600-401-280
antibody from Rockland Immunochemicals, Inc.
Targeting: CHEK2
bA444G7, CDS1, CHK2, HuCds1, PP1425, RAD53
Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 600-401-280 - Provider product page
- Provider
- Rockland Immunochemicals, Inc.
- Proper citation
- Rockland Cat#600-401-280, RRID:AB_2276271
- Product name
- Anti-CHK2 pT68 (RABBIT) Antibody - 600-401-280
- Antibody type
- Polyclonal
- Vial size
- 100 µl
Submitted references Effect of caffeine on the ATR/Chk1 pathway in the epidermis of UVB-irradiated mice.
Lu YP, Lou YR, Peng QY, Xie JG, Nghiem P, Conney AH
Cancer research 2008 Apr 1;68(7):2523-9
Cancer research 2008 Apr 1;68(7):2523-9
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Supportive validation
- Submitted by
- Rockland Immunochemicals, Inc. (provider)
- Main image
- Experimental details
- Western blot using Rockland's Affinity Purified anti-Chk2 pT68 antibody shows detection of a predominant band at ~60 kDa corresponding to phosphorylated Chk2 (arrowhead) in MCF-7 whole cell lysates after treatment with doxorubicin. Chk2 phosphorylation was induced using increasing concentrations of the DNA damaging agent doxorubicin as indicated for 24 h prior to lysate production. Personal communication, Xiao HeYang, University of Oklahoma Health Sciences Center.
- Validation comment
- Western Blot