Tissue expression
Cell line expression

PDCD6IP

gene product
AIP1, Alix, Hp95 
This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15. [provided by RefSeq, Jan 2012]
More gene data

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396 antibodies from 39 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Proteintech Group
2 antibodies
Invitrogen Antibodies
21 antibodies
Novus Biologicals
49 antibodies
GeneTex
2 antibodies
OriGene
8 antibodies
Atlas Antibodies
1 antibody
antibodies-online
112 antibodies
Boster Biological Technology
3 antibodies
LifeSpan BioSciences, Inc.
64 antibodies
NovoPro Bioscience Inc.
3 antibodies
Cell Signaling Technology, Inc
3 antibodies
Abnova Corporation
7 antibodies
Acris Antibodies GmbH
5 antibodies
Cusabio Biotech Co., Ltd
2 antibodies
St John's Laboratory
4 antibodies
Abgent
2 antibodies
Bethyl Laboratories
2 antibodies
HUABIO Research
1 antibody
Wuhan Fine Biotech Co., Ltd.
1 antibody
Santa Cruz Biotechnology
1 antibody
BioLegend
3 antibodies
Biorbyt
11 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Affinity Biosciences
1 antibody
QED Bioscience
1 antibody
Aviva Systems Biology
5 antibodies
MyBioSource
3 antibodies
NSJ Bioreagents
1 antibody
MilliporeSigma / Merck KGaA
5 antibodies
Creative Biolabs
13 antibodies
United States Biological
28 antibodies
Abbexa
6 antibodies
RayBiotech, Inc.
1 antibody
SICGEN
1 antibody
Leading Biology
2 antibodies
EMD Millipore
1 antibody
ProSci
1 antibody
Creative Diagnostics
3 antibodies