SCN10A

The protein encoded by this gene is a tetrodotoxin-resistant voltage-gated sodium channel alpha subunit. The properties of the channel formed by the encoded transmembrane protein can be altered by interaction with different beta subunits. This protein may be involved in the onset of pain associated with peripheral neuropathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]

Description

sodium voltage-gated channel alpha subunit 10

Protein family

Disease related genes, FDA approved drug targets, Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Plasma proteins, Predicted membrane proteins, Voltage-gated ion channels

Chromosome

3:p22.2 (38696802 - 38816286)

Ensembl ID

ENSG00000185313  (ver. 98.38)

Orthologs

Mouse Scn10a: ENSMUSG00000034533

UniProt

Q9Y5Y9

neXtProt

NX_Q9Y5Y9

Human splice variants
Mouse splice variants