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LearnMA5-26562
antibody from Invitrogen Antibodies
Targeting: FBXW7
AGO, CDC4, FBW7, FBX30, FBXW6, FLJ11071, SEL-10, SEL10
Western blot
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- Antibody Data
- Antigen structure
- References [1]
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- Validations
- Other assay [1]
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- Product number
- MA5-26562 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- FBXW7 Monoclonal Antibody (OTI6F5)
- Antibody type
- Monoclonal
- Antigen
- Recombinant protein fragment
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- OTI6F5
- Vial size
- 100 µL
- Concentration
- 1 mg/mL
- Storage
- -20° C, Avoid Freeze/Thaw Cycles
Submitted references Expression levels of FBXW7 and MDM2 E3 ubiquitin ligases and their c-Myc and p53 substrates in patients with dysplastic nevi or melanoma.
Mozuraitiene J, Gudleviciene Z, Vincerzevskiene I, Laurinaviciene A, Pamedys J
Oncology letters 2021 Jan;21(1):37
Oncology letters 2021 Jan;21(1):37
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Figure 2. FBXW7 protein expression in cutaneous melanoma. Representative images of (A) strong FBXW7 immunostaining in pT1 melanoma, (B) moderate FBXW7 immunostaining in pT2 melanoma, (C) weak FBXW7 staining in pT3 melanoma and (D) negative FBXW7 staining in pT4 melanoma. Marked areas indicate FBXW7 staining in malignant melanocytes. Magnification, x100. FBXW7, F-box and WD repeat domain-containing 7; pT, pathological tumor stage.
