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- References [5]
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- Product number
- ABIN1449994 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Signal Peptide, CUB Domain, EGF-Like 3 (SCUBE3) (Middle Region) antibody
- Antibody type
- Polyclonal
- Antigen
- A 15 amino acid synthetic peptide near the center of Human SCUBE3
- Description
- Affinity chromatography purified via peptide column
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- Middle Region
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 1.0 mg/mL
- Storage
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references SCUBE3 is an endogenous TGF-β receptor ligand and regulates the epithelial-mesenchymal transition in lung cancer.
Transgenic overexpression of the secreted, extracellular EGF-CUB domain-containing protein SCUBE3 induces cardiac hypertrophy in mice.
A novel secreted, cell-surface glycoprotein containing multiple epidermal growth factor-like repeats and one CUB domain is highly expressed in primary osteoblasts and bones.
Prostaglandin E2 modulates the functional responsiveness of human monocytes to chemokines.
Identification of a novel family of cell-surface proteins expressed in human vascular endothelium.
Wu YY, Peck K, Chang YL, Pan SH, Cheng YF, Lin JC, Yang RB, Hong TM, Yang PC
Oncogene 2011 Aug 25;30(34):3682-93
Oncogene 2011 Aug 25;30(34):3682-93
Transgenic overexpression of the secreted, extracellular EGF-CUB domain-containing protein SCUBE3 induces cardiac hypertrophy in mice.
Yang HY, Cheng CF, Djoko B, Lian WS, Tu CF, Tsai MT, Chen YH, Chen CC, Cheng CJ, Yang RB
Cardiovascular research 2007 Jul 1;75(1):139-47
Cardiovascular research 2007 Jul 1;75(1):139-47
A novel secreted, cell-surface glycoprotein containing multiple epidermal growth factor-like repeats and one CUB domain is highly expressed in primary osteoblasts and bones.
Wu BT, Su YH, Tsai MT, Wasserman SM, Topper JN, Yang RB
The Journal of biological chemistry 2004 Sep 3;279(36):37485-90
The Journal of biological chemistry 2004 Sep 3;279(36):37485-90
Prostaglandin E2 modulates the functional responsiveness of human monocytes to chemokines.
Panzer U, Uguccioni M
European journal of immunology 2004 Dec;34(12):3682-9
European journal of immunology 2004 Dec;34(12):3682-9
Identification of a novel family of cell-surface proteins expressed in human vascular endothelium.
Yang RB, Ng CK, Wasserman SM, Colman SD, Shenoy S, Mehraban F, Komuves LG, Tomlinson JE, Topper JN
The Journal of biological chemistry 2002 Nov 29;277(48):46364-73
The Journal of biological chemistry 2002 Nov 29;277(48):46364-73
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of SCUBE3 in mouse kidney tissue lysate with SCUBE3 antibody Cat.-No AP55490PU-N at (A) 1 and (B) 2 ?g/mL.
