PA1-24637

antibody from Invitrogen Antibodies

Targeting: GRM5 GPRC1E, mGlu5, MGLUR5, PPP1R86

Western blot (Recommended by provider)

Other assay (Supportive data in Antibodypedia)

Antibody Data

Product number

PA1-24637

Provider

Invitrogen Antibodies

Product name

mGluR5 Polyclonal Antibody

Antibody type

Polyclonal

Antigen

Synthetic peptide

Description

PA1-24637 is expected to cross react with human (100% conserved) and chicken (90% conserved) due to sequence homology.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Isotype

IgG

Vial size

50 µL

Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

References

Submitted references

Sex-Specific Anxiety and Prefrontal Cortex Glutamatergic Dysregulation Are Long-Term Consequences of Pre-and Postnatal Exposure to Hypercaloric Diet in a Rat Model.

Rivera P, Tovar R, Ramírez-López MT, Navarro JA, Vargas A, Suárez J, Fonseca FR
Nutrients 2020 Jun 19;12(6)

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Cocaine-induced behavioral sensitization decreases the expression of endocannabinoid signaling-related proteins in the mouse hippocampus.

Blanco E, Galeano P, Palomino A, Pavón FJ, Rivera P, Serrano A, Alen F, Rubio L, Vargas A, Castilla-Ortega E, Decara J, Bilbao A, de Fonseca FR, Suárez J
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2016 Mar;26(3):477-92

Other assay

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Figure 4 Effect of maternal and/or offspring exposure to a free-choice palatable (P) diet on the relative protein levels of: ( A ), GRIA1 ( B ), mGLUR5 ( C ), CB1 ( D ), CB2 ( E ), DAGLalpha ( F ), DAGLbeta ( G ), MAGL ( H ), NAPE-PLD ( I ) and FAAH ( J ) in the prefrontal cortex of male and female offspring in adulthood. Representative immunoblots ( K ). Data are expressed as the mean +- S.E.M. ( n = 4). Student's t test: * / ** / *** p < 0.05/0.01/0.001 vs. CC males or CC females; # p < 0.05 vs. CP males or CP females. MD: maternal diet effect; PD: postnatal diet effect; MDxPD: maternal and postnatal diets interaction; SxMDxPD: sex, maternal diet and postnatal diet interaction.