Tissue expression
Cell line expression

SYNGAP1

gene product
KIAA1938, RASA5, SYNGAP 
This gene encodes a Ras GTPase activating protein that is a member of the N-methyl-D-aspartate receptor complex. The N-terminal domain of the protein contains a Ras-GAP domain, a pleckstrin homology domain, and a C2 domain that may be involved in binding of calcium and phospholipids. The C-terminal domain consists of a ten histidine repeat region, serine and tyrosine phosphorylation sites, and a T/SXV motif required for postsynaptic scaffold protein interaction. The encoded protein negatively regulates Ras, Rap and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor trafficking to the postsynaptic membrane to regulate synaptic plasticity and neuronal homeostasis. Allelic variants of this gene are associated with intellectual disability and autism spectrum disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]
More gene data

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248 antibodies from 34 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Proteintech Group
1 antibody
GeneTex
2 antibodies
Novus Biologicals
5 antibodies
Invitrogen Antibodies
6 antibodies
NovoPro Bioscience Inc.
2 antibodies
Cusabio Biotech Co., Ltd
5 antibodies
Boster Biological Technology
2 antibodies
HUABIO Research
1 antibody
Wuhan Fine Biotech Co., Ltd.
1 antibody
LifeSpan BioSciences, Inc.
12 antibodies
Atlas Antibodies
2 antibodies
antibodies-online
62 antibodies
Cell Signaling Technology, Inc
4 antibodies
Antibodies.com
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Affinity Biosciences
1 antibody
Acris Antibodies GmbH
2 antibodies
NSJ Bioreagents
2 antibodies
Biorbyt
12 antibodies
Abnova Corporation
4 antibodies
Abgent
4 antibodies
OriGene
2 antibodies
RabMAbs
2 antibodies
Aviva Systems Biology
1 antibody
ProSci
2 antibodies
MyBioSource
3 antibodies
United States Biological
51 antibodies
Everest Biotech
2 antibodies
EMD Millipore
2 antibodies
Leading Biology
4 antibodies
Abbexa
2 antibodies
Creative Diagnostics
1 antibody
Creative Biolabs
13 antibodies