Tissue expression
Cell line expression

CCR5

gene product
CC-CKR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22 
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. An allelic polymorphism in this gene results in both functional and non-functional alleles; the reference genome represents the functional allele. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2015]
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1881 antibodies from 48 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
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1 antibody
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4 antibodies
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Wuhan Fine Biotech Co., Ltd.
1 antibody
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20 antibodies
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Creative Diagnostics
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2 antibodies
RayBiotech, Inc.
3 antibodies
RabMAbs
2 antibodies
Signalway Antibody LLC
1 antibody
Miltenyi Biotec
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3 antibodies
Leading Biology
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Abbexa
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Abbiotec
1 antibody
United States Biological
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Exalpha Biologicals, Inc.
2 antibodies
EMD Millipore
1 antibody