313716

antibody from BioLegend
Targeting: CCR5 CC-CKR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22
Provider product page for 313716

Antibody data

Product number
313716 - Provider product page
Provider
BioLegend
Product name
PerCP/Cy5.5 anti-human CD195 (CCR5)
Antibody type
Monoclonal
Antigen
CHO cells transfected with human CCR5
Description
CD195, also known as CCR5, is a 45 kD G protein-coupled seven transmembrane CC-chemokine receptor. It binds to MIP-1α, MIP-1β, and RANTES and is expressed on a subset of T cells and monocytes. CD195 mediates an intracellular signal thought to induce cell differentiation and proliferation. CCR5 has also been shown to act as a co-receptor for R5 HIV-1 cell entry; modification of CCR5 by sulfation contributes to the efficiency of HIV-1 entry. Recent studies have shown CCR5 to play a role in a variety of other human diseases, ranging from infectious and inflammatory diseases to cancer.
Reactivity
Human
Host
Rat
Conjugate
Far-Red dye
Isotype
IgG
Vial size
100 tests
Storage
The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
CCR5 protein structure - 313716 shown in red.