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LearnMAB5871
antibody from Novus Biologicals
Targeting: TGFBR1
ACVRLK4, ALK-5, ALK5, ESS1, MSSE, TBR-i, TBRI
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations [0]
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- Product number
- MAB5871 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Rat Monoclonal TGF-beta RI/ALK-5 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human and mouse TGF-beta RI/ALK-5 in Western blots. In direct ELISAs and Western blots, this antibody shows no cross-reactivity with rrMIS RII, rhTGF-beta RII, rhTGF-beta RIIb, or rhTGF-beta RIII.
- Reactivity
- Human, Mouse
- Host
- Rat
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references Fibulin-6 regulates pro-fibrotic TGF-β responses in neonatal mouse ventricular cardiac fibroblasts.
Differential TGFβ pathway targeting by miR-122 in humans and mice affects liver cancer metastasis.
Dendritic cell SIRT1-HIF1α axis programs the differentiation of CD4+ T cells through IL-12 and TGF-β1.
Beclin 1 regulates neuronal transforming growth factor-β signaling by mediating recycling of the type I receptor ALK5.
Integrin alpha3beta1 potentiates TGFbeta-mediated induction of MMP-9 in immortalized keratinocytes.
Chowdhury A, Hasselbach L, Echtermeyer F, Jyotsana N, Theilmeier G, Herzog C
Scientific reports 2017 Feb 17;7:42725
Scientific reports 2017 Feb 17;7:42725
Differential TGFβ pathway targeting by miR-122 in humans and mice affects liver cancer metastasis.
Yin S, Fan Y, Zhang H, Zhao Z, Hao Y, Li J, Sun C, Yang J, Yang Z, Yang X, Lu J, Xi JJ
Nature communications 2016 Mar 18;7:11012
Nature communications 2016 Mar 18;7:11012
Dendritic cell SIRT1-HIF1α axis programs the differentiation of CD4+ T cells through IL-12 and TGF-β1.
Liu G, Bi Y, Xue L, Zhang Y, Yang H, Chen X, Lu Y, Zhang Z, Liu H, Wang X, Wang R, Chu Y, Yang R
Proceedings of the National Academy of Sciences of the United States of America 2015 Mar 3;112(9):E957-65
Proceedings of the National Academy of Sciences of the United States of America 2015 Mar 3;112(9):E957-65
Beclin 1 regulates neuronal transforming growth factor-β signaling by mediating recycling of the type I receptor ALK5.
O'Brien CE, Bonanno L, Zhang H, Wyss-Coray T
Molecular neurodegeneration 2015 Dec 21;10:69
Molecular neurodegeneration 2015 Dec 21;10:69
Integrin alpha3beta1 potentiates TGFbeta-mediated induction of MMP-9 in immortalized keratinocytes.
Lamar JM, Iyer V, DiPersio CM
The Journal of investigative dermatology 2008 Mar;128(3):575-86
The Journal of investigative dermatology 2008 Mar;128(3):575-86
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