CLDN11

gene product
OSP, OTM
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this gene is a major component of central nervous system (CNS) myelin and plays an important role in regulating proliferation and migration of oligodendrocytes. Mouse studies showed that the gene deficiency results in deafness and loss of the Sertoli cell epithelial phenotype in the testis. This protein is a tight junction protein at the human blood-testis barrier (BTB), and the BTB disruption is related to a dysfunction of this gene. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2010]
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229 antibodies from 33 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Proteintech Group
1 antibody
NovoPro Bioscience Inc.
2 antibodies
Biorbyt
10 antibodies
antibodies-online
48 antibodies
Affinity Biosciences
3 antibodies
GeneTex
2 antibodies
Atlas Antibodies
1 antibody
Santa Cruz Biotechnology
1 antibody
LifeSpan BioSciences, Inc.
31 antibodies
Bioworld Technology, Inc
2 antibodies
OriGene
12 antibodies
Aviva Systems Biology
2 antibodies
Novus Biologicals
10 antibodies
Invitrogen Antibodies
5 antibodies
Boster Biological Technology
2 antibodies
St John's Laboratory
4 antibodies
Abbkine Scientific Co.Ltd.
2 antibodies
ProSci
2 antibodies
Acris Antibodies GmbH
5 antibodies
Abnova Corporation
4 antibodies
Arigo
2 antibodies
R&D Systems
8 antibodies
Creative Biolabs
3 antibodies
MyBioSource
4 antibodies
Creative Diagnostics
3 antibodies
United States Biological
38 antibodies
Spring Bioscience
4 antibodies
STEMCELL Technologies Inc
1 antibody
Sigma-Aldrich
2 antibodies
EMD Millipore
1 antibody
GenWay
1 antibody
RayBiotech, Inc.
1 antibody