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Learn28424-1-AP
antibody from Proteintech Group
Targeting: FBXW7
AGO, CDC4, FBW7, FBX30, FBXW6, FLJ11071, SEL-10, SEL10
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations [0]
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- Product number
- 28424-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- FBXW7 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated FBXW7 antibody (Cat. #28424-1-AP) is a rabbit polyclonal antibody that shows reactivity with Human, Mouse and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Autophagy Regulates VDAC3 Ubiquitination by FBXW7 to Promote Erastin-Induced Ferroptosis in Acute Lymphoblastic Leukemia.
Histone demethylase JMJD3 protects against renal fibrosis by suppressing TGFβ and Notch signaling and preserving PTEN expression.
Dihydrocapsaicin Inhibits Cell Proliferation and Metastasis in Melanoma via Down-regulating β-Catenin Pathway.
Aberrant FBXW7-mediated ubiquitination and degradation of ZMYND8 enhances tumor progression and stemness in bladder cancer.
Tazarotene-induced gene 1 interacts with Polo-like kinase 2 and inhibits cell proliferation in HCT116 colorectal cancer cells.
MicroRNA‑223‑induced inhibition of the FBXW7 gene affects the proliferation and apoptosis of colorectal cancer cells via the Notch and Akt/mTOR pathways.
Loss of FBXW7-mediated degradation of BRAF elicits resistance to BET inhibitors in adult T cell leukemia cells.
The 18S rRNA m6 A methyltransferase METTL5 promotes mouse embryonic stem cell differentiation.
Lycorine hydrochloride inhibits cell proliferation and induces apoptosis through promoting FBXW7-MCL1 axis in gastric cancer.
Fam83d modulates MAP kinase and AKT signaling and is induced during neurogenic skeletal muscle atrophy.
Long non-coding RNA SSTR5-AS1 facilitates gemcitabine resistance via stabilizing NONO in gallbladder carcinoma.
TRIP13 promotes the cell proliferation, migration and invasion of glioblastoma through the FBXW7/c-MYC axis.
Zhu T, Liu B, Wu D, Xu G, Fan Y
Frontiers in cell and developmental biology 2021;9:740884
Frontiers in cell and developmental biology 2021;9:740884
Histone demethylase JMJD3 protects against renal fibrosis by suppressing TGFβ and Notch signaling and preserving PTEN expression.
Yu C, Xiong C, Tang J, Hou X, Liu N, Bayliss G, Zhuang S
Theranostics 2021;11(6):2706-2721
Theranostics 2021;11(6):2706-2721
Dihydrocapsaicin Inhibits Cell Proliferation and Metastasis in Melanoma via Down-regulating β-Catenin Pathway.
Shi S, Li C, Zhang Y, Deng C, Liu W, Du J, Li Q, Ji Y, Guo L, Liu L, Hu H, Liu Y, Cui H
Frontiers in oncology 2021;11:648052
Frontiers in oncology 2021;11:648052
Aberrant FBXW7-mediated ubiquitination and degradation of ZMYND8 enhances tumor progression and stemness in bladder cancer.
Qiu F, Jin Y, Pu J, Huang Y, Hou J, Zhao X, Lu Y
Experimental cell research 2021 Oct 15;407(2):112807
Experimental cell research 2021 Oct 15;407(2):112807
Tazarotene-induced gene 1 interacts with Polo-like kinase 2 and inhibits cell proliferation in HCT116 colorectal cancer cells.
Wang CH, Lu TJ, Wang LK, Wu CC, Chen ML, Kuo CY, Shyu RY, Tsai FM
Cell biology international 2021 Nov;45(11):2347-2356
Cell biology international 2021 Nov;45(11):2347-2356
MicroRNA‑223‑induced inhibition of the FBXW7 gene affects the proliferation and apoptosis of colorectal cancer cells via the Notch and Akt/mTOR pathways.
Liu Z, Ma T, Duan J, Liu X, Liu L
Molecular medicine reports 2021 Feb;23(2)
Molecular medicine reports 2021 Feb;23(2)
Loss of FBXW7-mediated degradation of BRAF elicits resistance to BET inhibitors in adult T cell leukemia cells.
Yeh CH, Bellon M, Wang F, Zhang H, Fu L, Nicot C
Molecular cancer 2020 Sep 9;19(1):139
Molecular cancer 2020 Sep 9;19(1):139
The 18S rRNA m6 A methyltransferase METTL5 promotes mouse embryonic stem cell differentiation.
Xing M, Liu Q, Mao C, Zeng H, Zhang X, Zhao S, Chen L, Liu M, Shen B, Guo X, Ma H, Chen H, Zhang J
EMBO reports 2020 Oct 5;21(10):e49863
EMBO reports 2020 Oct 5;21(10):e49863
Lycorine hydrochloride inhibits cell proliferation and induces apoptosis through promoting FBXW7-MCL1 axis in gastric cancer.
Li C, Deng C, Pan G, Wang X, Zhang K, Dong Z, Zhao G, Tan M, Hu X, Shi S, Du J, Ji H, Wang X, Yang L, Cui H
Journal of experimental & clinical cancer research : CR 2020 Oct 30;39(1):230
Journal of experimental & clinical cancer research : CR 2020 Oct 30;39(1):230
Fam83d modulates MAP kinase and AKT signaling and is induced during neurogenic skeletal muscle atrophy.
Cooper LM, Hanson A, Kavanagh JA, Waddell DS
Cellular signalling 2020 Jun;70:109576
Cellular signalling 2020 Jun;70:109576
Long non-coding RNA SSTR5-AS1 facilitates gemcitabine resistance via stabilizing NONO in gallbladder carcinoma.
Xue Z, Yang B, Xu Q, Zhu X, Qin G
Biochemical and biophysical research communications 2020 Feb 19;522(4):952-959
Biochemical and biophysical research communications 2020 Feb 19;522(4):952-959
TRIP13 promotes the cell proliferation, migration and invasion of glioblastoma through the FBXW7/c-MYC axis.
Zhang G, Zhu Q, Fu G, Hou J, Hu X, Cao J, Peng W, Wang X, Chen F, Cui H
British journal of cancer 2019 Dec;121(12):1069-1078
British journal of cancer 2019 Dec;121(12):1069-1078
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