Tissue expression
Cell line expression
Protein structure
USP7
Ubiquitin specific peptidase 7HAUSP
The protein encoded by this gene belongs to the peptidase C19 family, which includes ubiquitinyl hydrolases. This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling), and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM27, involved in the respective process. Mutations in this gene have been implicated in a neurodevelopmental disorder. [provided by RefSeq, Mar 2016]
Top validated antibodies |
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Invitrogen Antibodies | PA5-34911 | 1 references | Polyclonal |
WB
ICC
IP
IHC
OA
|
|
GeneTex | GTX125894 | 2 references | Polyclonal |
WB
ICC
IP
IHC |
|
antibodies-online | ABIN151954 | 25 references | Polyclonal |
WB
ICC
IP
IHC |
|
Novus Biologicals | NB100-513 | 25 references | Polyclonal |
WB
IP
IHC
|
|
Proteintech Group | 66514-1-Ig | 3 references | Monoclonal |
WB
EL
ICC
IHC |
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Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider