PAB3503
antibody from Abnova Corporation
Targeting: TGFBR1
ACVRLK4, ALK-5, ALK5, ESS1, MSSE, TBR-i, TBRI
Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- PAB3503 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB3503, RRID:AB_1581313
- Product name
- TGFBR1 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of TGFBR1.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Identification of cell surface targets through meta-analysis of microarray data.
Elucidation of Smad requirement in transforming growth factor-beta type I receptor-induced responses.
Functions of transforming growth factor-beta family type I receptors and Smad proteins in the hypertrophic maturation and osteoblastic differentiation of chondrocytes.
Hyaluronan promotes signaling interaction between CD44 and the transforming growth factor beta receptor I in metastatic breast tumor cells.
Haeberle H, Dudley JT, Liu JT, Butte AJ, Contag CH
Neoplasia (New York, N.Y.) 2012 Jul;14(7):666-9
Neoplasia (New York, N.Y.) 2012 Jul;14(7):666-9
Elucidation of Smad requirement in transforming growth factor-beta type I receptor-induced responses.
Itoh S, Thorikay M, Kowanetz M, Moustakas A, Itoh F, Heldin CH, ten Dijke P
The Journal of biological chemistry 2003 Feb 7;278(6):3751-61
The Journal of biological chemistry 2003 Feb 7;278(6):3751-61
Functions of transforming growth factor-beta family type I receptors and Smad proteins in the hypertrophic maturation and osteoblastic differentiation of chondrocytes.
Valcourt U, Gouttenoire J, Moustakas A, Herbage D, Mallein-Gerin F
The Journal of biological chemistry 2002 Sep 13;277(37):33545-58
The Journal of biological chemistry 2002 Sep 13;277(37):33545-58
Hyaluronan promotes signaling interaction between CD44 and the transforming growth factor beta receptor I in metastatic breast tumor cells.
Bourguignon LY, Singleton PA, Zhu H, Zhou B
The Journal of biological chemistry 2002 Oct 18;277(42):39703-12
The Journal of biological chemistry 2002 Oct 18;277(42):39703-12
No comments: Submit comment
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- The TGFBR1 polyclonal antibody (Cat # PAB3503) is used in Western blot to detect TGFBR1 in mouse small intestine tissue lysate.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with TGFBR1 polyclonal antibody (Cat # PAB3503) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)