Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- BS3554 - Provider product page
- Provider
- Bioworld Technology, Inc
- Proper citation
- Bioworld Technology Cat#BS3554, RRID:AB_1661918
- Product name
- MaxiKÉÇ (K119) polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide, corresponding to amino acids 86-140 of Human MaxiKÉÇ.
- Description
- MaxiK channels are large conductance voltage and Ca 2+-activated potassium channels which are formed by tetramers of MaxiKÏ« subunits, which create pores that are used for smooth muscle tone and neuronal excitability. These MaxiKÏ« subunits have the ability to coassemble with MaxiKÉÇ subunits that are structurally related and are able to regulate the function of MaxiKÏ« subunits. KCNMB4 (potassium large conductance calcium-activated channel, subfamily M, ÉÇ member 4), also known as Slo-ÉÇ-4 or Maxi K channel subunit ÉÇ-4, is a 210 amino acid multi-pass membrane protein belonging to the KCNMB family. Predominantly expressed in brain, KCNMB4 is a regulatory subunit of the calcium activated potassium MaxiKÏ« channel. KCNMB4 contributes to MaxiKÏ« channel diversity by modulating calcium sensitivity and gating kinetics of MaxiKÏ«.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
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- Experimental details
- Western blot (WB) analysis of MaxiK¦Â (K119) pAb at 1:500 dilutionLane1:HEK293T whole cell lysateLane2:Rat brain tissue lysateLane3:PC12 whole cell lysate