ADGRL2

This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors. The encoded protein participates in the regulation of exocytosis. The proprotein is thought to be further cleaved within a cysteine-rich G-protein-coupled receptor proteolysis site into two chains that are non-covalently bound at the cell membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

Description

Adhesion G protein-coupled receptor L2

Tissue specificity

Low tissue specificity

Subcell location

Plasma membrane

Predicted location

Membrane

Protein family

G-protein coupled receptors
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted membrane proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)
Transporters

Chromosome

1 (81306147 - 81992436)

Ensembl ID

ENSG00000117114  (ver. 103.38)

Orthologs

Mouse Adgrl2: ENSMUSG00000028184

UniProt

O95490

neXtProt

NX_O95490

Human splice variants
Mouse splice variants

Protein structure