BS5722

antibody from Bioworld Technology, Inc
Targeting: FZD6 Hfz6
Provider product page for BS5722
Western blot
Immunoprecipitation

Antibody data

Product number
BS5722 - Provider product page
Provider
Bioworld Technology, Inc
Product name
Frizzled 6 (T167) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 167-212 of Human Frizzled-6.
Description
Frizzled-6 (FZD6, also known as frizzled homolog 6 in Drosophila) is a seven-transmembrane domain receptor that binds the Wnt ligand and influences macroscopic hair patterning and other tissue polarity events. Frizzled-6 protein contains a signal peptide and a cysteine-rich domain (CRD) in the N-terminal extracellular region, and does not contain a C-terminal PDZ domain-binding motif. Frizzled-3 and frizzled-6 influence neural tube closure and the planar orientation of hair bundles on a subset of auditory and vestibular sensory cells. Madin-Darby canine kidney (MDCK) cells are competent to form tubules in vitro and express the frizzled-6 receptor, which is known to form a complex with Wnt-4 through the CRD in this cell type. Frizzled-6 is expressed as a 4.4 kb mRNA in various human tissues, including adult heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, thymus, prostate, testis, ovary, small intestine and colon.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
FZD6 protein structure - BS5722 shown in red.