PDCD6IP

gene product
AIP1, Alix, Hp95
This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15. [provided by RefSeq, Jan 2012]
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334 antibodies from 32 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
GeneTex
2 antibodies
antibodies-online
112 antibodies
Novus Biologicals
37 antibodies
Atlas Antibodies
1 antibody
Cell Signaling Technology, Inc
3 antibodies
Proteintech Group
1 antibody
NovoPro Bioscience Inc.
3 antibodies
Abnova Corporation
7 antibodies
Invitrogen Antibodies
3 antibodies
Acris Antibodies GmbH
5 antibodies
Abgent
2 antibodies
Bethyl Laboratories
2 antibodies
LifeSpan BioSciences, Inc.
59 antibodies
OriGene
7 antibodies
Santa Cruz Biotechnology
1 antibody
BioLegend
3 antibodies
Boster Biological Technology
3 antibodies
Biorbyt
10 antibodies
St John's Laboratory
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Affinity Biosciences
1 antibody
Creative Biolabs
12 antibodies
Aviva Systems Biology
5 antibodies
MyBioSource
3 antibodies
NSJ Bioreagents
1 antibody
Creative Diagnostics
3 antibodies
United States Biological
28 antibodies
RayBiotech, Inc.
1 antibody
Sigma-Aldrich
2 antibodies
EMD Millipore
1 antibody
ProSci
1 antibody