PA1-46151

antibody from Invitrogen Antibodies

Targeting: GRM1 GPRC1A, mGlu1, MGLUR1, PPP1R85

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Other assay (Supportive data in Antibodypedia)

Antibody Data

Product number

PA1-46151

Provider

Invitrogen Antibodies

Product name

mGluR1 Polyclonal Antibody

Antibody type

Polyclonal

Antigen

Synthetic peptide

Description

Suggested positive control: human brain lysate, rat dorsal root ganglion, and rat brain (cingulate cortex), antigen standard for GRIN1 (transient overexpression lysate).

Reactivity

Human, Mouse, Rat, Chicken/Avian

Host

Rabbit

Isotype

IgG

Vial size

100 µg

Concentration

1 mg/mL

Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

References

Submitted references

Differential Retinoic Acid Signaling in the Hippocampus of Aged Rats with and without Memory Impairment.

Wołoszynowska-Fraser MU, Rossi SL, Long JM, McCaffery PJ, Rapp PR
eNeuro 2021 Sep-Oct;8(5)

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Repeated Galvanic Vestibular Stimulation Modified the Neuronal Potential in the Vestibular Nucleus.

Kim G, Lee S, Kim KS
Neural plasticity 2020;2020:5743972

Other assay

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Figure 6. FMRP expression and cellular and dendritic expression of GluR1 in the hippocampus. Representative blots for proteins of interest ( A ), FMRP expression relative to GAPDH (bottom four panels); cellular GluR1 expression relative to beta-actin, and synaptosome GluR1 levels relative to PSD95 (top two panels); L stands for molecular ladder lane. Cytosolic fraction included as confirmation of the fractionation. Hippocampal expression of FMRP ( B , C ). Whole hippocampus ( D , E ) and synaptosome GluR1 protein levels ( G , H ). Correlation of cytosolic GluR1 protein expression with LI scores ( F ). Results shown as bars with individual animal data plotted. Statistical analysis, unpaired two-tailed Student's t test ( B , D , G ), one-way ANOVA, with Tukey's multiple comparisons test ( C , E , H ), and linear regression ( F ; all animals, gray line; aged animals, black line); C, cytosolic fraction; ** p < 0.01. Y n = 8 and aged n = 16 (AU n = 8, AI n = 8; B-F ); Y n = 5 and aged n = 15 (AU n = 7, AI n = 8; G , H ). Error bars represent SEM.