GRM1

gene product
GPRC1A, mGlu1, MGLUR1, PPP1R85
This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Validated within AVI
Eligible for validation within AVI
664 antibodies from 35 providers.

Antibody properties

General

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
antibodies-online
239 antibodies
Novus Biologicals
30 antibodies
Invitrogen Antibodies
12 antibodies
Cell Signaling Technology, Inc
1 antibody
Biorbyt
47 antibodies
GeneTex
6 antibodies
Enzo Life Sciences
3 antibodies
Proteintech Group
1 antibody
NovoPro Bioscience Inc.
9 antibodies
LifeSpan BioSciences, Inc.
87 antibodies
Abnova Corporation
11 antibodies
Affinity Biosciences
1 antibody
OriGene
16 antibodies
Aviva Systems Biology
3 antibodies
Bioworld Technology, Inc
2 antibodies
Acris Antibodies GmbH
14 antibodies
R&D Systems
5 antibodies
St John's Laboratory
5 antibodies
ProSci
3 antibodies
Arigo
4 antibodies
Creative Biolabs
20 antibodies
Abbexa
26 antibodies
Creative Diagnostics
8 antibodies
Atlas Antibodies
1 antibody
Spring Bioscience
8 antibodies
United States Biological
67 antibodies
GenWay
7 antibodies
RayBiotech, Inc.
5 antibodies
Abbiotec
1 antibody
Boster Biological Technology
1 antibody
MyBioSource
8 antibodies
EMD Millipore
3 antibodies
Sigma-Aldrich
3 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Abgent
6 antibodies