321702

antibody from BioLegend
Targeting: CCR5 CC-CKR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22
Provider product page for 321702
Western blot
ELISA
Immunoprecipitation

Antibody data

Product number
321702 - Provider product page
Provider
BioLegend
Product name
Purified anti-human CD195 (CCR5) (cytoplasmic domain)
Antibody type
Monoclonal
Antigen
Peptide (CEAPERASSVYTRSTGEQISVGL) of CCR5
Description
CD195, also known as CCR5, is a 45 kD G protein-coupled seven transmembrane CC-chemokine receptor. It binds to MIP-1α, MIP-1β, and RANTES and is expressed on a subset of T cells and monocytes. CD195 mediates an intracellular signal thought to induce cell differentiation and proliferation. CCR5 has also been shown to act as a co-receptor for R5 HIV-1 cell entry; modification of CCR5 by sulfation contributes to the efficiency of HIV-1 entry. The R-C10 monoclonal antibody binds to nonphosphorylated serine 337 corresponding to 22 c-terminal amino acid residues of human CCR5 and is useful for flow cytometric analysis, immunoblotting, and ELISA assay of CCR5 expression.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Isotype
IgG
Vial size
100 µg
Concentration
0.5 mg/ml
Storage
The antibody solution should be stored undiluted at 4°C.
CCR5 protein structure - 321702 shown in red.