634504

PDCD6IP antibody from BioLegend
AIP1, Alix, Hp95

Antibody data

Product number
634504
Provider
BioLegend
Proper citation
BioLegend Cat#634504, RRID:AB_2565615
Product name
Alexa Fluor® 594 anti-Alix
Provider product page
BioLegend - 634504
Antibody type
Monoclonal
Antigen
Recombinant full-length human Alix protein
Description
Alix (ALG-2-interacting protein X) is an adaptor protein that was first described for its capacity to bind to the calcium-binding protein ALG-2, the expression of which seemed necessary for cell death. The predicted molecular weight is approximately 96 kD. Alix contains an N-terminal Bro1 domain and a C-terminal proline-rich domain (PRD). The PRD contains multiple polyproline motifs, which are potential docking sites for proteins containing SH3 domains, interact with multiple cellular Alix-binding partners that are involved in apoptotic induction, endosomal sorting, and endocytosis. The Bro1 domain interacts with CHMP4b, which is also involved in endosomal sorting.
Reactivity
Human, Mouse
Host
Mouse
Conjugate
Yellow dye
Antibody clone number
3A9
Vial size
100 µg
Concentration
0.5 mg/ml
Storage
2°C-8°C
Handling
Ambient RT
Provider Type Product Number
- No reagents -