Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 11-3009 - Provider product page 
- Provider
- ABEOMICS Inc.
- Product name
- Anti-USP7 Antibody
- Antibody type
- Polyclonal
- Description
- USP7 (ubiquitin specific peptidase 7) is a deubiquitinating enzyme that prevents protein degradation by removing poly-ubiquitin chains from its substrates. It regulates stability of a number of human transcription factors and tumor suppressors and plays a critical role in the development of several types of cancer, including prostate and small cell lung cancer.USP7 regulates Pol-eta (DNA polymerase eta) stability through both indirect and direct mechanisms. It regulates the stability of the DNA maintenance methyltransferase. Diseases associated with USP7 include UV-sensitive syndrome.
- Reactivity
- Human
- Host
- Rabbit
- Antigen sequence
- A partial length recombinant USP7 p
 rotein (amino acids 932-1100) was u
 sed as the immunogen for this antib
 ody.
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
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					Supportive validation
					
									
				
		- Submitted by
- ABEOMICS Inc. (provider)
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- Experimental details
- Western blot analysis of USP7. Anti-USP7 antibody (11-3009) was used at 4 µg/ml on A431 lysate.