Antibody data
- Antibody Data
- Antigen structure
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- Validations
- Western blot [1]
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- Product number
- BS8238 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- ERAF polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human ERAF.
- Description
- Ï«-hemoglobin stabilizing protein (AHSP), also designated erythroid associated factor (ERAF), is an erythroid-specific protein that acts as a chaperone to prevent the aggregation of Ï«-hemoglobin during normal erythroid cell development.It specifically protects free Ï«-hemoglobin from precipitation in live cells and in solution. It forms a heterodimer with free Ï«-hemoglobin, but not with ÉÇ-hemoglobin or hemoglobin A (Ï«2-ÉÇ-2). AHSP localizes to the cytoplasm and is expressed in the blood and bone marrow. The AHSP protein is downregulated in transmissible spongiform encephalopathies (TSEs). AHSP may regulate pathological states of Ï«-hemoglobin excess such as ÉÇ-thalassemia,a group of hereditary disorders involving the decreased production of normal adult hemoglobin (HbA) that are characterized by a deficiency in the synthesis of ÉÇ-globin chains.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
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- Experimental details
- WesternBlot (WB) analysis of ERAF polyclonal antibody