal stem cell exosomes improve fracture union via remodeling metabolism in nonunion rat model.
Li C, Chen M, Guo L, Yu D, Xu Z, Chen B, Xiao Z
Journal of orthopaedic surgery and research 2025 Mar 25;20(1):308
Journal of orthopaedic surgery and research 2025 Mar 25;20(1):308
Radiotherapy-derived engineered stem cell exosomes improve anti-glioma immunotherapy by promoting the formation of tertiary lymphoid structure and improve the release of type I interferon.
Li M, Lu L, Bao Q, Zhou M, Nie B, Liu Y, Shu K, Lei T, Zhu M
Journal of nanobiotechnology 2025 Mar 22;23(1):239
Journal of nanobiotechnology 2025 Mar 22;23(1):239
Platelet Membrane and miR-181a-5p Doubly Optimized Nanovesicles Enhance Cardiac Repair Post-Myocardial Infarction through Macrophage Polarization.
Liu D, Wang X, Liu Z, Ding L, Liu M, Li T, Zeng S, Zheng M, Wang L, Zhang J, Zhang F, Li M, Liu G, Tang Y
ACS applied materials & interfaces 2025 Mar 19;17(11):16520-16532
ACS applied materials & interfaces 2025 Mar 19;17(11):16520-16532
Endocrine-exocrine miR-503-322 drives aging-associated pancreatitis via targeting MKNK1 in acinar cells.
Liu K, Lv T, He L, Tang W, Zhang Y, Xiao X, Li Y, Chang X, Wang S, Pandol SJ, Li L, Han X, Zhu Y
Nature communications 2025 Mar 17;16(1):2613
Nature communications 2025 Mar 17;16(1):2613
Psychological stress-induced ALKBH5 deficiency promotes tumour innervation and pancreatic cancer via extracellular vesicle transfer of RNA.
Chen Z, Zhou Y, Xue C, Zeng L, Deng S, Xu Z, Li M, Zhao H, He X, Liu S, Liu J, Liu S, Zhao S, Zhang S, Peng X, Wu X, Bai R, Zhuang L, Wu S, Zhang J, Lin D, Huang X, Zheng J
Nature cell biology 2025 Jun;27(6):1035-1047
Nature cell biology 2025 Jun;27(6):1035-1047
Mechanism of Tau protein incorporation into exosomes via cooperative recognition of KFERQ-like motifs by LAMP2A and HSP70.
Xu S, Liu K, Qian S, Wu J, Hu J, Zhou D, Zheng T
Neurochemistry international 2025 Jun;186:105976
Neurochemistry international 2025 Jun;186:105976
In Vivo Reprogramming of Tissue-Derived Extracellular Vesicles for Treating Chronic Tissue Injury Through Metabolic Engineering.
Zhao M, Liu S, Wang Y, Lou P, Lv K, Wu T, Li L, Wu Q, Zhu J, Lu Y, Wan M, Liu J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(21):e2415556
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(21):e2415556
Extracellular Vesicles from Peripheral Blood Mononuclear Cells of Hyperammonemic Rats Induce Neuroinflammation in Hippocampus, Impairing Memory and Learning in Normal Rats.
Izquierdo-Altarejos P, López-Gramaje A, Pedrosa MA, Sebestyén VE, Vazquez L, Martinez-Garcia M, Llansola M, Felipo V
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2025 Jun 7;20(1):65
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2025 Jun 7;20(1):65
VesicleVoyager: In vivo selection of surface displayed proteins that direct extracellular vesicles to tissue-specific targets.
Kawai-Harada Y, Mardikoraem M, Makela AV, Lauro K, Lam J, Contag CH, Woldring D, Harada M
bioRxiv : the preprint server for biology 2025 Jun 7;
bioRxiv : the preprint server for biology 2025 Jun 7;
A Novel Modulator of Resistance for Oxaliplatin-Based Therapy for Colorectal Cancer: The ESCRT Family Member VPS4A.
Abdelrazik NM, Patel A, Conn A, Sutton CW, Kantamneni S, Shnyder SD
Cells 2025 Jun 19;14(12)
Cells 2025 Jun 19;14(12)
DDX5 super-enhancer promotes vasculogenic mimicry formation and metastasis in nasopharyngeal carcinoma by enhancing ADAM10 transcription.
Xia T, Yin H, Zhu Q, Zhang K, Xie H, Shan Y, Zhang S, Zhu R, Li K, Miao M, Lu Y, Wang Z, Zhao J, You Y, You B
Cell reports. Medicine 2025 Jun 17;6(6):102146
Cell reports. Medicine 2025 Jun 17;6(6):102146
Tβ4-Engineered ADSC Extracellular Vesicles Rescue Cell Senescence Through Separable Microneedle Patches for Diabetic Wound Healing.
Ding Y, Wang J, Li J, Cheng Y, Zhou S, Zhang Y, Zhao Y, Zhou M
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jul;12(26):e2505009
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jul;12(26):e2505009
Glucocorticoid-Induced Muscle Satellite Cell-Derived Extracellular Vesicles Mediate Skeletal Muscle Atrophy via the miR-335-5p/MAPK11/iNOS Pathway.
Ma P, Wu J, Zhou R, Xue L, Luo X, Yan Y, Lu J, Dong Y, Geng J, Wang H
Biomolecules 2025 Jul 24;15(8)
Biomolecules 2025 Jul 24;15(8)
Extracellular vesicle-enriched secretome of adipose-derived stem cells upregulates clusterin to alleviate doxorubicin-induced apoptosis in cardiomyocytes.
Hsu WT, Kobuchi S, Chien TR, Chen IC, Hamada S, Tsujimoto M, Tsai IL, Wong YS, Tung KH, He YZ
Biology direct 2025 Jul 16;20(1):84
Biology direct 2025 Jul 16;20(1):84
Chronic sleep deprivation induces plasma exosome-derived miR-150-5p downregulation as a novel mechanism involved in Parkinson's disease progression by targeting DCLK1.
Liu L, Liu X, Zhang R, Sun X, Zhang K, Zheng B, Yang R, Yang K, Song G, Zhang Z
Journal of translational medicine 2025 Jul 11;23(1):781
Journal of translational medicine 2025 Jul 11;23(1):781
USP5 inhibition via bone marrow-targeted engineered exosomes for myeloproliferative neoplasms therapy.
Wang W, Jiang Y, Zhang D, Zhang X, Liang Q, Shi J, Zhou Y, Zhou F
Journal of nanobiotechnology 2025 Jul 11;23(1):501
Journal of nanobiotechnology 2025 Jul 11;23(1):501
Serum small extracellular vesicles-derived BST2 as a biomarker for papillary thyroid microcarcinoma promotes lymph node metastasis.
Cao Z, Wang Y, Wu J, Tang X, Qian Z, Zhang Z, Liu R, Liu P, Li Z, Xu X, Liu Z
Cancer gene therapy 2025 Jan;32(1):38-50
Cancer gene therapy 2025 Jan;32(1):38-50
Harnessing Tumor Cell-Derived Exosomes for Immune Rejection Management in Corneal Transplantation.
Yang J, Kang H, Liu Y, Lu S, Wu H, Zhang B, He Y, Zhou W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jan;12(2):e2409207
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jan;12(2):e2409207
Diagnostic role of circulating long non-coding RNA LINC00312 in patients with non-small cell lung cancer: a retrospective study.
Zhang R, Jiang Y, Gu J, Zhang X, Xie Y
BMC cancer 2025 Jan 9;25(1):47
BMC cancer 2025 Jan 9;25(1):47
Concurrent Detection of Protein and miRNA at the Single Extracellular Vesicle Level Using a Digital Dual CRISPR-Cas Assay.
Xu X, Zhang Y, Liu J, Wei S, Li N, Yao X, Wang M, Su X, Jing G, Xu J, Liu Y, Lu Y, Cheng J, Xu Y
ACS nano 2025 Jan 14;19(1):1271-1285
ACS nano 2025 Jan 14;19(1):1271-1285
In vivo evidence of increased vascular endothelial growth factor in patients with major depressive disorder.
Li K, Wang K, Xu SX, Xie XH, Tang Y, Zhang L, Liu Z
Journal of affective disorders 2025 Jan 1;368:151-159
Journal of affective disorders 2025 Jan 1;368:151-159
MFGE8 induces anti-PD-1 therapy resistance by promoting extracellular vesicle sorting of PD-L1.
Wang W, Chen J, Wang S, Sun X, Yang J, Yu P, Hu G, Wang J, Zhang J, Qiao S, Wang J, Zhang G, He Y, Feng H, Cai Z
Cell reports. Medicine 2025 Feb 18;6(2):101922
Cell reports. Medicine 2025 Feb 18;6(2):101922
α-Synuclein Promotes the Expression and Release of Neurofilament Light Chain from Oligodendrocytes in a Murine Model: Implication for Multiple System Atrophy?
Zheng Y, Kou W, Yang G, Cai H, Yang C, Li S, Zhu B, Wu J, Huang Y, Yu Z, Feng T
Annals of neurology 2025 Dec;98(6):1364-1379
Annals of neurology 2025 Dec;98(6):1364-1379
3D-cultured DFAT spheroid-derived exosomes promote aged wound healing via modulation of the NF-κB/Serpine1 pathway.
Ma X, Wei W, Zeng H, Dong M
Tissue & cell 2025 Dec;97:103049
Tissue & cell 2025 Dec;97:103049
A panel of miRNAs in serum extracellular vesicles serves as novel diagnostic biomarkers for MASLD.
Hu M, Huang H, Jia M, Xu M, Chen M, Wu J, Gu S, Liang H, Zhou H, Gong Y
Biomedical journal 2025 Dec;48(6):100838
Biomedical journal 2025 Dec;48(6):100838
The brown fat-enriched exosomal miR-206-3p attenuates hepatic lipogenesis by decreasing pentose phosphate pathway.
Yang LJ, Tang QK, Wang L, Song YJ, Xu ZY, Ma XN, Liu Y, Qian SW, Tang QQ, Tang Y
Life metabolism 2025 Dec;4(6):loaf028
Life metabolism 2025 Dec;4(6):loaf028
Mesenchymal stem cell-derived small extracellular vesicles-loaded GelMA microspheres enhance diabetic wound healing by promoting M2 macrophage polarization through p38 MAPK inhibition.
Li W, Chen J, Yu L, Ding L, Zhang X, Yan L, Shi M
Materials today. Bio 2025 Dec;35:102423
Materials today. Bio 2025 Dec;35:102423
Recruiting T-cells toward the brain for enhanced glioblastoma chemo-immunotherapy efficacy by co-delivery of cytokines and temozolomide via ultrasound-gated redox-responsive extracellular vesicles.
Dong L, Xu Q, Liu H, Li R, Yun Z, Yang H, Gu Z, Wei J, Guo H, Wei Z, Zhang H
Journal of nanobiotechnology 2025 Dec 7;23(1):766
Journal of nanobiotechnology 2025 Dec 7;23(1):766
Macrophage-derived exosomal miR-466i-5p and miR-365-2-5p stimulated by BMP-2 promote osteogenesis.
Lu R, Dong H, Li W, Wang N, Yao Y, Chen S
Journal of orthopaedic surgery and research 2025 Dec 31;21(1):70
Journal of orthopaedic surgery and research 2025 Dec 31;21(1):70
Tumor-secreted factors induce aberrant accumulation of vitamin A-enriched lipid droplets in the liver.
Huang X, Zhou W, Hou W, Zhou Y, Li M, Zhang Y, Zhang Q, Yan W, Zhang D, Lee HJ
Communications biology 2025 Dec 27;9(1):125
Communications biology 2025 Dec 27;9(1):125
Rab27a-mediated exosome secretion facilitates classical swine fever virus release and immune evasion.
Li N, Quan Y, Luo B, Chen X, Wang T, Gong Z, Zhang L, Guo K
Journal of virology 2025 Dec 23;99(12):e0148825
Journal of virology 2025 Dec 23;99(12):e0148825
Atosiban-conjugated 3WJ-pRNA nanoparticles delivering GAS1-enhanced extracellular vesicles: targeting the decidua to combat recurrent miscarriage.
Li YX, Wei SQ, Zheng PS
Journal of nanobiotechnology 2025 Dec 20;23(1):780
Journal of nanobiotechnology 2025 Dec 20;23(1):780
Liver-breast communication of adipocyte-oriented exosomes drives primary mammary cancer progression.
Li C, Lu Y, Li Y, Liu T, Deng H, Gao M, Zhou B, Liu J, Cai J, Huang D, Yang L, Jin J, Kuang D, Su S
Cell metabolism 2025 Dec 2;37(12):2402-2422.e18
Cell metabolism 2025 Dec 2;37(12):2402-2422.e18
Extracellular vesicles from obese visceral adipose promote pancreatic cancer development and resistance to immune checkpoint blockade therapy.
Xue C, Zhao S, Zhou Y, Chen Z, Liu J, Deng S, Zeng L, Zhao H, Xu Z, Li M, He X, Liu S, Liu S, Zhang S, Peng X, Wu X, Bai R, Zhuang L, Wu S, Zhang J, Lin D, Huang X, Zheng J
Cell metabolism 2025 Dec 2;37(12):2381-2401.e9
Cell metabolism 2025 Dec 2;37(12):2381-2401.e9
tsRNA-10105-enriched migrasomes mediate hepatocellular carcinoma immunosuppressive microenvironment by inducing M2 Macrophage polarization.
Pan L, Zhou R, Wen Z, Lin Y, Cai H, Lin C, Xu X, Ruan L, Zeng Y, Zhang H, Zhou Y, Hu X
Experimental cell research 2025 Dec 1;453(2):114729
Experimental cell research 2025 Dec 1;453(2):114729
Synergistic chemoimmunotherapy using pirarubicin-loaded tumor-derived extracellular vesicles for triple-negative breast cancer (TNBC).
Sun Q, Yu S, Shi R, Xu M, Ma P, Lv FY
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2025 Dec 1;215:107331
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2025 Dec 1;215:107331
An engineered M2 macrophage-derived exosomes-loaded electrospun biomimetic periosteum promotes cell recruitment, immunoregulation, and angiogenesis in bone regeneration.
Wen Z, Li S, Liu Y, Liu X, Qiu H, Che Y, Bian L, Zhou M
Bioactive materials 2025 Aug;50:95-115
Bioactive materials 2025 Aug;50:95-115
Anti-Her2 CAR-NK92 Cells and Their Exosomes: Generation, Characterization, and Selective Cytotoxicity Against Her2-Positive Tumor Cells.
Tîrziu A, Bojin FM, Gavriliuc OI, Buzan RM, Zbîrcea LE, Grijincu M, Păunescu V
International journal of molecular sciences 2025 Aug 7;26(15)
International journal of molecular sciences 2025 Aug 7;26(15)
Arachidonic acid triggers spermidine synthase secretion from primary tumor to induce skeletal muscle weakness upon irradiation.
Zhang X, Nie Z, Wang S, Ma Y, Han D, Hu T, Liu L, Men L, Zhang T, Wu X, Li X, Hu S, Yuan M, Liu L, Wang C, Xu P, Xiang L, Liu J, Zhang Y, Zhu D, Lei H, Zhang L, Li X, Zhao Y, Yan W
Cell metabolism 2025 Aug 5;37(8):1766-1782.e12
Cell metabolism 2025 Aug 5;37(8):1766-1782.e12
The Redox Enzyme Thioredoxin Is Increased in Plasma Extracellular Vesicles From Endurance-Trained Females in Response to Acute Exercise.
Sagini K, Selvarajah M, Romero S, Bassols-Citores E, Martin-Gracia B, Ramirez-Garrastacho M, Rise F, Endzeliņš E, Sadovska L, Skorinkina D, Boguševiča M, Cešeiko R, Čampa M, Klavina A, Linē A, Llorente A
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Aug 31;39(16):e70927
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Aug 31;39(16):e70927
Hypoxia-induced exosomal circNRIP1 activates cancer-associated fibroblasts to promote esophageal squamous cell carcinoma migration and invasion.
Qiao G, Li C, Wang M, Zhang W, Shi J, Meng B, Zhang L, Zhang R, Qi H, Xin S
BMC gastroenterology 2025 Aug 20;25(1):605
BMC gastroenterology 2025 Aug 20;25(1):605
Comparisons of miRNA profiles of exosomes derived from human iPSCs, ADSCs, and BMSCs and effects on chondrocyte function.
Chang LH, Chuang SC, Wu SC, Fu YC, Chen JW, Wu CW, Lin YS, Liu CY, Chung YH, Chang JK, Chen CH, Ho ML
Bone & joint research 2025 Aug 18;14(8):696-712
Bone & joint research 2025 Aug 18;14(8):696-712
Development of an Effective Isolation Method for Plasma Extracellular Vesicles Excluding Lipoproteins by Precipitation With Polyethylene Glycol.
Otani K, Fujioka Y, Okada M, Yamawaki H
Journal of extracellular biology 2025 Apr;4(4):e70047
Journal of extracellular biology 2025 Apr;4(4):e70047
Physically engineered extracellular vesicles targeted delivering miR-21-5p to promote renoprotection after renal ischemia-reperfusion injury.
Wu D, Ma W, Wang L, Long C, Chen S, Liu J, Qian Y, Zhao J, Zhou C, Jia R
Materials today. Bio 2025 Apr;31:101528
Materials today. Bio 2025 Apr;31:101528
Exosome-loaded tannic acid-thioctic acid hydrogel enhances wound healing in coagulation disorders.
Tu Y, Zheng W, Ding Z, Xiang J, Yang Q, Liu Y, Cao J, Shen Y, Tang Z, Lin S, Fan L, Xu Y, Chen B
Materials today. Bio 2025 Apr;31:101496
Materials today. Bio 2025 Apr;31:101496
Proteomic Analysis of Human Follicular Fluid-Derived Exosomes Reveals That Insufficient Folliculogenesis in Aging Women is Associated With Infertility.
Liu Z, Zhou Q, Zan J, Tian J, Zhang Y, Wu F, Zhao H, Peng Q, Liu S, Chen Q, Liu E, Liao Z, Zou P, Mei L, Wang W, Dong S, Niu L, Wu S, He L, Zhou X, Jin Y, Li P, Yang S
Molecular & cellular proteomics : MCP 2025 Apr;24(4):100930
Molecular & cellular proteomics : MCP 2025 Apr;24(4):100930
tsRNA-12391-Modified Adipose Mesenchymal Stem Cell-Derived Exosomes Mitigate Cartilage Degeneration in Osteoarthritis by Enhancing Mitophagy.
Shi J, Zhao G, Wang S, Wei Y, Wu J, Huang G, Chen J, Xia J
Biotechnology journal 2025 Apr;20(4):e202400611
Biotechnology journal 2025 Apr;20(4):e202400611
Dendritic Cell Derived-Extracellular Vesicles Engineered to Express Interleukin-12 and Anti-CTLA-4 on Their Surface for Combinational Cancer Immunotherapy.
Chen J, Tan Q, Yang Z, Chen W, Zhou E, Li M, Deng J, Wu Y, Liu J, Xu J, Guo M, Jin Y
Journal of extracellular vesicles 2025 Apr;14(4):e70068
Journal of extracellular vesicles 2025 Apr;14(4):e70068
LIMA1 O-GlcNAcylation Promotes Hepatic Lipid Deposition through Inducing β-catenin-Regulated FASn Expression in Metabolic Dysfunction-Associated Steatotic Liver Disease.
Yang F, Chen Y, Zheng G, Gu K, Fan L, Li T, Zhu L, Yan Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(15):e2415941
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(15):e2415941
Classical swine fever virus recruits ALIX and ESCRT-III to facilitate viral budding.
Chen J, Yang H, Wan M, Cheng Y, Bai J, Li Y, Chen J, Zhao B, Gao F, Zhou B
mBio 2025 Apr 9;16(4):e0261824
mBio 2025 Apr 9;16(4):e0261824
YWHAE affects proliferation, migration and apoptosis of colorectal cancer by regulating extracellular vesicles secretion and Wnt/β-catenin signaling pathway.
Ye Y, Fang J, Wang Y, Xu B, Li Z, Chang L, Xue X, Li J
Translational cancer research 2025 Apr 30;14(4):2260-2273
Translational cancer research 2025 Apr 30;14(4):2260-2273
The assembly of RAB22A/TMEM33/RTN4 initiates a secretory ER-phagy pathway.
Zheng X, Fang D, Shan H, Xiao B, Wei D, Ouyang Y, Huo L, Zhang Z, Wu Y, Zhang R, Kang T, Gao Y
Cell discovery 2025 Apr 29;11(1):41
Cell discovery 2025 Apr 29;11(1):41
Microglia-targeting nanosystems that cooperatively deliver Chinese herbal ingredients alleviate behavioral and cognitive deficits in Alzheimer's disease model mice.
Zhou P, Chao Q, Li C, Wang N, Guo S, Wang P, Ge P, Li C, Guo R, Yang N, Lu Z, Tang Z, Zhang Q, Fu T, Xiao Q, Zhu H
Journal of nanobiotechnology 2025 Apr 24;23(1):313
Journal of nanobiotechnology 2025 Apr 24;23(1):313
In vitro study on the promotion of osteogenic differentiation by mitochondrial-derived vesicles through activation of inflammation and reprogramming of metabolic pathways.
Pan C, Cheng C, Zhong S, Li S, Tan W, Yao Y
Journal of orthopaedic surgery and research 2025 Apr 17;20(1):388
Journal of orthopaedic surgery and research 2025 Apr 17;20(1):388
Microvesicles carrying EV71 virions cross BBB through endocytic pathway to induce brain injury.
Tian X, Liu B, Li L, Yuan M, You Q, Zhang R, Chen D, Cheng M, Zheng N, He M, Wu Z
Cell communication and signaling : CCS 2025 Apr 14;23(1):183
Cell communication and signaling : CCS 2025 Apr 14;23(1):183
Injectable ECM-mimetic dynamic hydrogels abolish ferroptosis-induced post-discectomy herniation through delivering nucleus pulposus progenitor cell-derived exosomes.
Wang W, Cheng Z, Yu M, Liu K, Duan H, Zhang Y, Huang X, Li M, Li C, Hu Y, Luo Z, Liu M
Nature communications 2025 Apr 1;16(1):3131
Nature communications 2025 Apr 1;16(1):3131
A methodological primer of extracellular vesicles isolation and characterization via different techniques.
Aliakbari F, Stocek NB, Cole-André M, Gomes J, Fanchini G, Pasternak SH, Christiansen G, Morshedi D, Volkening K, Strong MJ
Biology methods & protocols 2024;9(1):bpae009
Biology methods & protocols 2024;9(1):bpae009
Inhibition of triple-negative breast cancer growth via delphinidin-mediated suppression of the JAK2/STAT3/PD-L1 pathway.
Yu X, Song X, Yan J, Xiong Z, Zheng L, Luo Y, Deng F, Zhu Y
Food & nutrition research 2024;68
Food & nutrition research 2024;68
Exosomal SLC16A1-AS1-induced M2 macrophages polarization facilitates hepatocellular carcinoma progression.
Hu Y, Li Y, Xiong H, Zhang Y, Wang F, Zhuo W, Zeng Z, Zhao Y, Wang H, Hu P, Han S, Huang Y, Lv G, Zhao G
International journal of biological sciences 2024;20(11):4341-4363
International journal of biological sciences 2024;20(11):4341-4363
Investigating Neuroplasticity Changes Reflected by BDNF Levels in Astrocyte-Derived Extracellular Vesicles in Patients with Depression.
Li K, Wang K, Xu SX, Xie XH, Tang Y, Zhang L, Liu Z
International journal of nanomedicine 2024;19:8971-8985
International journal of nanomedicine 2024;19:8971-8985
Human umbilical cord mesenchymal stem cells derived-exosomes alleviate LPS-induced cervical inflammation and epithelial-mesenchymal transition.
Yi C, Wang H, Din MAU, Xia Y, Akanyibah FA, Mao F
American journal of translational research 2024;16(11):6903-6913
American journal of translational research 2024;16(11):6903-6913
Glioblastoma-derived exosomes promote lipid accumulation and induce ferroptosis in dendritic cells via the NRF2/GPX4 pathway.
Yang J, Zhang M, Zhang X, Zhou Y, Ma T, Liang J, Zhang J
Frontiers in immunology 2024;15:1439191
Frontiers in immunology 2024;15:1439191
Bone marrow mesenchymal stem cell-derived exosomes improve cancer drug delivery in human cell lines and a mouse osteosarcoma model.
Cai W, He D
Frontiers in oncology 2024;14:1482087
Frontiers in oncology 2024;14:1482087
ECM1 and ANXA1 in urinary extracellular vesicles serve as biomarkers for breast cancer.
Huang H, Wan J, Ao X, Qu S, Jia M, Zhao K, Liang J, Zen K, Liang H
Frontiers in oncology 2024;14:1408492
Frontiers in oncology 2024;14:1408492
Engineered nanovesicles from activated neutrophils with enriched bactericidal proteins have molecular debridement ability and promote infectious wound healing.
Jin H, Wen X, Sun R, Yu Y, Guo Z, Yang Y, Li L, Sun B
Burns & trauma 2024;12:tkae018
Burns & trauma 2024;12:tkae018
Exosomes Derived from Meningitic Escherichia coli-Infected Brain Microvascular Endothelial Cells Facilitate Astrocyte Activation.
Yang R, Qu X, Zhi S, Wang J, Fu J, Tan C, Chen H, Wang X
Molecular neurobiology 2024 Sep;61(9):7195-7210
Molecular neurobiology 2024 Sep;61(9):7195-7210
Bone marrow stromal and anterior cruciate ligament remnant cell co-culture-derived extracellular vesicles promote cell activity in both cell types.
Lin SY, Wu SC, Liu ZM, Chou PP, Zhao C, Ho ML, Lu CC
Journal of cellular and molecular medicine 2024 Sep;28(17):e70049
Journal of cellular and molecular medicine 2024 Sep;28(17):e70049
Effect of lyophilized exosomes derived from umbilical cord stem cells on chronic anterior cruciate ligament cell injury.
Lo HL, Lin SY, Ho CJ, Ming-Kung Y, Lu CC
Journal of orthopaedic surgery and research 2024 Sep 9;19(1):554
Journal of orthopaedic surgery and research 2024 Sep 9;19(1):554
GRP75 triggers white adipose tissue browning to promote cancer-associated cachexia.
Chen X, Wu Q, Gong W, Ju S, Fan J, Gao X, Liu X, Lei X, Liu S, Ming X, Wang Q, Fu M, Song Y, Wang Y, Zhan Q
Signal transduction and targeted therapy 2024 Sep 26;9(1):253
Signal transduction and targeted therapy 2024 Sep 26;9(1):253
Novel Insights Into DLAT's Role in Alzheimer's Disease-Related Copper Toxicity Through Microglial Exosome Dynamics.
Ma X, Sun Y, Li C, Wang M, Zang Q, Zhang X, Wang F, Niu Y, Hua J
CNS neuroscience & therapeutics 2024 Oct;30(10):e70064
CNS neuroscience & therapeutics 2024 Oct;30(10):e70064
Exosomes Derived from Rejuvenated Stem Cells Inactivate NLRP3 Inflammasome and Pyroptosis of Nucleus Pulposus Cells via the Transfer of Antioxidants.
Peng S, Liu X, Chang L, Liu B, Zhang M, Mao Y, Shen X
Tissue engineering and regenerative medicine 2024 Oct;21(7):1061-1077
Tissue engineering and regenerative medicine 2024 Oct;21(7):1061-1077
Exosomal Src from hypoxic vascular smooth muscle cells exacerbates ischemic brain injury by promoting M1 microglial polarization.
Zhang X, Guo J, Liu J, Liu J, Li Z, Chen J, Jiang J, Zhang K, Zhou B
Neurochemistry international 2024 Oct;179:105819
Neurochemistry international 2024 Oct;179:105819
Small RNAs in plasma extracellular vesicles define biomarkers of premanifest changes in Huntington's disease.
Herrero-Lorenzo M, Pérez-Pérez J, Escaramís G, Martínez-Horta S, Pérez-González R, Rivas-Asensio E, Kulisevsky J, Gámez-Valero A, Martí E
Journal of extracellular vesicles 2024 Oct;13(10):e12522
Journal of extracellular vesicles 2024 Oct;13(10):e12522
Proteomic Profiling of Serum Extracellular Vesicles Identifies Diagnostic Signatures and Therapeutic Targets in Breast Cancer.
Xu G, Huang R, Wumaier R, Lyu J, Huang M, Zhang Y, Chen Q, Liu W, Tao M, Li J, Tao Z, Yu B, Xu E, Wang L, Yu G, Gires O, Zhou L, Zhu W, Ding C, Wang H
Cancer research 2024 Oct 1;84(19):3267-3285
Cancer research 2024 Oct 1;84(19):3267-3285
Neuroserpin and Extracellular Vesicles in Ischemic Stroke: Partners in Neuroprotection?
Brenna S, Glatzel M, Magnus T, Puig B, Galliciotti G
Aging and disease 2024 Oct 1;15(5):2191-2204
Aging and disease 2024 Oct 1;15(5):2191-2204
Glycoengineered extracellular vesicles released from antibacterial hydrogel facilitate diabetic wound healing by promoting angiogenesis.
Wang K, He Q, Yang M, Qiao Q, Chen J, Song J, Zang N, Hu H, Xia L, Xiang Y, Yan F, Hou X, Chen L
Journal of extracellular vesicles 2024 Nov;13(11):e70013
Journal of extracellular vesicles 2024 Nov;13(11):e70013
α-Synuclein species in plasma neuron-derived extracellular vesicles as biomarkers for iRBD.
Wang X, Zheng Y, Cai H, Kou W, Yang C, Li S, Zhu B, Wu J, Zhang N, Feng T, Li X, Xiao F, Yu Z
Annals of clinical and translational neurology 2024 Nov;11(11):2891-2903
Annals of clinical and translational neurology 2024 Nov;11(11):2891-2903
Barcoding of small extracellular vesicles with CRISPR-gRNA enables comprehensive, subpopulation-specific analysis of their biogenesis and release regulators.
Kunitake K, Mizuno T, Hattori K, Oneyama C, Kamiya M, Ota S, Urano Y, Kojima R
Nature communications 2024 Nov 19;15(1):9777
Nature communications 2024 Nov 19;15(1):9777
Exosomal lncRNA Mir100hg derived from cancer stem cells enhance glycolysis and promote metastasis of melanoma through miR-16-5p and miR-23a-3p.
Tan J, Tang Y, Li B, Shi L, Zhang Y, Chen Y, Chen Y, Li J, Xiang M, Zhou Y, Xing HR, Wang J
Experimental cell research 2024 Nov 1;443(1):114319
Experimental cell research 2024 Nov 1;443(1):114319
Exposure to micron-grade silica particles triggers pulmonary fibrosis through cell-to-cell delivery of exosomal miR-107.
Xia J, Wang D, Guo W, Pei Y, Zhang L, Bao L, Li Y, Qu Y, Zhao Y, Hao C, Yao W
International journal of biological macromolecules 2024 May;266(Pt 1):131058
International journal of biological macromolecules 2024 May;266(Pt 1):131058
circCDK13-loaded small extracellular vesicles accelerate healing in preclinical diabetic wound models.
Huang Q, Chu Z, Wang Z, Li Q, Meng S, Lu Y, Ma K, Cui S, Hu W, Zhang W, Wei Q, Qu Y, Li H, Fu X, Zhang C
Nature communications 2024 May 9;15(1):3904
Nature communications 2024 May 9;15(1):3904
Irradiated microparticles suppress prostate cancer by tumor microenvironment reprogramming and ferroptosis.
Deng Z, Li B, Yang M, Lu L, Shi X, Lovell JF, Zeng X, Hu W, Jin H
Journal of nanobiotechnology 2024 May 5;22(1):225
Journal of nanobiotechnology 2024 May 5;22(1):225
ANXA3-Rich Exosomes Derived from Tumor-Associated Macrophages Regulate Ferroptosis and Lymphatic Metastasis of Laryngeal Squamous Cell Carcinoma.
Xu L, Li W, Liu D, Cao J, Ge J, Liu X, Wang Y, Teng Y, Liu P, Guo X, He C, Liu M, Tian L
Cancer immunology research 2024 May 2;12(5):614-630
Cancer immunology research 2024 May 2;12(5):614-630
Novel lncRNA Gm33149 modulates metastatic heterogeneity in melanoma by regulating the miR-5623-3p/Wnt axis via exosomal transfer.
Chen Y, Zhang YH, Li J, Shi L, Xie JC, Han X, Chen YT, Xiang M, Li BW, Xing HR, Wang JY
Cancer gene therapy 2024 Mar;31(3):364-375
Cancer gene therapy 2024 Mar;31(3):364-375
Rab3a attenuates spinal cord injury by mediating vesicle release.
Yang Y, Liu Z, Lu Y, Yu X, Zhu R, Cai X, Lin J, Wang Z, Zha D
Brain research bulletin 2024 Mar;208:110884
Brain research bulletin 2024 Mar;208:110884
ALIX and TSG101 are essential for cellular entry and replication of two porcine alphacoronaviruses.
Chen X, Liang Y, Weng Z, Hu C, Peng Y, Sun Y, Gao Q, Huang Z, Tang S, Gong L, Zhang G
PLoS pathogens 2024 Mar;20(3):e1012103
PLoS pathogens 2024 Mar;20(3):e1012103
The Combined Anti-Aging Effect of Hydrolyzed Collagen Oligopeptides and Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells on Human Skin Fibroblasts.
Zhu H, Guo X, Zhang Y, Khan A, Pang Y, Song H, Zhao H, Liu Z, Qiao H, Xie J
Molecules (Basel, Switzerland) 2024 Mar 26;29(7)
Molecules (Basel, Switzerland) 2024 Mar 26;29(7)
A technique for repeated blood and cerebrospinal fluid sampling from individual rats over time without the need for repeated anesthesia.
Santandrea E, Aliakbari F, Truscott E, McCaig L, Donison NS, Graham D, Strong MJ, Volkening K
Scientific reports 2024 Mar 2;14(1):5171
Scientific reports 2024 Mar 2;14(1):5171
Isolation and characterization of small extracellular vesicles from murine primary mammary tumor.
Hu S, Zhang X, Yan W
STAR protocols 2024 Mar 15;5(1):102783
STAR protocols 2024 Mar 15;5(1):102783
Neutrophil-derived nanovesicles deliver IL-37 to mitigate renal ischemia-reperfusion injury via endothelial cell targeting.
Ma W, Wu D, Long C, Liu J, Xu L, Zhou L, Dou Q, Ge Y, Zhou C, Jia R
Journal of controlled release : official journal of the Controlled Release Society 2024 Jun;370:66-81
Journal of controlled release : official journal of the Controlled Release Society 2024 Jun;370:66-81
Plasma exosomes from patients with active thyroid-associated orbitopathy induce inflammation and fibrosis in orbital fibroblasts.
Wei L, Huang Q, Tu Y, Song S, Zhang X, Yu B, Liu Y, Li Z, Huang Q, Chen L, Liu B, Xu S, Li T, Liu X, Hu X, Liu W, Chi ZL, Wu W
Journal of translational medicine 2024 Jun 7;22(1):546
Journal of translational medicine 2024 Jun 7;22(1):546
M2 macrophage-derived exosomes promote angiogenesis and improve cardiac function after myocardial infarction.
Guo H, Li Z, Xiao B, Huang R
Biology direct 2024 Jun 6;19(1):43
Biology direct 2024 Jun 6;19(1):43
Activation of the Wnt/β-catenin signalling pathway enhances exosome production by hucMSCs and improves their capability to promote diabetic wound healing.
Wang L, Chen J, Song J, Xiang Y, Yang M, Xia L, Yang J, Hou X, Chen L, Wang L
Journal of nanobiotechnology 2024 Jun 26;22(1):373
Journal of nanobiotechnology 2024 Jun 26;22(1):373
Macrophage Phenotype Induced by Circulating Small Extracellular Vesicles from Women with Endometriosis.
Martínez-Zamora MA, Armengol-Badia O, Quintas-Marquès L, Carmona F, Closa D
Biomolecules 2024 Jun 21;14(7)
Biomolecules 2024 Jun 21;14(7)
Magnetic Particle Imaging Reveals that Iron-Labeled Extracellular Vesicles Accumulate in Brains of Mice with Metastases.
Toomajian VA, Tundo A, Ural EE, Greeson EM, Contag CH, Makela AV
ACS applied materials & interfaces 2024 Jun 19;16(24):30860-30873
ACS applied materials & interfaces 2024 Jun 19;16(24):30860-30873
Functionally improved mesenchymal stem cells via nanosecond pulsed electric fields for better treatment of osteoarthritis.
Lin J, Li K, Yang Z, Cao F, Gao L, Ning T, Xing D, Zeng H, Liu Q, Ge Z, Lin J
Journal of orthopaedic translation 2024 Jul;47:235-248
Journal of orthopaedic translation 2024 Jul;47:235-248
Baohuoside I chemosensitises breast cancer to paclitaxel by suppressing extracellular vesicle/CXCL1 signal released from apoptotic cells.
Wang S, Li J, Xu S, Wang N, Pan B, Yang B, Zheng Y, Zhang J, Peng F, Peng C, Wang Z
Journal of extracellular vesicles 2024 Jul;13(7):e12493
Journal of extracellular vesicles 2024 Jul;13(7):e12493
Optimized AF4 combined with density cushion ultracentrifugation enables profiling of high-purity human blood extracellular vesicles.
Hu L, Zheng X, Zhou M, Wang J, Tong L, Dong M, Xu T, Li Z
Journal of extracellular vesicles 2024 Jul;13(7):e12470
Journal of extracellular vesicles 2024 Jul;13(7):e12470
Multiscale photocatalytic proximity labeling reveals cell surface neighbors on and between cells.
Lin Z, Schaefer K, Lui I, Yao Z, Fossati A, Swaney DL, Palar A, Sali A, Wells JA
Science (New York, N.Y.) 2024 Jul 19;385(6706):eadl5763
Science (New York, N.Y.) 2024 Jul 19;385(6706):eadl5763
Regulated secretion of mutant p53 negatively affects T lymphocytes in the tumor microenvironment.
Dong X, Li C, Deng C, Liu J, Li D, Zhou T, Yang X, Liu Y, Guo Q, Feng Y, Yu Y, Wang Z, Guo W, Zhang S, Cui H, Jiang C, Wang X, Song X, Sun X, Cao L
Oncogene 2024 Jan;43(2):92-105
Oncogene 2024 Jan;43(2):92-105
A novel lung cancer stem cell extracellular vesicles lncRNA ROLLCSC modulate non-stemness cancer cell plasticity through miR-5623-3p and miR-217-5p targeting lipid metabolism.
Zhang YH, Chen Y, Shi L, Han X, Xie JC, Chen Y, Xiang M, Li BW, Li J, Xing HR, Wang JY
International journal of biological macromolecules 2024 Jan;256(Pt 2):128412
International journal of biological macromolecules 2024 Jan;256(Pt 2):128412
miRNA profiling of granulosa cell-derived exosomes reveals their role in promoting follicle development.
Zhou Q, Liu Z, Liao Z, Zhang Y, Qu M, Wu F, Tian J, Zhao H, Peng Q, Zheng W, Huang M, Yang S
Journal of cellular physiology 2024 Jan;239(1):20-35
Journal of cellular physiology 2024 Jan;239(1):20-35
Injectable Multifunctional Composite Hydrogel as a Combination Therapy for Preventing Postsurgical Adhesion.
Lv K, Lou P, Liu S, Wang Y, Yang J, Zhou P, Zhou X, Lu Y, Wang H, Cheng J, Liu J
Small (Weinheim an der Bergstrasse, Germany) 2024 Jan;20(1):e2303425
Small (Weinheim an der Bergstrasse, Germany) 2024 Jan;20(1):e2303425
M2 microglia-derived exosome-loaded electroconductive hydrogel for enhancing neurological recovery after spinal cord injury.
Guan P, Fan L, Zhu Z, Yang Q, Kang X, Li J, Zhang Z, Liu S, Liu C, Wang X, Xu J, Wang K, Sun Y
Journal of nanobiotechnology 2024 Jan 3;22(1):8
Journal of nanobiotechnology 2024 Jan 3;22(1):8
Tumour-associated macrophage-derived DOCK7-enriched extracellular vesicles drive tumour metastasis in colorectal cancer via the RAC1/ABCA1 axis.
Chen W, Zhou M, Guan B, Xie B, Liu Y, He J, Zhao J, Zhao Q, Yan D
Clinical and translational medicine 2024 Feb;14(2):e1591
Clinical and translational medicine 2024 Feb;14(2):e1591
Palmitoylation of vacuole membrane protein 1 promotes small extracellular vesicle secretion via interaction with ALIX and influences intercellular communication.
Qu M, Liu X, Wang X, Li Z, Zhou L, Li H
Cell communication and signaling : CCS 2024 Feb 26;22(1):150
Cell communication and signaling : CCS 2024 Feb 26;22(1):150
Nutrient availability regulates the secretion and function of immune cell-derived extracellular vesicles through metabolic rewiring.
Wang Y, Lou P, Xie Y, Liu S, Li L, Wang C, Du D, Chen Y, Lu Y, Cheng J, Liu J
Science advances 2024 Feb 16;10(7):eadj1290
Science advances 2024 Feb 16;10(7):eadj1290
Herpes simplex virus type 1 modifies the protein composition of extracellular vesicles to promote neurite outgrowth and neuroinfection.
Sun G, Kropp KA, Kirchner M, Plückebaum N, Selich A, Serrero M, Dhingra A, Cabrera JR, Ritter B, Bauerfeind R, Wyler E, Landthaler M, Schambach A, Sodeik B, Mertins P, Viejo-Borbolla A
mBio 2024 Feb 14;15(2):e0330823
mBio 2024 Feb 14;15(2):e0330823
Exosomes From Human Umbilical Cord Stem Cells Suppress Macrophage-to-myofibroblast Transition, Alleviating Renal Fibrosis.
Guo Q, Li P, Chen M, Yu Y, Wan Y, Zhang Z, Ren C, Shen L, Liu X, He D, Zhang Y, Wei G, Zhang D
Inflammation 2024 Dec;47(6):2094-2107
Inflammation 2024 Dec;47(6):2094-2107
Novel injectable adhesive hydrogel loaded with exosomes for holistic repair of hemophilic articular cartilage defect.
Yang Q, Liu G, Chen G, Chen G, Chen K, Fan L, Tu Y, Chen J, Shi Z, Chen C, Liu S, Deng G, Deng X, Sun C, Li X, Yang S, Zheng S, Chen B
Bioactive materials 2024 Dec;42:85-111
Bioactive materials 2024 Dec;42:85-111
The Microenvironment in an Experimental Model of Acute Pancreatitis Can Modify the Formation of the Protein Corona of sEVs, with Implications on Their Biological Function.
Armengol-Badia O, Maggi J, Casal C, Cortés R, Abián J, Carrascal M, Closa D
International journal of molecular sciences 2024 Dec 2;25(23)
International journal of molecular sciences 2024 Dec 2;25(23)
Fish Snx27 promotes viral products by modulating the innate immune response and exosomal machinery.
Yu Y, Liu J, Zhao Z, Lan X, Li L, Hu J, Zang Y-a, Zhang X, Chen J
Journal of virology 2024 Dec 17;98(12):e0097424
Journal of virology 2024 Dec 17;98(12):e0097424
Ectopic endometrial stromal cell-derived extracellular vesicles encapsulating microRNA-25-3p induce endometrial collagen I deposition impairing decidualization in endometriosis.
Zhu Y, Zheng B, Zhang Y, Li M, Jiang Y, Zhou J, Zhang Y, Kang N, Wu M, Yan Y, Xing J, Zhou J
Molecular human reproduction 2024 Dec 11;30(12)
Molecular human reproduction 2024 Dec 11;30(12)
Crucial roles of exosomes secreted from ganglioside GD3/GD2-positive glioma cells in enhancement of the malignant phenotypes and signals of GD3/GD2-negative glioma cells.
Hasnat MA, Ohmi Y, Yesmin F, Kambe M, Kawamoto Y, Bhuiyan RH, Mizutani M, Hashimoto N, Tsuchida A, Ohkawa Y, Kaneko K, Tajima O, Furukawa K, Furukawa K
Nagoya journal of medical science 2024 Aug;86(3):435-451
Nagoya journal of medical science 2024 Aug;86(3):435-451
Exosomes loaded a smart bilayer-hydrogel scaffold with ROS-scavenging and macrophage-reprogramming properties for repairing cartilage defect.
Lu X, Dai S, Huang B, Li S, Wang P, Zhao Z, Li X, Li N, Wen J, Sun Y, Man Z, Liu B, Li W
Bioactive materials 2024 Aug;38:137-153
Bioactive materials 2024 Aug;38:137-153
Extracellular vesicles miR-31-5p promotes pancreatic cancer chemoresistance via regulating LATS2-Hippo pathway and promoting SPARC secretion from pancreatic stellate cells.
Qin C, Zhao B, Wang Y, Li Z, Li T, Zhao Y, Wang W, Zhao Y
Journal of extracellular vesicles 2024 Aug;13(8):e12488
Journal of extracellular vesicles 2024 Aug;13(8):e12488
3D-hUMSCs Exosomes Ameliorate Vitiligo by Simultaneously Potentiating Treg Cells-Mediated Immunosuppression and Suppressing Oxidative Stress-Induced Melanocyte Damage.
Wang Q, Guo W, Niu L, Zhou Y, Wang Z, Chen J, Chen J, Ma J, Zhang J, Jiang Z, Wang B, Zhang Z, Li C, Jian Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(31):e2404064
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(31):e2404064
Nicotinamide metabolism face-off between macrophages and fibroblasts manipulates the microenvironment in gastric cancer.
Jiang Y, Wang Y, Chen G, Sun F, Wu Q, Huang Q, Zeng D, Qiu W, Wang J, Yao Z, Liang B, Li S, Wu J, Huang N, Wang Y, Chen J, Zhai X, Huang L, Xu B, Yamamoto M, Tsukamoto T, Nomura S, Liao W, Shi M
Cell metabolism 2024 Aug 6;36(8):1806-1822.e11
Cell metabolism 2024 Aug 6;36(8):1806-1822.e11
Identification of energy metabolism anomalies and serum biomarkers in the progression of premature ovarian failure via extracellular vesicles' proteomic and metabolomic profiles.
Liu Z, Zhou Q, He L, Liao Z, Cha Y, Zhao H, Zheng W, Lu D, Yang S
Reproductive biology and endocrinology : RB&E 2024 Aug 19;22(1):104
Reproductive biology and endocrinology : RB&E 2024 Aug 19;22(1):104
Activated STING-containing R-EVs from iPSC-derived MSCs promote antitumor immunity.
Qian L, Zhang Z, Zhang R, Zheng X, Xiao B, Zhang X, Wu Y, Chen Y, Zhang X, Zhou P, Fu Q, Kang T, Gao Y
Cancer letters 2024 Aug 10;597:217081
Cancer letters 2024 Aug 10;597:217081
BMSC-derived Exosomes Ameliorate Peritoneal Dialysis-associated Peritoneal Fibrosis via the Mir-27a-3p/TP53 Pathway.
Zhao JL, Zhao L, Zhan QN, Liu M, Zhang T, Chu WW
Current medical science 2024 Apr;44(2):333-345
Current medical science 2024 Apr;44(2):333-345
Chemotherapy-elicited extracellular vesicle CXCL1 from dying cells promotes triple-negative breast cancer metastasis by activating TAM/PD-L1 signaling.
Wang S, Li J, Hong S, Wang N, Xu S, Yang B, Zheng Y, Zhang J, Pan B, Hu Y, Wang Z
Journal of experimental & clinical cancer research : CR 2024 Apr 23;43(1):121
Journal of experimental & clinical cancer research : CR 2024 Apr 23;43(1):121
Human umbilical cord mesenchymal stem cell-derived exosomes ameliorate renal fibrosis in diabetic nephropathy by targeting Hedgehog/SMO signaling.
Zhang K, Zheng S, Wu J, He J, Ouyang Y, Ao C, Lang R, Jiang Y, Yang Y, Xiao H, Li Y, Li M, Wang H, Li C, Wu D
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Apr 15;38(7):e23599
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Apr 15;38(7):e23599
Insights into the function of ESCRT complex and LBPA in ASFV infection.
Barrado-Gil L, García-Dorival I, Galindo I, Alonso C, Cuesta-Geijo MÁ
Frontiers in cellular and infection microbiology 2023;13:1163569
Frontiers in cellular and infection microbiology 2023;13:1163569
Ferroptosis-dependent breast cancer cell-derived exosomes inhibit migration and invasion of breast cancer cells by suppressing M2 macrophage polarization.
Yi C, Wu S, Duan Q, Liu L, Li L, Luo Y, Wang A
PeerJ 2023;11:e15060
PeerJ 2023;11:e15060
The iron chelator deferriferrichrysin induces paraptosis via extracellular signal-related kinase activation in cancer cells.
Kinoshita N, Gessho M, Torii T, Ashida Y, Akamatsu M, Guo AK, Lee S, Katsuno T, Nakajima W, Budirahardja Y, Miyoshi D, Todokoro T, Ishida H, Nishikata T, Kawauchi K
Genes to cells : devoted to molecular & cellular mechanisms 2023 Sep;28(9):653-662
Genes to cells : devoted to molecular & cellular mechanisms 2023 Sep;28(9):653-662
Pancreatic stellate cell-derived exosomal tRF-19-PNR8YPJZ promotes proliferation and mobility of pancreatic cancer through AXIN2.
Cao W, Dai S, Ruan W, Long T, Zeng Z, Lei S
Journal of cellular and molecular medicine 2023 Sep;27(17):2533-2546
Journal of cellular and molecular medicine 2023 Sep;27(17):2533-2546
Follicular fluid derived exosomal miR-4449 regulates cell proliferation and oxidative stress by targeting KEAP1 in human granulosa cell lines KGN and COV434.
Wang M, Sun Y, Yuan D, Yue S, Yang Z
Experimental cell research 2023 Sep 15;430(2):113735
Experimental cell research 2023 Sep 15;430(2):113735
Extracellular Vesicle MicroRNAs From Corneal Stromal Stem Cell Enhance Stemness of Limbal Epithelial Stem Cells by Targeting the Notch Pathway.
Wang L, Xu X, Chen Q, Wei Y, Wei Z, Jin ZB, Liang Q
Investigative ophthalmology & visual science 2023 Sep 1;64(12):42
Investigative ophthalmology & visual science 2023 Sep 1;64(12):42
TRIM16-mediated lysophagy suppresses high-glucose-accumulated neuronal Aβ.
Chae CW, Yoon JH, Lim JR, Park JY, Cho JH, Jung YH, Choi GE, Lee HJ, Han HJ
Autophagy 2023 Oct;19(10):2752-2768
Autophagy 2023 Oct;19(10):2752-2768
TiO(2) nanoparticles promote tumor metastasis by eliciting pro-metastatic extracellular vesicles.
Mu X, Hu K, Wei A, Bai J, Feng L, Jiang J
Journal of nanobiotechnology 2023 Oct 27;21(1):392
Journal of nanobiotechnology 2023 Oct 27;21(1):392
Nanotopographical Cues Tune the Therapeutic Potential of Extracellular Vesicles for the Treatment of Aged Skeletal Muscle Injuries.
Wang K, Frey N, Garcia A, Man K, Yang Y, Gualerzi A, Clemens ZJ, Bedoni M, LeDuc PR, Ambrosio F
ACS nano 2023 Oct 24;17(20):19640-19651
ACS nano 2023 Oct 24;17(20):19640-19651
Stress granules plug and stabilize damaged endolysosomal membranes.
Bussi C, Mangiarotti A, Vanhille-Campos C, Aylan B, Pellegrino E, Athanasiadi N, Fearns A, Rodgers A, Franzmann TM, Šarić A, Dimova R, Gutierrez MG
Nature 2023 Nov;623(7989):1062-1069
Nature 2023 Nov;623(7989):1062-1069
GBP2 upregulated in LPS-stimulated macrophages-derived exosomes accelerates septic lung injury by activating epithelial cell NLRP3 signaling.
Huang W, Zhang Y, Zheng B, Ling X, Wang G, Li L, Wang W, Pan M, Li X, Meng Y
International immunopharmacology 2023 Nov;124(Pt B):111017
International immunopharmacology 2023 Nov;124(Pt B):111017
Autocrine role of senescent cardiac fibroblasts-derived extracellular vesicles.
Fujioka Y, Otani K, Kodama T, Okada M, Yamawaki H
The Journal of veterinary medical science 2023 Nov 2;85(11):1157-1164
The Journal of veterinary medical science 2023 Nov 2;85(11):1157-1164
SIRT2 regulates extracellular vesicle-mediated liver-bone communication.
Lin L, Guo Z, He E, Long X, Wang D, Zhang Y, Guo W, Wei Q, He W, Wu W, Li J, Wo L, Hong D, Zheng J, He M, Zhao Q
Nature metabolism 2023 May;5(5):821-841
Nature metabolism 2023 May;5(5):821-841
M2 Macrophage-Derived sEV Regulate Pro-Inflammatory CCR2(+) Macrophage Subpopulations to Favor Post-AMI Cardiac Repair.
Li L, Cao J, Li S, Cui T, Ni J, Zhang H, Zhu Y, Mao J, Gao X, Midgley AC, Zhu M, Fan G
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 May;10(14):e2202964
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 May;10(14):e2202964
Epsin1-mediated exosomal sorting of Dll4 modulates the tubular-macrophage crosstalk in diabetic nephropathy.
Liu JL, Zhang L, Huang Y, Li XH, Liu YF, Zhang SM, Zhao YE, Chen XJ, Liu Y, He LY, Dong Z, Liu FY, Sun L, Xiao L
Molecular therapy : the journal of the American Society of Gene Therapy 2023 May 3;31(5):1451-1467
Molecular therapy : the journal of the American Society of Gene Therapy 2023 May 3;31(5):1451-1467
ATG5 provides host protection acting as a switch in the atg8ylation cascade between autophagy and secretion.
Wang F, Peters R, Jia J, Mudd M, Salemi M, Allers L, Javed R, Duque TLA, Paddar MA, Trosdal ES, Phinney B, Deretic V
Developmental cell 2023 May 22;58(10):866-884.e8
Developmental cell 2023 May 22;58(10):866-884.e8
Canocapavir Is a Novel Capsid Assembly Modulator Inducing a Conformational Change of the Linker Region of HBV Core Protein.
Zheng Y, Yang L, Yu L, Zhu Y, Wu Y, Zhang Z, Xia T, Deng Q
Viruses 2023 May 18;15(5)
Viruses 2023 May 18;15(5)
SERS spectroscopy with machine learning to analyze human plasma derived sEVs for coronary artery disease diagnosis and prognosis.
Huang X, Liu B, Guo S, Guo W, Liao K, Hu G, Shi W, Kuss M, Duryee MJ, Anderson DR, Lu Y, Duan B
Bioengineering & translational medicine 2023 Mar;8(2):e10420
Bioengineering & translational medicine 2023 Mar;8(2):e10420
Extracellular vesicles from Zika virus-infected cells display viral E protein that binds ZIKV-neutralizing antibodies to prevent infection enhancement.
Zhao F, Xu Y, Liu N, Lv D, Chen Y, Liu Z, Jin X, Xiao M, Lavillette D, Zhong J, Bartenschlager R, Long G
The EMBO journal 2023 Mar 15;42(6):e112096
The EMBO journal 2023 Mar 15;42(6):e112096
Dendritic cell-derived exosomal miR-3064-5p inhibits SIRT6/PCSK9 to protect the blood-brain barrier after subarachnoid hemorrhage.
Wang Y, Zhang L, Lv L, Zhou Z, Xi H
Journal of biochemical and molecular toxicology 2023 Jun;37(6):e23346
Journal of biochemical and molecular toxicology 2023 Jun;37(6):e23346
Tanshinone IIA enhances the therapeutic efficacy of mesenchymal stem cells derived exosomes in myocardial ischemia/reperfusion injury via up-regulating miR-223-5p.
Li S, Yang K, Cao W, Guo R, Liu Z, Zhang J, Fan A, Huang Y, Ma C, Li L, Fan G
Journal of controlled release : official journal of the Controlled Release Society 2023 Jun;358:13-26
Journal of controlled release : official journal of the Controlled Release Society 2023 Jun;358:13-26
Autophagy and exosomes coordinately mediate quercetin's protective effects on alcoholic liver disease.
Chen H, Liu J, Peng S, Yang G, Cheng X, Chen L, Zhang H, Zhao Y, Yao P, Tang Y
The Journal of nutritional biochemistry 2023 Jun;116:109332
The Journal of nutritional biochemistry 2023 Jun;116:109332
EFFECT OF EXOSOMES DERIVED FROM BONE MARROW MESENCHYMAL STEM CELLS ON PROGRAMMED CELL DEATH IN BLAST-INDUCED LUNG INJURY IN RATS.
Deng M, He J, Hao C, Guo Y, Si H, Deng X, Zhang C, Li S, Yao S, Ren W, Yao W
Shock (Augusta, Ga.) 2023 Jun 1;59(6):955-965
Shock (Augusta, Ga.) 2023 Jun 1;59(6):955-965
BMSC-derived extracellular vesicles promoted osteogenesis via Axin2 inhibition by delivering MiR-16-5p.
Duan J, Li H, Wang C, Yao J, Jin Y, Zhao J, Zhang Y, Liu M, Sun H
International immunopharmacology 2023 Jul;120:110319
International immunopharmacology 2023 Jul;120:110319
Phospho-RNA-Seq Highlights Specific Small RNA Profiles in Plasma Extracellular Vesicles.
Solaguren-Beascoa M, Gámez-Valero A, Escaramís G, Herrero-Lorenzo M, Ortiz AM, Minguet C, Gonzalo R, Bravo MI, Costa M, Martí E
International journal of molecular sciences 2023 Jul 19;24(14)
International journal of molecular sciences 2023 Jul 19;24(14)
Single-cell transcriptome sequencing-based analysis: probing the mechanisms of glycoprotein NMB regulation of epithelial cells involved in silicosis.
Yang S, Sun Y, Long M, Zhou X, Yuan M, Yang L, Luo W, Cheng Y, Zhang X, Jiang W, Chao J
Particle and fibre toxicology 2023 Jul 19;20(1):29
Particle and fibre toxicology 2023 Jul 19;20(1):29
Extracellular vesicle-associated tyrosine kinase-like orphan receptors ROR1 and ROR2 promote breast cancer progression.
Irmer B, Efing J, Reitnauer LE, Angenendt A, Heinrichs S, Schubert A, Schulz M, Binder C, Tio J, Hansen U, Geyer C, Gerwing M, Bleckmann A, Menck K
Cell communication and signaling : CCS 2023 Jul 10;21(1):171
Cell communication and signaling : CCS 2023 Jul 10;21(1):171
Changes in urinary exosomal protein CALM1 may serve as an early noninvasive biomarker for diagnosing diabetic kidney disease.
Li T, Ci Liu T, Liu N, Zhang M
Clinica chimica acta; international journal of clinical chemistry 2023 Jul 1;547:117466
Clinica chimica acta; international journal of clinical chemistry 2023 Jul 1;547:117466
Macrophage-derived exosomal miR-195a-5p impairs tubular epithelial cells mitochondria in acute kidney injury mice.
Yuan L, Yang J, Liu F, Li L, Liu J, Chen Y, Cheng J, Lu Y, Yuan Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Jan;37(1):e22691
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Jan;37(1):e22691
Exosomal microRNA-4535 of Melanoma Stem Cells Promotes Metastasis by Inhibiting Autophagy Pathway.
Liu D, Li X, Zeng B, Zhao Q, Chen H, Zhang Y, Chen Y, Wang J, Xing HR
Stem cell reviews and reports 2023 Jan;19(1):155-169
Stem cell reviews and reports 2023 Jan;19(1):155-169
NAMPT encapsulated by extracellular vesicles from young adipose-derived mesenchymal stem cells treated tendinopathy in a "One-Stone-Two-Birds" manner.
Wu G, Su Q, Li J, Xue C, Zhu J, Cai Q, Huang J, Ji S, Cheng B, Ge H
Journal of nanobiotechnology 2023 Jan 5;21(1):7
Journal of nanobiotechnology 2023 Jan 5;21(1):7
Extracellular vesicles from mesenchymal stem cells reduce neuroinflammation in hippocampus and restore cognitive function in hyperammonemic rats.
Izquierdo-Altarejos P, Cabrera-Pastor A, Martínez-García M, Sánchez-Huertas C, Hernández A, Moreno-Manzano V, Felipo V
Journal of neuroinflammation 2023 Jan 2;20(1):1
Journal of neuroinflammation 2023 Jan 2;20(1):1
Manipulation of PD-L1 Endosomal Trafficking Promotes Anticancer Immunity.
Ye Z, Xiong Y, Peng W, Wei W, Huang L, Yue J, Zhang C, Lin G, Huang F, Zhang L, Zheng S, Yue J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Feb;10(6):e2206411
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Feb;10(6):e2206411
CLIC and membrane wound repair pathways enable pandemic norovirus entry and infection.
Ayyar BV, Ettayebi K, Salmen W, Karandikar UC, Neill FH, Tenge VR, Crawford SE, Bieberich E, Prasad BVV, Atmar RL, Estes MK
Nature communications 2023 Feb 28;14(1):1148
Nature communications 2023 Feb 28;14(1):1148
Extracellular vesicles released from macrophages modulates interleukin-1β in astrocytic and neuronal cells.
Kodidela S, Sinha N, Kumar A, Zhou L, Godse S, Kumar S
Scientific reports 2023 Feb 21;13(1):3005
Scientific reports 2023 Feb 21;13(1):3005
Human umbilical cord mesenchymal stem cell exosomes alleviate acute kidney injury by inhibiting pyroptosis in rats and NRK-52E cells.
Wan Y, Yu Y, Yu C, Luo J, Wen S, Shen L, Wei G, Hua Y
Renal failure 2023 Dec;45(1):2221138
Renal failure 2023 Dec;45(1):2221138
Dual-engineered cartilage-targeting extracellular vesicles derived from mesenchymal stem cells enhance osteoarthritis treatment via miR-223/NLRP3/pyroptosis axis: Toward a precision therapy.
Liu W, Liu A, Li X, Sun Z, Sun Z, Liu Y, Wang G, Huang D, Xiong H, Yu S, Zhang X, Fan C
Bioactive materials 2023 Dec;30:169-183
Bioactive materials 2023 Dec;30:169-183
Ferritinophagy-mediated apoptosis and paraptosis induction involved MAPK and PI3K/AKT pathway in mechanism of an iron chelator.
Wang R, Li J, Fu Y, Li Y, Qi Y, Li C, Gao F, Li C
Biochemical pharmacology 2023 Dec;218:115874
Biochemical pharmacology 2023 Dec;218:115874
MiR-1246b, a novel miRNA molecule of extracellular vesicles in bronchoalveolar lavage fluid, promotes nodule growth through FGF14 in patients with lung cancer.
Huang J, Ding M, Lu Y, Xu L, Zhang Y, Han S, Zhu X, Li Y, Chen P
Cell death & disease 2023 Dec 1;14(12):789
Cell death & disease 2023 Dec 1;14(12):789
Glutamine metabolic microenvironment drives M2 macrophage polarization to mediate trastuzumab resistance in HER2-positive gastric cancer.
Hu X, Ma Z, Xu B, Li S, Yao Z, Liang B, Wang J, Liao W, Lin L, Wang C, Zheng S, Wu Q, Huang Q, Yu L, Wang F, Shi M
Cancer communications (London, England) 2023 Aug;43(8):909-937
Cancer communications (London, England) 2023 Aug;43(8):909-937
Exosomes-loaded electroconductive nerve dressing for nerve regeneration and pain relief against diabetic peripheral nerve injury.
Yang Q, Su S, Liu S, Yang S, Xu J, Zhong Y, Yang Y, Tian L, Tan Z, Wang J, Yu Z, Shi Z, Liang F
Bioactive materials 2023 Aug;26:194-215
Bioactive materials 2023 Aug;26:194-215
Prostate cancer cells synergistically defend against CD8(+) T cells by secreting exosomal PD-L1.
Li D, Zhou X, Xu W, Chen Y, Mu C, Zhao X, Yang T, Wang G, Wei L, Ma B
Cancer medicine 2023 Aug;12(15):16405-16415
Cancer medicine 2023 Aug;12(15):16405-16415
Exosomes Derived from Hypoxia-Cultured Human Adipose Stem Cells Alleviate Articular Chondrocyte Inflammaging and Post-Traumatic Osteoarthritis Progression.
Chang LH, Wu SC, Chen CH, Chen JW, Huang WC, Wu CW, Lin YS, Chen YJ, Chang JK, Ho ML
International journal of molecular sciences 2023 Aug 29;24(17)
International journal of molecular sciences 2023 Aug 29;24(17)
Tumor-derived exosomes orchestrate the microRNA-128-3p/ELF4/CDX2 axis to facilitate the growth and metastasis of gastric cancer via delivery of LINC01091.
Wang Q, Zhang C, Cao S, Zhao H, Jiang R, Li Y
Cell biology and toxicology 2023 Apr;39(2):519-536
Cell biology and toxicology 2023 Apr;39(2):519-536
Chitosan Nerve Grafts Incorporated with SKP-SC-EVs Induce Peripheral Nerve Regeneration.
Zhou X, Yu M, Chen D, Deng C, Zhang Q, Gu X, Ding F
Tissue engineering and regenerative medicine 2023 Apr;20(2):309-322
Tissue engineering and regenerative medicine 2023 Apr;20(2):309-322
Exosomal lipid PI4P regulates small extracellular vesicle secretion by modulating intraluminal vesicle formation.
Jin X, Xia T, Luo S, Zhang Y, Xia Y, Yin H
Journal of extracellular vesicles 2023 Apr;12(4):e12319
Journal of extracellular vesicles 2023 Apr;12(4):e12319
Characterizing the differential distribution and targets of Sumo1 and Sumo2 in the mouse brain.
Suk TR, Nguyen TT, Fisk ZA, Mitkovski M, Geertsma HM, Parmasad JA, Heer MM, Callaghan SM, Benseler F, Brose N, Tirard M, Rousseaux MWC
iScience 2023 Apr 21;26(4):106350
iScience 2023 Apr 21;26(4):106350
Rejuvenation of tendon stem/progenitor cells for functional tendon regeneration through platelet-derived exosomes loaded with recombinant Yap1.
Lu J, Yang X, He C, Chen Y, Li C, Li S, Chen Y, Wu Y, Xiang Z, Kang J, Jiang G, Wang C, Diarra MD, He R, Feng G, Yan R
Acta biomaterialia 2023 Apr 15;161:80-99
Acta biomaterialia 2023 Apr 15;161:80-99
LncRNA H19-rich extracellular vesicles derived from gastric cancer stem cells facilitate tumorigenicity and metastasis via mediating intratumor communication network.
Zhao H, Jiang R, Zhang C, Feng Z, Wang X
Journal of translational medicine 2023 Apr 1;21(1):238
Journal of translational medicine 2023 Apr 1;21(1):238
Exosomes Derived from Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation through the Wnt3a/β-Catenin Signaling Pathway.
Li J, Zhao B, Dai Y, Zhang X, Chen Y, Wu X
Oxidative medicine and cellular longevity 2022;2022:9042345
Oxidative medicine and cellular longevity 2022;2022:9042345
Proteomic Profiling and Functional Analysis of B Cell-Derived Exosomes upon Pneumocystis Infection.
Ma D, Zhang QY, Rong HM, Zhai K, Tong ZH
Journal of immunology research 2022;2022:5187166
Journal of immunology research 2022;2022:5187166
Macrophages with Different Polarization Phenotypes Influence Cementoblast Mineralization through Exosomes.
Zhao Y, Huang Y, Liu H, Tan K, Wang R, Jia L, Li W
Stem cells international 2022;2022:4185972
Stem cells international 2022;2022:4185972
Hypoxic pancreatic cancer derived exosomal miR-30b-5p promotes tumor angiogenesis by inhibiting GJA1 expression.
Chen K, Wang Q, Liu X, Wang F, Yang Y, Tian X
International journal of biological sciences 2022;18(3):1220-1237
International journal of biological sciences 2022;18(3):1220-1237
Extracellular vesicle-associated microRNA-30b-5p activates macrophages through the SIRT1/ NF-κB pathway in cell senescence.
Xiao Y, Liang J, Witwer KW, Zhang Y, Wang Q, Yin H
Frontiers in immunology 2022;13:955175
Frontiers in immunology 2022;13:955175
Extracellular Vesicle-Mediated Delivery of Ultrasmall Superparamagnetic Iron Oxide Nanoparticles to Mice Brain.
Kutchy NA, Ma R, Liu Y, Buch S, Hu G
Frontiers in pharmacology 2022;13:819516
Frontiers in pharmacology 2022;13:819516
Exosomal miR-7002-5p derived from highglucose-induced macrophages suppresses autophagy in tubular epithelial cells by targeting Atg9b.
Zhao J, Chen J, Zhu W, Qi XM, Wu YG
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Sep;36(9):e22501
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Sep;36(9):e22501
Peritoneal M2 macrophage-derived extracellular vesicles as natural multitarget nanotherapeutics to attenuate cytokine storms after severe infections.
Wang Y, Liu S, Li L, Li L, Zhou X, Wan M, Lou P, Zhao M, Lv K, Yuan Y, Chen Y, Lu Y, Cheng J, Liu J
Journal of controlled release : official journal of the Controlled Release Society 2022 Sep;349:118-132
Journal of controlled release : official journal of the Controlled Release Society 2022 Sep;349:118-132
Injectable cartilage matrix hydrogel loaded with cartilage endplate stem cells engineered to release exosomes for non-invasive treatment of intervertebral disc degeneration.
Luo L, Gong J, Wang Z, Liu Y, Cao J, Qin J, Zuo R, Zhang H, Wang S, Zhao P, Yang D, Zhang M, Wang Y, Zhang J, Zhou Y, Li C, Ni B, Tian Z, Liu M
Bioactive materials 2022 Sep;15:29-43
Bioactive materials 2022 Sep;15:29-43
Extracellular vesicle fusion visualized by cryo-electron microscopy.
Morandi MI, Busko P, Ozer-Partuk E, Khan S, Zarfati G, Elbaz-Alon Y, Abou Karam P, Napso Shogan T, Ginini L, Gil Z, Regev-Rudzki N, Avinoam O
PNAS nexus 2022 Sep;1(4):pgac156
PNAS nexus 2022 Sep;1(4):pgac156
Vasorin-containing small extracellular vesicles retard intervertebral disc degeneration utilizing an injectable thermoresponsive delivery system.
Liao Z, Ke W, Liu H, Tong B, Wang K, Feng X, Hua W, Wang B, Song Y, Luo R, Liang H, Zhang W, Zhao K, Li S, Yang C
Journal of nanobiotechnology 2022 Sep 19;20(1):420
Journal of nanobiotechnology 2022 Sep 19;20(1):420
Elaiophylin triggers paraptosis and preferentially kills ovarian cancer drug-resistant cells by inducing MAPK hyperactivation.
Li GN, Zhao XJ, Wang Z, Luo MS, Shi SN, Yan DM, Li HY, Liu JH, Yang Y, Tan JH, Zhang ZY, Chen RQ, Lai HL, Huang XY, Zhou JF, Ma D, Fang Y, Gao QL
Signal transduction and targeted therapy 2022 Sep 12;7(1):317
Signal transduction and targeted therapy 2022 Sep 12;7(1):317
Neural stem cell‑derived exosomes transfer miR‑124‑3p into cells to inhibit glioma growth by targeting FLOT2.
Qian C, Wang Y, Ji Y, Chen D, Wang C, Zhang G, Wang Y
International journal of oncology 2022 Oct;61(4)
International journal of oncology 2022 Oct;61(4)
Exosomes Derived from Bone Marrow Mesenchymal Stem Cells Alleviate Ischemia-Reperfusion Injury and Promote Survival of Skin Flaps in Rats.
Niu Q, Yang Y, Li D, Guo W, Wang C, Xu H, Feng Z, Han Z
Life (Basel, Switzerland) 2022 Oct 9;12(10)
Life (Basel, Switzerland) 2022 Oct 9;12(10)
Extracellular vesicles microRNA-592 of melanoma stem cells promotes metastasis through activation of MAPK/ERK signaling pathway by targeting PTPN7 in non-stemness melanoma cells.
Zhang Y, Chen Y, Shi L, Li J, Wan W, Li B, Liu D, Li X, Chen Y, Xiang M, Chen H, Zeng B, Xing HR, Wang J
Cell death discovery 2022 Oct 27;8(1):428
Cell death discovery 2022 Oct 27;8(1):428
Melanoma stem cells promote metastasis via exosomal miR-1268a inactivation of autophagy.
Li X, Liu D, Chen H, Zeng B, Zhao Q, Zhang Y, Chen Y, Wang J, Xing HR
Biological research 2022 Oct 1;55(1):29
Biological research 2022 Oct 1;55(1):29
Cancer-derived exosomal circ_0038138 enhances glycolysis, growth, and metastasis of gastric adenocarcinoma via the miR-198/EZH2 axis.
Zheng Y, Li P, Ma J, Yang C, Dai S, Zhao C
Translational oncology 2022 Nov;25:101479
Translational oncology 2022 Nov;25:101479
HBV induced the discharge of intrinsic antiviral miRNAs in HBV-replicating hepatocytes via extracellular vesicles to facilitate its replication.
Chu Q, Li J, Chen J, Yuan Z
The Journal of general virology 2022 May;103(5)
The Journal of general virology 2022 May;103(5)
Multiplexed mRNA analysis of brain-derived extracellular vesicles upon experimental stroke in mice reveals increased mRNA content with potential relevance to inflammation and recovery processes.
Bub A, Brenna S, Alawi M, Kügler P, Gui Y, Kretz O, Altmeppen H, Magnus T, Puig B
Cellular and molecular life sciences : CMLS 2022 May 31;79(6):329
Cellular and molecular life sciences : CMLS 2022 May 31;79(6):329
Exosomes-derived miR-125-5p from cartilage endplate stem cells regulates autophagy and ECM metabolism in nucleus pulposus by targeting SUV38H1.
Chen D, Jiang X
Experimental cell research 2022 May 1;414(1):113066
Experimental cell research 2022 May 1;414(1):113066
In Vitro and In Vivo Analysis of Extracellular Vesicle-Mediated Metastasis Using a Bright, Red-Shifted Bioluminescent Reporter Protein.
Perez GI, Broadbent D, Zarea AA, Dolgikh B, Bernard MP, Withrow A, McGill A, Toomajian V, Thampy LK, Harkema J, Walker JR, Kirkland TA, Bachmann MH, Schmidt J, Kanada M
Advanced genetics (Hoboken, N.J.) 2022 Mar;3(1):2100055
Advanced genetics (Hoboken, N.J.) 2022 Mar;3(1):2100055
Thioredoxin upregulation delays diabetes-induced photoreceptor cell degeneration via AMPK-mediated autophagy and exosome secretion.
Ren X, Lv J, Wang N, Liu J, Gao C, Wu X, Yu Y, Teng Q, Dong W, Kong H, Kong L
Diabetes research and clinical practice 2022 Mar;185:109788
Diabetes research and clinical practice 2022 Mar;185:109788
Bladder Cancer Extracellular Vesicles Elicit a CD8 T Cell-Mediated Antitumor Immunity.
Ortiz-Bonilla CJ, Uccello TP, Gerber SA, Lord EM, Messing EM, Lee YF
International journal of molecular sciences 2022 Mar 8;23(6)
International journal of molecular sciences 2022 Mar 8;23(6)
Serum exosomal proteomics analysis of lung adenocarcinoma to discover new tumor markers.
Liu S, Tian W, Ma Y, Li J, Yang J, Li B
BMC cancer 2022 Mar 15;22(1):279
BMC cancer 2022 Mar 15;22(1):279
Recruitment of DNA to tumor-derived microvesicles.
Clancy JW, Sheehan CS, Boomgarden AC, D'Souza-Schorey C
Cell reports 2022 Mar 1;38(9):110443
Cell reports 2022 Mar 1;38(9):110443
Enhancement of Osteoblast Function through Extracellular Vesicles Derived from Adipose-Derived Stem Cells.
Ho ML, Hsu CJ, Wu CW, Chang LH, Chen JW, Chen CH, Huang KC, Chang JK, Wu SC, Shao PL
Biomedicines 2022 Jul 21;10(7)
Biomedicines 2022 Jul 21;10(7)
Extracellular vesicles derived from human umbilical cord mesenchymal stem cells alleviate osteoarthritis of the knee in mice model by interacting with METTL3 to reduce m6A of NLRP3 in macrophage.
Zhou H, Shen X, Yan C, Xiong W, Ma Z, Tan Z, Wang J, Li Y, Liu J, Duan A, Liu F
Stem cell research & therapy 2022 Jul 16;13(1):322
Stem cell research & therapy 2022 Jul 16;13(1):322
Tsc2 mutation induces renal tubular cell nonautonomous disease.
Kumar P, Zadjali F, Yao Y, Johnson D, Siroky B, Astrinidis A, Vogel P, Gross KW, Bissler JJ
Genes & diseases 2022 Jan;9(1):187-200
Genes & diseases 2022 Jan;9(1):187-200
Inflammatory capacity of exosomes released in the early stages of acute pancreatitis predicts the severity of the disease.
Carrascal M, Areny-Balagueró A, de-Madaria E, Cárdenas-Jaén K, García-Rayado G, Rivera R, Martin Mateos RM, Pascual-Moreno I, Gironella M, Abian J, Closa D
The Journal of pathology 2022 Jan;256(1):83-92
The Journal of pathology 2022 Jan;256(1):83-92
In Vivo Visualized Tracking of Tumor-Derived Extracellular Vesicles Using CRISPR-Cas9 System.
Ye Y, Shi Q, Yang T, Xie F, Zhang X, Xu B, Fang J, Chen J, Zhang Y, Li J
Technology in cancer research & treatment 2022 Jan-Dec;21:15330338221085370
Technology in cancer research & treatment 2022 Jan-Dec;21:15330338221085370
A Dual-Reporter Platform for Screening Tumor-Targeted Extracellular Vesicles.
Kanada M, Linenfelser L, Cox E, Gilad AA
Pharmaceutics 2022 Feb 22;14(3)
Pharmaceutics 2022 Feb 22;14(3)
Tumor-derived extracellular vesicles confer 5-fluorouracil resistance in esophageal cancer via long noncoding RNA AC116025.2 delivery.
Zhang S, Liu S, Ren J, Zhang H, Chen S, Chen Y, Zhang S, Chen W, Xu C, Zhong S, Liu S, Lin C
Molecular carcinogenesis 2022 Dec;61(12):1177-1190
Molecular carcinogenesis 2022 Dec;61(12):1177-1190
Improving the circulation time and renal therapeutic potency of extracellular vesicles using an endogenous ligand binding strategy.
Liu S, Lv K, Wang Y, Lou P, Zhou P, Wang C, Li L, Liao G, Zhang Y, Chen Y, Cheng J, Lu Y, Liu J
Journal of controlled release : official journal of the Controlled Release Society 2022 Dec;352:1009-1023
Journal of controlled release : official journal of the Controlled Release Society 2022 Dec;352:1009-1023
Intercellular transfer of activated STING triggered by RAB22A-mediated non-canonical autophagy promotes antitumor immunity.
Gao Y, Zheng X, Chang B, Lin Y, Huang X, Wang W, Ding S, Zhan W, Wang S, Xiao B, Huo L, Yu Y, Chen Y, Gong R, Wu Y, Zhang R, Zhong L, Wang X, Chen Q, Gao S, Jiang Z, Wei D, Kang T
Cell research 2022 Dec;32(12):1086-1104
Cell research 2022 Dec;32(12):1086-1104
Effect of plasma-derived extracellular vesicles on angiogenesis and the ensuing proliferative diabetic retinopathy through a miR-30b-dependent mechanism.
Wang P, Li C, Deng Y, Yu Q, Meng X, Jiang T, Wang Q, Fu Y
Diabetology & metabolic syndrome 2022 Dec 10;14(1):188
Diabetology & metabolic syndrome 2022 Dec 10;14(1):188
Jianpi Huayu decoction inhibits the epithelial-mesenchymal transition of hepatocellular carcinoma cells by suppressing exosomal miR-23a-3p/Smad signaling.
Xie CF, Feng KL, Wang JN, Luo R, Fang CK, Zhang Y, Shen CP, Zhong C
Journal of ethnopharmacology 2022 Aug 10;294:115360
Journal of ethnopharmacology 2022 Aug 10;294:115360
Discovery of a Nur77-mediated cytoplasmic vacuolation and paraptosis inducer (4-PQBH) for the treatment of hepatocellular carcinoma.
Li B, Huang J, Liu J, He F, Wen F, Yang C, Wang W, Wu T, Zhao T, Yao J, Liu S, Qiu Y, Fang M, Zeng J, Wu Z
Bioorganic chemistry 2022 Apr;121:105651
Bioorganic chemistry 2022 Apr;121:105651
Low-metastatic melanoma cells acquire enhanced metastatic capability via exosomal transfer of miR-199a-1-5p from highly metastatic melanoma cells.
Zhao Q, Chen H, Li X, Zeng B, Sun Z, Liu D, Chen Y, Zhang Y, Rosie Xing H, Wang J
Cell death discovery 2022 Apr 9;8(1):188
Cell death discovery 2022 Apr 9;8(1):188
Tsc Gene Locus Disruption and Differences in Renal Epithelial Extracellular Vesicles.
Kumar P, Zadjali F, Yao Y, Siroky B, Astrinidis A, Gross KW, Bissler JJ
Frontiers in physiology 2021;12:630933
Frontiers in physiology 2021;12:630933
LncRNA FOXP4-AS1 Promotes Progression of Ewing Sarcoma and Is Associated With Immune Infiltrates.
Xiong J, Wu L, Huang L, Wu C, Liu Z, Deng W, Ma S, Zhou Z, Yu H, Cao K
Frontiers in oncology 2021;11:718876
Frontiers in oncology 2021;11:718876
Development of a novel RNAi therapy: Engineered miR-31 exosomes promoted the healing of diabetic wounds.
Huang J, Yu M, Yin W, Liang B, Li A, Li J, Li X, Zhao S, Liu F
Bioactive materials 2021 Sep;6(9):2841-2853
Bioactive materials 2021 Sep;6(9):2841-2853
Tumor Necrosis Factor-stimulated Gene-6 (TSG-6) Secreted by BMSCs Regulates Activated Astrocytes by Inhibiting NF-κB Signaling Pathway to Ameliorate Blood Brain Barrier Damage After Intracerebral Hemorrhage.
Tang B, Song M, Xie X, Le D, Tu Q, Wu X, Chen M
Neurochemical research 2021 Sep;46(9):2387-2402
Neurochemical research 2021 Sep;46(9):2387-2402
Human Adipose Mesenchymal Stem Cell-derived Exosomes Protect Mice from DSS-Induced Inflammatory Bowel Disease by Promoting Intestinal-stem-cell and Epithelial Regeneration.
Yu H, Yang X, Xiao X, Xu M, Yang Y, Xue C, Li X, Wang S, Zhao RC
Aging and disease 2021 Sep;12(6):1423-1437
Aging and disease 2021 Sep;12(6):1423-1437
A novel delivery nanobiotechnology: engineered miR-181b exosomes improved osteointegration by regulating macrophage polarization.
Liu W, Yu M, Chen F, Wang L, Ye C, Chen Q, Zhu Q, Xie D, Shao M, Yang L
Journal of nanobiotechnology 2021 Sep 7;19(1):269
Journal of nanobiotechnology 2021 Sep 7;19(1):269
Engineering Extracellular Vesicles Restore the Impaired Cellular Uptake and Attenuate Intervertebral Disc Degeneration.
Liao Z, Liu H, Ma L, Lei J, Tong B, Li G, Ke W, Wang K, Feng X, Hua W, Li S, Yang C
ACS nano 2021 Sep 28;15(9):14709-14724
ACS nano 2021 Sep 28;15(9):14709-14724
Macrophage exosomes transfer angiotensin II type 1 receptor to lung fibroblasts mediating bleomycin-induced pulmonary fibrosis.
Sun NN, Zhang Y, Huang WH, Zheng BJ, Jin SY, Li X, Meng Y
Chinese medical journal 2021 Sep 2;134(18):2175-2185
Chinese medical journal 2021 Sep 2;134(18):2175-2185
Neddylation of Coro1a determines the fate of multivesicular bodies and biogenesis of extracellular vesicles.
Fei X, Li Z, Yang D, Kong X, Lu X, Shen Y, Li X, Xie S, Wang J, Zhao Y, Sun Y, Zhang J, Ye Z, Wang J, Cai Z
Journal of extracellular vesicles 2021 Oct;10(12):e12153
Journal of extracellular vesicles 2021 Oct;10(12):e12153
Tenascin-C expression in the lymph node pre-metastatic niche in muscle-invasive bladder cancer.
Silvers CR, Messing EM, Miyamoto H, Lee YF
British journal of cancer 2021 Nov;125(10):1399-1407
British journal of cancer 2021 Nov;125(10):1399-1407
Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway.
Gao X, Wang Y, Lu F, Chen X, Yang D, Cao Y, Zhang W, Chen J, Zheng L, Wang G, Fu M, Ma L, Song Y, Zhan Q
Journal of extracellular vesicles 2021 Mar;10(5):e12060
Journal of extracellular vesicles 2021 Mar;10(5):e12060
Osteosarcoma-derived exosomal miR-501-3p promotes osteoclastogenesis and aggravates bone loss.
Lin L, Wang H, Guo W, He E, Huang K, Zhao Q
Cellular signalling 2021 Jun;82:109935
Cellular signalling 2021 Jun;82:109935
Extracellular vesicles derived from LPS-preconditioned human synovial mesenchymal stem cells inhibit extracellular matrix degradation and prevent osteoarthritis of the knee in a mouse model.
Duan A, Shen K, Li B, Li C, Zhou H, Kong R, Shao Y, Qin J, Yuan T, Ji J, Guo W, Wang X, Xue T, Li L, Huang X, Sun Y, Cai Z, Liu W, Liu F
Stem cell research & therapy 2021 Jul 28;12(1):427
Stem cell research & therapy 2021 Jul 28;12(1):427
TGF-β1-mediated exosomal lnc-MMP2-2 increases blood-brain barrier permeability via the miRNA-1207-5p/EPB41L5 axis to promote non-small cell lung cancer brain metastasis.
Wu D, Deng S, Li L, Liu T, Zhang T, Li J, Yu Y, Xu Y
Cell death & disease 2021 Jul 20;12(8):721
Cell death & disease 2021 Jul 20;12(8):721
SPP1 derived from silica-exposed macrophage exosomes triggers fibroblast transdifferentiation.
Huang R, Hao C, Wang D, Zhao Q, Li C, Wang C, Yao W
Toxicology and applied pharmacology 2021 Jul 1;422:115559
Toxicology and applied pharmacology 2021 Jul 1;422:115559
EVs Containing Host Restriction Factor IFITM3 Inhibited ZIKV Infection of Fetuses in Pregnant Mice through Trans-placenta Delivery.
Zou X, Yuan M, Zhang T, Zheng N, Wu Z
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Jan 6;29(1):176-190
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Jan 6;29(1):176-190
Neuronal extracellular vesicle derived miR-98 prevents salvageable neurons from microglial phagocytosis in acute ischemic stroke.
Yang J, Cao LL, Wang XP, Guo W, Guo RB, Sun YQ, Xue TF, Cai ZY, Ji J, Cheng H, Sun XL
Cell death & disease 2021 Jan 6;12(1):23
Cell death & disease 2021 Jan 6;12(1):23
Mesenchymal Stem Cell-Derived Extracellular Vesicles Attenuate Mitochondrial Damage and Inflammation by Stabilizing Mitochondrial DNA.
Zhao M, Liu S, Wang C, Wang Y, Wan M, Liu F, Gong M, Yuan Y, Chen Y, Cheng J, Lu Y, Liu J
ACS nano 2021 Jan 26;15(1):1519-1538
ACS nano 2021 Jan 26;15(1):1519-1538
RAB31 marks and controls an ESCRT-independent exosome pathway.
Wei D, Zhan W, Gao Y, Huang L, Gong R, Wang W, Zhang R, Wu Y, Gao S, Kang T
Cell research 2021 Feb;31(2):157-177
Cell research 2021 Feb;31(2):157-177
Hypoxic pancreatic stellate cell-derived exosomal mirnas promote proliferation and invasion of pancreatic cancer through the PTEN/AKT pathway.
Cao W, Zeng Z, He Z, Lei S
Aging 2021 Feb 26;13(5):7120-7132
Aging 2021 Feb 26;13(5):7120-7132
Characterization of pendrin in urinary extracellular vesicles in a rat model of aldosterone excess and in human primary aldosteronism.
Ochiai-Homma F, Kuribayashi-Okuma E, Tsurutani Y, Ishizawa K, Fujii W, Odajima K, Kawagoe M, Tomomitsu Y, Murakawa M, Asakawa S, Hirohama D, Nagura M, Arai S, Yamazaki O, Tamura Y, Fujigaki Y, Nishikawa T, Shibata S
Hypertension research : official journal of the Japanese Society of Hypertension 2021 Dec;44(12):1557-1567
Hypertension research : official journal of the Japanese Society of Hypertension 2021 Dec;44(12):1557-1567
Human umbilical vein endothelial cells derived-exosomes promote osteosarcoma cell stemness by activating Notch signaling pathway.
Yang J, Hu Y, Wang L, Sun X, Yu L, Guo W
Bioengineered 2021 Dec;12(2):11007-11017
Bioengineered 2021 Dec;12(2):11007-11017
Extracellular vesicles derived from lipoaspirate fluid promote fat graft survival.
Nie F, Ding P, Zhang C, Zhao Z, Bi H
Adipocyte 2021 Dec;10(1):293-309
Adipocyte 2021 Dec;10(1):293-309
Surface Nanosieving Polyether Sulfone Particles with Graphene Oxide Encapsulation for the Negative Isolation toward Extracellular Vesicles.
Li Y, Yang K, Yuan H, Zhang W, Sui Z, Wang N, Lin H, Zhang L, Zhang Y
Analytical chemistry 2021 Dec 21;93(50):16835-16844
Analytical chemistry 2021 Dec 21;93(50):16835-16844
ALG2 regulates type I interferon responses by inhibiting STING trafficking.
Ji W, Zhang L, Xu X, Liu X
Journal of cell science 2021 Dec 15;134(24)
Journal of cell science 2021 Dec 15;134(24)
Extracellular vesicles package dsDNA to aggravate Crohn's disease by activating the STING pathway.
Zhao F, Zheng T, Gong W, Wu J, Xie H, Li W, Zhang R, Liu P, Liu J, Wu X, Zhao Y, Ren J
Cell death & disease 2021 Aug 27;12(9):815
Cell death & disease 2021 Aug 27;12(9):815
Cartilage endplate stem cells inhibit intervertebral disc degeneration by releasing exosomes to nucleus pulposus cells to activate Akt/autophagy.
Luo L, Jian X, Sun H, Qin J, Wang Y, Zhang J, Shen Z, Yang D, Li C, Zhao P, Liu M, Tian Z, Zhou Y
Stem cells (Dayton, Ohio) 2021 Apr;39(4):467-481
Stem cells (Dayton, Ohio) 2021 Apr;39(4):467-481
The tissue origin effect of extracellular vesicles on cartilage and bone regeneration.
Li Q, Yu H, Sun M, Yang P, Hu X, Ao Y, Cheng J
Acta biomaterialia 2021 Apr 15;125:253-266
Acta biomaterialia 2021 Apr 15;125:253-266
Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles.
Jiang W, Ma P, Deng L, Liu Z, Wang X, Liu X, Long G
Journal of extracellular vesicles 2020;9(1):1716513
Journal of extracellular vesicles 2020;9(1):1716513
Similar Repair Effects of Human Placenta, Bone Marrow Mesenchymal Stem Cells, and Their Exosomes for Damaged SVOG Ovarian Granulosa Cells.
Chen S, Wang Y, Liao L, Meng L, Li J, Shi C, Han H, Zheng X, Shen H
Stem cells international 2020;2020:8861557
Stem cells international 2020;2020:8861557
Extracellular vesicle-mediated delivery of miR-101 inhibits lung metastasis in osteosarcoma.
Zhang K, Dong C, Chen M, Yang T, Wang X, Gao Y, Wang L, Wen Y, Chen G, Wang X, Yu X, Zhang Y, Wang P, Shang M, Han K, Zhou Y
Theranostics 2020;10(1):411-425
Theranostics 2020;10(1):411-425
Plasma Exosomal miRNA Expression Profile as Oxaliplatin-Based Chemoresistant Biomarkers in Colorectal Adenocarcinoma.
Han J, Sun W, Liu R, Zhou Z, Zhang H, Chen X, Ba Y
Frontiers in oncology 2020;10:1495
Frontiers in oncology 2020;10:1495
Bovine Milk Exosomes Affect Proliferation and Protect Macrophages against Cisplatin-Induced Cytotoxicity.
Matic S, D'Souza DH, Wu T, Pangloli P, Dia VP
Immunological investigations 2020 Oct;49(7):711-725
Immunological investigations 2020 Oct;49(7):711-725
Exosomes derived from TSG-6 modified mesenchymal stromal cells attenuate scar formation during wound healing.
Jiang L, Zhang Y, Liu T, Wang X, Wang H, Song H, Wang W
Biochimie 2020 Oct;177:40-49
Biochimie 2020 Oct;177:40-49
Profilin 2 promotes growth, metastasis, and angiogenesis of small cell lung cancer through cancer-derived exosomes.
Cao Q, Liu Y, Wu Y, Hu C, Sun L, Wang J, Li C, Guo M, Liu X, Lv J, Huo X, Yue J, Du X, Chen Z
Aging 2020 Nov 21;12(24):25981-25999
Aging 2020 Nov 21;12(24):25981-25999
Isolation of extracellular vesicles from intestinal tissue in a mouse model of intestinal ischemia/reperfusion injury.
Chen XD, Zhao J, Yan Z, Zhou BW, Huang WF, Liu WF, Li C, Liu KX
BioTechniques 2020 May;68(5):257-262
BioTechniques 2020 May;68(5):257-262
DNA Damage Regulates Senescence-Associated Extracellular Vesicle Release via the Ceramide Pathway to Prevent Excessive Inflammatory Responses.
Hitomi K, Okada R, Loo TM, Miyata K, Nakamura AJ, Takahashi A
International journal of molecular sciences 2020 May 25;21(10)
International journal of molecular sciences 2020 May 25;21(10)
Tuberous Sclerosis Complex Axis Controls Renal Extracellular Vesicle Production and Protein Content.
Zadjali F, Kumar P, Yao Y, Johnson D, Astrinidis A, Vogel P, Gross KW, Bissler JJ
International journal of molecular sciences 2020 Mar 3;21(5)
International journal of molecular sciences 2020 Mar 3;21(5)
The Late Domain of Prototype Foamy Virus Gag Facilitates Autophagic Clearance of Stress Granules by Promoting Amphisome Formation.
Zheng Y, Zhu G, Yan J, Tang Y, Han S, Yin J, Peng B, He X, Liu W
Journal of virology 2020 Mar 17;94(7)
Journal of virology 2020 Mar 17;94(7)
Extracellular vesicles transmitted miR-31-5p promotes sorafenib resistance by targeting MLH1 in renal cell carcinoma.
He J, He J, Min L, He Y, Guan H, Wang J, Peng X
International journal of cancer 2020 Feb 15;146(4):1052-1063
International journal of cancer 2020 Feb 15;146(4):1052-1063
Circulating exosomal small RNAs are promising non-invasive diagnostic biomarkers for gastric cancer.
Ge L, Zhang N, Li D, Wu Y, Wang H, Wang J
Journal of cellular and molecular medicine 2020 Dec;24(24):14502-14513
Journal of cellular and molecular medicine 2020 Dec;24(24):14502-14513
Exosome-mediated Hic-5 regulates proliferation and apoptosis of osteosarcoma via Wnt/β-catenin signal pathway.
Sha L, Ma D, Chen C
Aging 2020 Dec 13;12(23):23598-23608
Aging 2020 Dec 13;12(23):23598-23608
Endosomal membrane tension regulates ESCRT-III-dependent intra-lumenal vesicle formation.
Mercier V, Larios J, Molinard G, Goujon A, Matile S, Gruenberg J, Roux A
Nature cell biology 2020 Aug;22(8):947-959
Nature cell biology 2020 Aug;22(8):947-959
Human umbilical cord-derived mesenchymal stem cells prevent the progression of early diabetic nephropathy through inhibiting inflammation and fibrosis.
Xiang E, Han B, Zhang Q, Rao W, Wang Z, Chang C, Zhang Y, Tu C, Li C, Wu D
Stem cell research & therapy 2020 Aug 3;11(1):336
Stem cell research & therapy 2020 Aug 3;11(1):336
Exosomes derived from atorvastatin-pretreated MSC accelerate diabetic wound repair by enhancing angiogenesis via AKT/eNOS pathway.
Yu M, Liu W, Li J, Lu J, Lu H, Jia W, Liu F
Stem cell research & therapy 2020 Aug 12;11(1):350
Stem cell research & therapy 2020 Aug 12;11(1):350
KLF4-mediated upregulation of CD9 and CD81 suppresses hepatocellular carcinoma development via JNK signaling.
Li Y, Yu S, Li L, Chen J, Quan M, Li Q, Gao Y
Cell death & disease 2020 Apr 29;11(4):299
Cell death & disease 2020 Apr 29;11(4):299
Exosomal miR-125a-5p derived from silica-exposed macrophages induces fibroblast transdifferentiation.
Wang D, Hao C, Zhang L, Zhang J, Liu S, Li Y, Qu Y, Zhao Y, Huang R, Wei J, Yao W
Ecotoxicology and environmental safety 2020 Apr 1;192:110253
Ecotoxicology and environmental safety 2020 Apr 1;192:110253
Extracellular vesicles expressing a single-chain variable fragment of an HIV-1 specific antibody selectively target Env(+) tissues.
Zou X, Yuan M, Zhang T, Wei H, Xu S, Jiang N, Zheng N, Wu Z
Theranostics 2019;9(19):5657-5671
Theranostics 2019;9(19):5657-5671
Exosomes from mesenchymal stem cells modulate endoplasmic reticulum stress to protect against nucleus pulposus cell death and ameliorate intervertebral disc degeneration in vivo.
Liao Z, Luo R, Li G, Song Y, Zhan S, Zhao K, Hua W, Zhang Y, Wu X, Yang C
Theranostics 2019;9(14):4084-4100
Theranostics 2019;9(14):4084-4100
Cocktail Strategy Based on NK Cell-Derived Exosomes and Their Biomimetic Nanoparticles for Dual Tumor Therapy.
Wang G, Hu W, Chen H, Shou X, Ye T, Xu Y
Cancers 2019 Oct 14;11(10)
Cancers 2019 Oct 14;11(10)
O-GlcNAcylation of Thr(12)/Ser(56) in short-form O-GlcNAc transferase (sOGT) regulates its substrate selectivity.
Liu L, Li L, Ma C, Shi Y, Liu C, Xiao Z, Zhang Y, Tian F, Gao Y, Zhang J, Ying W, Wang PG, Zhang L
The Journal of biological chemistry 2019 Nov 8;294(45):16620-16633
The Journal of biological chemistry 2019 Nov 8;294(45):16620-16633
Exosomes derived from human CD34(+) stem cells transfected with miR-26a prevent glucocorticoid-induced osteonecrosis of the femoral head by promoting angiogenesis and osteogenesis.
Zuo R, Kong L, Wang M, Wang W, Xu J, Chai Y, Guan J, Kang Q
Stem cell research & therapy 2019 Nov 15;10(1):321
Stem cell research & therapy 2019 Nov 15;10(1):321
Ovarian cancer circulating extracelluar vesicles promote coagulation and have a potential in diagnosis: an iTRAQ based proteomic analysis.
Zhang W, Peng P, Ou X, Shen K, Wu X
BMC cancer 2019 Nov 12;19(1):1095
BMC cancer 2019 Nov 12;19(1):1095
Specific Decrease in B-Cell-Derived Extracellular Vesicles Enhances Post-Chemotherapeutic CD8(+) T Cell Responses.
Zhang F, Li R, Yang Y, Shi C, Shen Y, Lu C, Chen Y, Zhou W, Lin A, Yu L, Zhang W, Xue Z, Wang J, Cai Z
Immunity 2019 Mar 19;50(3):738-750.e7
Immunity 2019 Mar 19;50(3):738-750.e7
The circRNA circPTPRA suppresses epithelial-mesenchymal transitioning and metastasis of NSCLC cells by sponging miR-96-5p.
Wei S, Zheng Y, Jiang Y, Li X, Geng J, Shen Y, Li Q, Wang X, Zhao C, Chen Y, Qian Z, Zhou J, Li W
EBioMedicine 2019 Jun;44:182-193
EBioMedicine 2019 Jun;44:182-193
Cluster of Differentiation 46 Is the Major Receptor in Human Blood-Brain Barrier Endothelial Cells for Uptake of Exosomes Derived from Brain-Metastatic Melanoma Cells (SK-Mel-28).
Kuroda H, Tachikawa M, Yagi Y, Umetsu M, Nurdin A, Miyauchi E, Watanabe M, Uchida Y, Terasaki T
Molecular pharmaceutics 2019 Jan 7;16(1):292-304
Molecular pharmaceutics 2019 Jan 7;16(1):292-304
Microvesicle-Mediated Delivery of Minicircle DNA Results in Effective Gene-Directed Enzyme Prodrug Cancer Therapy.
Kanada M, Kim BD, Hardy JW, Ronald JA, Bachmann MH, Bernard MP, Perez GI, Zarea AA, Ge TJ, Withrow A, Ibrahim SA, Toomajian V, Gambhir SS, Paulmurugan R, Contag CH
Molecular cancer therapeutics 2019 Dec;18(12):2331-2342
Molecular cancer therapeutics 2019 Dec;18(12):2331-2342
Detection of exosomal tyrosine receptor kinase B as a potential biomarker in ovarian cancer.
Li W, Lu Y, Yu X, Yong M, Ma D, Gao Q
Journal of cellular biochemistry 2019 Apr;120(4):6361-6369
Journal of cellular biochemistry 2019 Apr;120(4):6361-6369
Modulation of calreticulin expression reveals a novel exosome-mediated mechanism of Z variant α(1)-antitrypsin disposal.
Khodayari N, Oshins R, Alli AA, Tuna KM, Holliday LS, Krotova K, Brantly M
The Journal of biological chemistry 2019 Apr 19;294(16):6240-6252
The Journal of biological chemistry 2019 Apr 19;294(16):6240-6252
Exosomes derived from breast cancer lung metastasis subpopulations promote tumor self-seeding.
Huang H, Zheng X, Cai C, Yao Z, Lu S, Meng X, Miao Y, He Z, Cai C, Zou F
Biochemical and biophysical research communications 2018 Sep 3;503(1):242-248
Biochemical and biophysical research communications 2018 Sep 3;503(1):242-248
TGF-β-mediated exosomal lnc-MMP2-2 regulates migration and invasion of lung cancer cells to the vasculature by promoting MMP2 expression.
Wu DM, Deng SH, Liu T, Han R, Zhang T, Xu Y
Cancer medicine 2018 Oct;7(10):5118-5129
Cancer medicine 2018 Oct;7(10):5118-5129
Mycobacterium tuberculosis Type VII Secretion System Effectors Differentially Impact the ESCRT Endomembrane Damage Response.
Mittal E, Skowyra ML, Uwase G, Tinaztepe E, Mehra A, Köster S, Hanson PI, Philips JA
mBio 2018 Nov 27;9(6)
mBio 2018 Nov 27;9(6)
CD8α(+)CD11c(+) Extracellular Vesicles in the Lungs Control Immune Homeostasis of the Respiratory Tract via TGF-β1 and IL-10.
Wan S, Wang S, Weng L, Zhang G, Lin Z, Fei X, Zhang F, Yang F, Wang J, Cai Z
Journal of immunology (Baltimore, Md. : 1950) 2018 Mar 1;200(5):1651-1660
Journal of immunology (Baltimore, Md. : 1950) 2018 Mar 1;200(5):1651-1660
Exosomes Induce Fibroblast Differentiation into Cancer-Associated Fibroblasts through TGFβ Signaling.
Ringuette Goulet C, Bernard G, Tremblay S, Chabaud S, Bolduc S, Pouliot F
Molecular cancer research : MCR 2018 Jul;16(7):1196-1204
Molecular cancer research : MCR 2018 Jul;16(7):1196-1204
Exosomes Exploit the Virus Entry Machinery and Pathway To Transmit Alpha Interferon-Induced Antiviral Activity.
Yao Z, Qiao Y, Li X, Chen J, Ding J, Bai L, Shen F, Shi B, Liu J, Peng L, Li J, Yuan Z
Journal of virology 2018 Dec 15;92(24)
Journal of virology 2018 Dec 15;92(24)
Circulating Exosomal miR-17-5p and miR-92a-3p Predict Pathologic Stage and Grade of Colorectal Cancer.
Fu F, Jiang W, Zhou L, Chen Z
Translational oncology 2018 Apr;11(2):221-232
Translational oncology 2018 Apr;11(2):221-232
Characterization of urinary extracellular vesicle proteins in muscle-invasive bladder cancer.
Silvers CR, Miyamoto H, Messing EM, Netto GJ, Lee YF
Oncotarget 2017 Oct 31;8(53):91199-91208
Oncotarget 2017 Oct 31;8(53):91199-91208
Monocyte-derived exosomes upon exposure to cigarette smoke condensate alter their characteristics and show protective effect against cytotoxicity and HIV-1 replication.
Haque S, Sinha N, Ranjit S, Midde NM, Kashanchi F, Kumar S
Scientific reports 2017 Nov 23;7(1):16120
Scientific reports 2017 Nov 23;7(1):16120
Exosomes maintain cellular homeostasis by excreting harmful DNA from cells.
Takahashi A, Okada R, Nagao K, Kawamata Y, Hanyu A, Yoshimoto S, Takasugi M, Watanabe S, Kanemaki MT, Obuse C, Hara E
Nature communications 2017 May 16;8:15287
Nature communications 2017 May 16;8:15287
REG3β modifies cell tumor function by impairing extracellular vesicle uptake.
Bonjoch L, Gironella M, Iovanna JL, Closa D
Scientific reports 2017 Jun 9;7(1):3143
Scientific reports 2017 Jun 9;7(1):3143
Small extracellular vesicles secreted from senescent cells promote cancer cell proliferation through EphA2.
Takasugi M, Okada R, Takahashi A, Virya Chen D, Watanabe S, Hara E
Nature communications 2017 Jun 6;8:15729
Nature communications 2017 Jun 6;8:15729
Motile hepatocellular carcinoma cells preferentially secret sugar metabolism regulatory proteins via exosomes.
Zhang J, Lu S, Zhou Y, Meng K, Chen Z, Cui Y, Shi Y, Wang T, He QY
Proteomics 2017 Jul;17(13-14)
Proteomics 2017 Jul;17(13-14)
Involvement of exosomes in lung inflammation associated with experimental acute pancreatitis.
Bonjoch L, Casas V, Carrascal M, Closa D
The Journal of pathology 2016 Oct;240(2):235-45
The Journal of pathology 2016 Oct;240(2):235-45
EpCAM-dependent extracellular vesicles from intestinal epithelial cells maintain intestinal tract immune balance.
Jiang L, Shen Y, Guo D, Yang D, Liu J, Fei X, Yang Y, Zhang B, Lin Z, Yang F, Wang X, Wang K, Wang J, Cai Z
Nature communications 2016 Oct 10;7:13045
Nature communications 2016 Oct 10;7:13045
Characterization of exosomes derived from ovarian cancer cells and normal ovarian epithelial cells by nanoparticle tracking analysis.
Zhang W, Peng P, Kuang Y, Yang J, Cao D, You Y, Shen K
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Mar;37(3):4213-21
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Mar;37(3):4213-21
Regulation of exosomes released from normal ovarian epithelial cells and ovarian cancer cells.
Zhang W, Yang J, Cao D, You Y, Shen K, Peng P
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Dec;37:15763–15771
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Dec;37:15763–15771
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K
Journal of proteomics 2013 Mar 27;80:171-82
Journal of proteomics 2013 Mar 27;80:171-82
Exosomes mediate the cell-to-cell transmission of IFN-α-induced antiviral activity.
Li J, Liu K, Liu Y, Xu Y, Zhang F, Yang H, Liu J, Pan T, Chen J, Wu M, Zhou X, Yuan Z
Nature immunology 2013 Aug;14(8):793-803
Nature immunology 2013 Aug;14(8):793-803
Functional polycystin-1 dosage governs autosomal dominant polycystic kidney disease severity.
Hopp K, Ward CJ, Hommerding CJ, Nasr SH, Tuan HF, Gainullin VG, Rossetti S, Torres VE, Harris PC
The Journal of clinical investigation 2012 Nov;122(11):4257-73
The Journal of clinical investigation 2012 Nov;122(11):4257-73
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 12422-1-AP(ALIX; AIP1 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using PDCD6IP antibody 12422-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PDCD6IP antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PDCD6IP. This antibody recognizes human,mouse,rat antigen. The PDCD6IP antibody has been validated for the following applications: ELISA, IF, IP, WB analysis.
