Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Immunohistochemistry [1]
- Flow cytometry [2]
- Other assay [1]
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Validation data
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- Product number
- PA5-26138 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- OPRM1 Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide
- Description
- This antibody is predicted to react with porcine, non-human primate and rat based on sequence homology.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 400 µL
- Concentration
- 0.4 mg/mL
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Submitted references D,L-Methadone enhances the cytotoxic activity of standard chemotherapeutic agents on pediatric rhabdomyosarcoma.
Inhibition of mu-opioid receptor suppresses proliferation of hepatocellular carcinoma cells via CD147-p53-MAPK cascade signaling pathway.
Methadone-Not a magic bullet in melanoma therapy.
Urla C, Corteletti I, Raible AS, Handgretinger R, Fuchs J, Warmann SW, Schmid E
Journal of cancer research and clinical oncology 2022 Jun;148(6):1337-1350
Journal of cancer research and clinical oncology 2022 Jun;148(6):1337-1350
Inhibition of mu-opioid receptor suppresses proliferation of hepatocellular carcinoma cells via CD147-p53-MAPK cascade signaling pathway.
Zhang JJ, Song CG, Dai JM, Zhang XQ, Lin P, Li L, Yang XM, Chen ZN
American journal of translational research 2021;13(5):3967-3986
American journal of translational research 2021;13(5):3967-3986
Methadone-Not a magic bullet in melanoma therapy.
Brüggen MC, Mangana J, Irmisch A, French LE, Levesque MP, Cheng PF, Dummer R
Experimental dermatology 2018 Jun;27(6):694-696
Experimental dermatology 2018 Jun;27(6):694-696
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemistry analysis of OPRM1 in formalin fixed and paraffin embedded human brain tissue. Samples were incubated with OPRM1 polyclonal antibody (Product # PA5-26138) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Flow cytometry analysis of K562 cells using an OPRM1 polyclonal antibody (Product # PA5-26138) (bottom) compared to a negative control cell (top) at a dilution of 1:10-50, followed by a FITC-conjugated goat anti-rabbit antibody
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Flow cytometry of OPRM1 in K562 cells (bottom histogram). Samples were incubated with OPRM1 polyclonal antibody (Product # PA5-26138) followed by FITC-conjugated goat-anti-rabbit secondary antibody. Negative control cell (top histogram).
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- NULL