313710

antibody from BioLegend

Targeting: CCR5 CC-CKR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22

Antibody data

Submit

Validation data

Product number: 313710 - Provider product page
Provider: BioLegend
Proper citation: BioLegend Cat#313710, RRID:AB_528758
Product name: Alexa Fluor® 488 anti-human CD195 (CCR5) [HEK/1/85a]
Antibody type: Monoclonal
Antigen: CHO cells transfected with human CCR5
Description: CD195, also known as CCR5, is a 45 kD G protein-coupled seven transmembrane CC-chemokine receptor. It binds to MIP-1α, MIP-1β, and RANTES and is expressed on a subset of T cells and monocytes. CD195 mediates an intracellular signal thought to induce cell differentiation and proliferation. CCR5 has also been shown to act as a co-receptor for R5 HIV-1 cell entry; modification of CCR5 by sulfation contributes to the efficiency of HIV-1 entry. Recent studies have shown CCR5 to play a role in a variety of other human diseases, ranging from infectious and inflammatory diseases to cancer.
Reactivity: Human
Host: Rat
Conjugate: Green dye
Isotype: IgG
Vial size: 100 tests
Storage: The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

CCR5 protein structure - 313710 shown in red.