Tissue expression
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Protein structure

AGTR2

Angiotensin II receptor type 2
AT2, MRX88 
The protein encoded by this gene belongs to the G-protein coupled receptor 1 family, and functions as a receptor for angiotensin II. It is an intergral membrane protein that is highly expressed in fetus and in neonates, but scantily in adult tissues, except brain, adrenal medulla, and atretic ovary. This receptor has been shown to mediate programmed cell death and this apoptotic function may play an important role in developmental biology and pathophysiology. Mutations in this gene are been associated with X-linked cognitive disability. Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and SARS-CoV-2 infection results in down-regulation of angiotensin converting enzyme-2 (ACE2) receptors, the effects of which, triggers serious inflammatory lesions in the tissues involved, primarily in the lungs. The inflammatory reaction appears to be mediated by angiotensin II derivatives, including the angiotensin AT2 receptor which has been found to be upregulated in bronchoalveolar lavage samples from Coronavirus disease 2019 (COVID19) patients. [provided by RefSeq, Jul 2020]
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263 antibodies from 35 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
35 antibodies
Invitrogen Antibodies
7 antibodies
Boster Biological Technology
3 antibodies
antibodies-online
90 antibodies
Enzo Life Sciences
4 antibodies
GeneTex
3 antibodies
R&D Systems
10 antibodies
Acris Antibodies GmbH
2 antibodies
Affinity Biosciences
1 antibody
OriGene
4 antibodies
Abnova Corporation
3 antibodies
Cusabio Biotech Co., Ltd
2 antibodies
Abgent
3 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
HUABIO Research
1 antibody
ProSci
1 antibody
St John's Laboratory
4 antibodies
Creative Biolabs
12 antibodies
RabMAbs
2 antibodies
Aviva Systems Biology
1 antibody
NSJ Bioreagents
1 antibody
MyBioSource
3 antibodies
MilliporeSigma / Merck KGaA
3 antibodies
Abbiotec
1 antibody
NovoPro Bioscience Inc.
1 antibody
Proteintech Group
1 antibody
Abbexa
2 antibodies
Leading Biology
2 antibodies
United States Biological
12 antibodies
Creative Diagnostics
2 antibodies
EMD Millipore
2 antibodies
RayBiotech, Inc.
1 antibody
Rockland Immunochemicals, Inc.
1 antibody