Tissue expression
Cell line expression
Protein structure
PTPN3
Protein tyrosine phosphatase non-receptor type 3PTPH1
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. P97, a cell cycle regulator involved in a variety of membrane related functions, has been shown to be a substrate of this PTP. This PTP was also found to interact with, and be regulated by adaptor protein 14-3-3 beta. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]
Top validated antibodies |
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Invitrogen Antibodies | PA5-15527 | 1 references | Polyclonal |
WB
IHC
OA
|
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Abnova Corporation | PAB4104 | 3 references | Polyclonal |
WB
IHC |
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LSBio | LS-C101002 | Polyclonal |
WB
IHC |
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Cusabio Biotech Co., Ltd | CSB-PA019040LA01HU | Polyclonal |
EL
ICC
IHC
|
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FineTest Biotech | FNab10135 | Polyclonal |
WB
EL
IHC
|
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