342402

antibody from BioLegend

Targeting: C5AR2 C5L2, GPR77

Flow cytometry

Antibody data

Submit

Validation data

Product number: 342402 - Provider product page
Provider: BioLegend
Proper citation: BioLegend Cat#342402, RRID:AB_2113254
Product name: Purified anti-human C5L2
Antibody type: Monoclonal
Antigen: C5L2
Description: C5L2 (C5a receptor-like 2) is a seven-transmembrane orphan receptor, also known as GPR77, which shares significant homology to C5a receptor (CD88). But it is a decoy receptor without G-protein coupling. C5L2 is co-expressed with C5aR on many kinds of cells, such as neutrophils, immature dendritic cells, mast cells, macrophages, and astrocytes. C5L2 binds C5a with similar high affinity as C5aR and relatively higher affinity for C5a-des-Arg than with C5aR. Clone 1D9-M12 is known to block C5a binding to C5L2, but does not react with C5a receptor.
Reactivity: Human
Host: Mouse
Conjugate: Unconjugated
Isotype: IgG
Vial size: 100 µg
Concentration: 0.5 mg/ml
Storage: The antibody solution should be stored undiluted at 4 °C.

C5AR2 protein structure - 342402 shown in red.