Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations [0]
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- Product number
- V2462 - Provider product page
- Provider
- NSJ Bioreagents
- Product name
- CCR5 Antibody
- Antibody type
- Monoclonal
- Antigen
- Human native protein was used as the immunogen for the CCR5 antibody.
- Description
- Protein G purified antibody
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antibody clone number
- 12D1
- Vial size
- 20 µg, 100 µg (with sodium azide), 100 µg (without sodium azide), 7 ml (prediluted for IHC use, if applicable)
- Storage
- Store the CCR5 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Submitted references Monoclonal antibody-assisted stimulation of adenosine A2A receptors induces simultaneous downregulation of CXCR4 and CCR5 on CD4+ T-cells.
Human herpesvirus 6A decreases the susceptibility of macrophages to R5 variants of human immunodeficiency virus 1: possible role of RANTES and IL-8.
Molecular modeling and site-directed mutagenesis of CCR5 reveal residues critical for chemokine binding and signal transduction.
The anti-HIV pseudopeptide HB-19 forms a complex with the cell-surface-expressed nucleolin independent of heparan sulfate proteoglycans.
CCR5 HIV-1 coreceptor activity. Role of cooperativity between residues in N-terminal extracellular and intracellular domains.
The V3 loop-mimicking pseudopeptide 5[Kpsi(CH2N)PR]-TASP inhibits HIV infection in primary macrophage cultures.
CXCR4 sequences involved in coreceptor determination of human immunodeficiency virus type-1 tropism. Unmasking of activity with M-tropic Env glycoproteins.
By Y, Durand-Gorde JM, Condo J, Lejeune PJ, Fenouillet E, Guieu R, Ruf J
Human immunology 2010 Nov;71(11):1073-6
Human immunology 2010 Nov;71(11):1073-6
Human herpesvirus 6A decreases the susceptibility of macrophages to R5 variants of human immunodeficiency virus 1: possible role of RANTES and IL-8.
Csoma E, Deli T, Kónya J, Csernoch L, Beck Z, Gergely L
Virus research 2006 Nov;121(2):161-8
Virus research 2006 Nov;121(2):161-8
Molecular modeling and site-directed mutagenesis of CCR5 reveal residues critical for chemokine binding and signal transduction.
Zhou N, Luo Z, Hall JW, Luo J, Han X, Huang Z
European journal of immunology 2000 Jan;30(1):164-73
European journal of immunology 2000 Jan;30(1):164-73
The anti-HIV pseudopeptide HB-19 forms a complex with the cell-surface-expressed nucleolin independent of heparan sulfate proteoglycans.
Nisole S, Krust B, Callebaut C, Guichard G, Muller S, Briand JP, Hovanessian AG
The Journal of biological chemistry 1999 Sep 24;274(39):27875-84
The Journal of biological chemistry 1999 Sep 24;274(39):27875-84
CCR5 HIV-1 coreceptor activity. Role of cooperativity between residues in N-terminal extracellular and intracellular domains.
Wang Z, Lee B, Murray JL, Bonneau F, Sun Y, Schweickart V, Zhang T, Peiper SC
The Journal of biological chemistry 1999 Oct 1;274(40):28413-9
The Journal of biological chemistry 1999 Oct 1;274(40):28413-9
The V3 loop-mimicking pseudopeptide 5[Kpsi(CH2N)PR]-TASP inhibits HIV infection in primary macrophage cultures.
Seddiki N, Nisole S, Krust B, Callebaut C, Guichard G, Muller S, Briand JP, Hovanessian AG
AIDS research and human retroviruses 1999 Mar 1;15(4):381-90
AIDS research and human retroviruses 1999 Mar 1;15(4):381-90
CXCR4 sequences involved in coreceptor determination of human immunodeficiency virus type-1 tropism. Unmasking of activity with M-tropic Env glycoproteins.
Wang ZX, Berson JF, Zhang TY, Cen YH, Sun Y, Sharron M, Lu ZH, Peiper SC
The Journal of biological chemistry 1998 Jun 12;273(24):15007-15
The Journal of biological chemistry 1998 Jun 12;273(24):15007-15
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