342404

antibody from BioLegend

Targeting: C5AR2 C5L2, GPR77

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

342404

Provider

BioLegend

Proper citation

BioLegend Cat#342404, RRID:AB_2247831

Product name

PE anti-human C5L2

Antibody type

Monoclonal

Antigen

C5L2

Description

C5L2 (C5a receptor-like 2) is a seven-transmembrane orphan receptor, also known as GPR77, which shares significant homology to C5a receptor (CD88). But it is a decoy receptor without G-protein coupling. C5L2 is co-expressed with C5aR on many kinds of cells, such as neutrophils, immature dendritic cells, mast cells, macrophages, and astrocytes. C5L2 binds C5a with similar high affinity as C5aR and relatively higher affinity for C5a-des-Arg than with C5aR. Clone 1D9-M12 is known to block C5a binding to C5L2, but does not react with C5a receptor.

Reactivity

Human

Host

Mouse

Conjugate

Yellow dye

Isotype

IgG

Vial size

100 tests

Storage

The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.