Tissue expression
Cell line expression
TGFBR1
gene productACVRLK4, ALK-5, ALK5, ESS1, MSSE, TBR-i, TBRI
The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Featured antibodies
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4 references | Polyclonal |
WB
ICC IHC
FC |
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0 references | Polyclonal |
ICC
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