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- Antigen structure
- References [17]
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- Western blot [2]
- Immunohistochemistry [2]
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- Product number
- 14192-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14192-1-AP, RRID:AB_2119643
- Product name
- HSD11B2 antibody
- Antibody type
- Polyclonal
- Description
- HSD11B2 antibody (Cat. #14192-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Mineralocorticoid promotes intestinal inflammation through receptor dependent IL17 production in ILC3s.
Cholic acid exposure during late pregnancy causes placental dysfunction and fetal growth restriction by reactive oxygen species-mediated activation of placental GCN2/eIF2α pathway.
Identification and clinical validation of key genes as the potential biomarkers in colorectal adenoma.
A gut-brain axis mediates sodium appetite via gastrointestinal peptide regulation on a medulla-hypothalamic circuit.
Maternal High-Fructose Corn Syrup Intake Impairs Corticosterone Clearance by Reducing Renal 11β-Hsd2 Activity via miR-27a-Mediated Mechanism in Rat Offspring.
Mineralocorticoid Receptor Antagonists Cause Natriuresis in the Absence of Aldosterone.
Modulation of the oral glucocorticoid system during black raspberry mediated oral cancer chemoprevention.
Effects of High-Fructose Corn Syrup Intake on Glucocorticoid Metabolism in Rats During Childhood, Adolescence and Adulthood.
Proteomics analysis reveals the effect of 1α,25(OH)(2)VD(3)-glycosides on development of early testes in piglets.
Heat stress affects fetal brain and intestinal function associated with the alterations of placental barrier in late pregnant mouse.
Response of the maternal hypothalamus to cold stress during late pregnancy in rats.
Aldosterone induced up-expression of ICAM-1 and ET-1 in pancreatic islet endothelium may associate with progression of T2D.
Chemosensory modulation of neural circuits for sodium appetite.
Placental glucocorticoid receptor and 11β-hydroxysteroid dehydrogenase-2 recruitment indicates impact of prenatal adversity upon postnatal development in mice.
Impact of prenatal cold stress on placental physiology, inflammatory response, and apoptosis in rats.
Steroidogenic enzyme profile in an androgen-secreting adrenocortical oncocytoma associated with hirsustism.
Expression of 11β-hydroxysteroid dehydrogenase type 2 is deregulated in colon carcinoma.
Zhao R, Hong L, Shi G, Ye H, Lou X, Zhou X, Yao J, Shi X, An J, Sun M
International immunopharmacology 2024 Mar 30;130:111678
International immunopharmacology 2024 Mar 30;130:111678
Cholic acid exposure during late pregnancy causes placental dysfunction and fetal growth restriction by reactive oxygen species-mediated activation of placental GCN2/eIF2α pathway.
Lin S, Ye MY, Fu QY, Pan CL, Liu YJ, Zheng LM, Hong Q, Chen YH
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Mar;37(3):e22820
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Mar;37(3):e22820
Identification and clinical validation of key genes as the potential biomarkers in colorectal adenoma.
Wang B, Zhang J, Wang X, Zhao L, Wang Y, Fan Z, Liu L, Gao W
BMC cancer 2023 Jan 11;23(1):39
BMC cancer 2023 Jan 11;23(1):39
A gut-brain axis mediates sodium appetite via gastrointestinal peptide regulation on a medulla-hypothalamic circuit.
Liu Y, Wei JA, Luo Z, Cui J, Luo Y, Mak SOK, Wang S, Zhang F, Yang Y, So KF, Shi L, Zhang L, Chow BKC
Science advances 2023 Feb 15;9(7):eadd5330
Science advances 2023 Feb 15;9(7):eadd5330
Maternal High-Fructose Corn Syrup Intake Impairs Corticosterone Clearance by Reducing Renal 11β-Hsd2 Activity via miR-27a-Mediated Mechanism in Rat Offspring.
Nouchi Y, Munetsuna E, Yamada H, Yamazaki M, Ando Y, Mizuno G, Ikeya M, Kageyama I, Wakasugi T, Teshigawara A, Hattori Y, Tsuboi Y, Ishikawa H, Suzuki K, Ohashi K
Nutrients 2023 Apr 28;15(9)
Nutrients 2023 Apr 28;15(9)
Mineralocorticoid Receptor Antagonists Cause Natriuresis in the Absence of Aldosterone.
Maeoka Y, Su XT, Wang WH, Duan XP, Sharma A, Li N, Staub O, McCormick JA, Ellison DH
Hypertension (Dallas, Tex. : 1979) 2022 Jul;79(7):1423-1434
Hypertension (Dallas, Tex. : 1979) 2022 Jul;79(7):1423-1434
Modulation of the oral glucocorticoid system during black raspberry mediated oral cancer chemoprevention.
Nedungadi D, Ryan N, Anderson K, Lamenza FF, Jordanides PP, Swingler MJ, Rakotondraibe L, Riedl KM, Iwenofu H, Oghumu S
Carcinogenesis 2022 Feb 11;43(1):28-39
Carcinogenesis 2022 Feb 11;43(1):28-39
Effects of High-Fructose Corn Syrup Intake on Glucocorticoid Metabolism in Rats During Childhood, Adolescence and Adulthood.
Nouchi Y, Munetsuna E, Yamada H, Yamazaki M, Ando Y, Mizuno G, Fujii R, Kageyama I, Wakasugi T, Sakakibara T, Teshigawara A, Ishikawa H, Shimono Y, Suzuki K, Hashimoto S, Ohashi K
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2022 Dec;130(12):814-820
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2022 Dec;130(12):814-820
Proteomics analysis reveals the effect of 1α,25(OH)(2)VD(3)-glycosides on development of early testes in piglets.
Chen H, Bühler K, Zhu Y, Nie X, Liu W
Scientific reports 2021 May 31;11(1):11341
Scientific reports 2021 May 31;11(1):11341
Heat stress affects fetal brain and intestinal function associated with the alterations of placental barrier in late pregnant mouse.
Guo H, Yang Y, Qiao Y, He J, Yao W, Zheng W
Ecotoxicology and environmental safety 2021 Dec 20;227:112916
Ecotoxicology and environmental safety 2021 Dec 20;227:112916
Response of the maternal hypothalamus to cold stress during late pregnancy in rats.
Wang D, Xu B, Wang J, Wang H, Guo J, Ji H, Li S, Wu R, Yang H, Lian S
Brain research 2019 Nov 1;1722:146354
Brain research 2019 Nov 1;1722:146354
Aldosterone induced up-expression of ICAM-1 and ET-1 in pancreatic islet endothelium may associate with progression of T2D.
Wang J, Hu H, Song J, Yan F, Qin J, Guo X, Cui C, He Q, Hou X, Liu F, Chen L
Biochemical and biophysical research communications 2019 May 14;512(4):750-757
Biochemical and biophysical research communications 2019 May 14;512(4):750-757
Chemosensory modulation of neural circuits for sodium appetite.
Lee S, Augustine V, Zhao Y, Ebisu H, Ho B, Kong D, Oka Y
Nature 2019 Apr;568(7750):93-97
Nature 2019 Apr;568(7750):93-97
Placental glucocorticoid receptor and 11β-hydroxysteroid dehydrogenase-2 recruitment indicates impact of prenatal adversity upon postnatal development in mice.
Gross M, Romi H, Gilimovich Y, Drori E, Pinhasov A
Stress (Amsterdam, Netherlands) 2018 Nov;21(6):474-483
Stress (Amsterdam, Netherlands) 2018 Nov;21(6):474-483
Impact of prenatal cold stress on placental physiology, inflammatory response, and apoptosis in rats.
Lian S, Guo J, Wang L, Li W, Wang J, Ji H, Kong F, Xu B, Li S, Yang H
Oncotarget 2017 Dec 29;8(70):115304-115314
Oncotarget 2017 Dec 29;8(70):115304-115314
Steroidogenic enzyme profile in an androgen-secreting adrenocortical oncocytoma associated with hirsustism.
Tetsi Nomigni M, Ouzounian S, Benoit A, Vadrot J, Tissier F, Renouf S, Lefebvre H, Christin-Maitre S, Louiset E
Endocrine connections 2015 Jun;4(2):117-27
Endocrine connections 2015 Jun;4(2):117-27
Expression of 11β-hydroxysteroid dehydrogenase type 2 is deregulated in colon carcinoma.
Moravec M, Svec J, Ergang P, Mandys V, Reháková L, Zádorová Z, Hajer J, Kment M, Pácha J
Histology and histopathology 2014 Apr;29(4):489-96
Histology and histopathology 2014 Apr;29(4):489-96
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with 14192-1-AP( HSD11B2 Antibody) at dilution of 1:1000
- Sample type
- cell line
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human kidney tissue were subjected to SDS PAGE followed by western blot with 14192-1-AP(HSD11B2 antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 14192-1-AP(HSD11B2 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The HSD11B2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human HSD11B2. This antibody recognizes human,mouse,rat antigen. The HSD11B2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
