Tissue expression
Cell line expression
Protein structure

CCR5

C-C motif chemokine receptor 5
CC-CKR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22 
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. An allelic polymorphism in this gene results in both functional and non-functional alleles; the reference genome represents the functional allele. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2015]
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AntibodyRefsTypeWBELICCIPIHCFC
R&D Systems
70 antibodies
antibodies-online
613 antibodies
Proteintech Group
2 antibodies
Invitrogen Antibodies
44 antibodies
GeneTex
21 antibodies
OriGene
28 antibodies
Novus Biologicals
173 antibodies
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9 antibodies
Biorbyt
162 antibodies
Antibodies.com
3 antibodies
Acris Antibodies GmbH
24 antibodies
St John's Laboratory
17 antibodies
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3 antibodies
BioLegend
60 antibodies
NSJ Bioreagents
7 antibodies
Affinity Biosciences
3 antibodies
Abnova Corporation
11 antibodies
Cusabio Biotech Co., Ltd
18 antibodies
NovoPro Bioscience Inc.
4 antibodies
Abbkine Scientific Co.Ltd.
6 antibodies
Aladdin Scientific Corporation
1 antibody
FineTest Biotech
1 antibody
Aviva Systems Biology
20 antibodies
MilliporeSigma / Merck KGaA
7 antibodies
ProSci
4 antibodies
FabGennix
6 antibodies
Abgent
4 antibodies
Aldevron
1 antibody
Absolute Antibody
25 antibodies
Arigo
5 antibodies
Creative Diagnostics
13 antibodies
MyBioSource
17 antibodies
Bioworld Technology, Inc
3 antibodies
eBioscience, An Affymetrix Company
8 antibodies
ABEOMICS Inc.
2 antibodies
Creative Biolabs
230 antibodies
RayBiotech, Inc.
3 antibodies
RabMAbs
2 antibodies
Signalway Antibody LLC
1 antibody
Miltenyi Biotec
8 antibodies
Abiocode, Inc.
3 antibodies
Leading Biology
3 antibodies
Abbexa
28 antibodies
Abbiotec
1 antibody
DIMA
1 antibody
QED Bioscience
1 antibody
United States Biological
78 antibodies
EMD Millipore
1 antibody