FZD6

gene product
Hfz6
This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide. [provided by RefSeq, Aug 2011]
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308 antibodies from 31 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
R&D Systems
4 antibodies
Aviva Systems Biology
4 antibodies
antibodies-online
105 antibodies
OriGene
6 antibodies
Affinity Biosciences
1 antibody
Novus Biologicals
22 antibodies
Acris Antibodies GmbH
2 antibodies
Abnova Corporation
2 antibodies
Atlas Antibodies
1 antibody
LifeSpan BioSciences, Inc.
49 antibodies
Bioworld Technology, Inc
2 antibodies
Biorbyt
11 antibodies
GeneTex
7 antibodies
NovoPro Bioscience Inc.
3 antibodies
GenWay
2 antibodies
Cell Signaling Technology, Inc
1 antibody
Invitrogen Antibodies
7 antibodies
St John's Laboratory
3 antibodies
Abbkine Scientific Co.Ltd.
2 antibodies
RabMAbs
2 antibodies
Abgent
3 antibodies
Bethyl Laboratories
2 antibodies
United States Biological
42 antibodies
Abiocode, Inc.
1 antibody
MyBioSource
4 antibodies
Creative Diagnostics
3 antibodies
Sigma-Aldrich
1 antibody
RayBiotech, Inc.
2 antibodies
EMD Millipore
1 antibody
ProSci
1 antibody