Tissue expression
Cell line expression
ADGRL2
gene productKIAA0786, LEC1, LPHH1, LPHN2
This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors. The encoded protein participates in the regulation of exocytosis. The proprotein is thought to be further cleaved within a cysteine-rich G-protein-coupled receptor proteolysis site into two chains that are non-covalently bound at the cell membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
- Description
- Adhesion G protein-coupled receptor L2
- Tissue specificity
- Low tissue specificity
- Subcell location
- Plasma membrane
- Predicted location
- Membrane
- Protein family
- G-protein coupled receptors
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted membrane proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)
Transporters
- Chromosome
- 1:p31.1 (81306147 - 81992436)
- Ensembl ID
- ENSG00000117114 (ver. 103.38)
- Orthologs
- Mouse Adgrl2: ENSMUSG00000028184
- UniProt
- O95490
- neXtProt
- NX_O95490
Human splice variants
Mouse splice variants
Ensembl | UniProt | RefSeq | Entrez |
---|---|---|---|
ENSMUST00000106128 ENSMUSP00000101734 |
Q8JZZ7.135 Q8JZZ7 | Adgrl2 99633 | |
ENSMUST00000168352 ENSMUSP00000132116 |
Adgrl2 99633 | ||
ENSMUST00000195988 ENSMUSP00000143444 |
Adgrl2 99633 | ||
ENSMUST00000196526 ENSMUSP00000143788 |
Adgrl2 99633 | ||
ENSMUST00000197348 ENSMUSP00000142618 |
Adgrl2 99633 | ||
ENSMUST00000197567 ENSMUSP00000143626 |
NP_001074767.1 NP_001074767 | Adgrl2 99633 | |
ENSMUST00000197925 ENSMUSP00000143760 |
Adgrl2 99633 | ||
ENSMUST00000198139 ENSMUSP00000143511 |
Adgrl2 99633 | ||
ENSMUST00000198779 ENSMUSP00000142347 |
Adgrl2 99633 | ||
ENSMUST00000199059 ENSMUSP00000143150 |
Adgrl2 99633 | ||
ENSMUST00000199238 ENSMUSP00000142405 |
Adgrl2 99633 | ||
ENSMUST00000199750 ENSMUSP00000143320 |
Adgrl2 99633 | ||
ENSMUST00000200154 ENSMUSP00000142865 |
Adgrl2 99633 | ||
ENSMUST00000200216 ENSMUSP00000142505 |
Adgrl2 99633 | ||
ENSMUST00000200456 ENSMUSP00000142371 |
Adgrl2 99633 | ||
ENSMUST00000200543 ENSMUSP00000142336 |
Adgrl2 99633 |
* nTPM: Normalized TPM levels represent consensus gene expression calculated using two data sets. Read more
RNA data sourced from Human Protein Atlas.