AHSP

This gene encodes a molecular chaperone which binds specifically to free alpha-globin and is involved in hemoglobin assembly. The encoded protein binds to monomeric alpha-globin until it has been transferred to beta-globin to form a heterodimer, which in turn binds to another heterodimer to form the stable tetrameric hemoglobin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

Description

Alpha hemoglobin stabilizing protein

Tissue specificity

Tissue enriched (bone marrow)

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Plasma proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

16:p11.2 (31527900 - 31528803)

Ensembl ID

ENSG00000169877  (ver. 103.38)

Orthologs

-

UniProt

Q9NZD4

neXtProt

NX_Q9NZD4

Human splice variants