orb67185

antibody from Biorbyt

Targeting: FBXW7 AGO, CDC4, FBW7, FBX30, FBXW6, FLJ11071, SEL-10, SEL10

Western blot (Data presented on provider website)

Antibody Data

Product number

orb67185

Provider

Biorbyt

Product name

FBW7 antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal to FBW7.F-box/WD repeat-containing protein 7 (FBXW7) is a substrate recognition component of a SCF(SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination andsubsequent proteasomal degradation of target proteins. FBXW7 probably recognizes and binds tophosphorylated target proteins. FBXW7 is involved in the degradation of cyclin-E, MYC, NOTCH1released notch intracellular domain (NICD), and probably PSEN1.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Vial size

100 ul

Storage

-20°C