Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
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- Product number
- 55377-1-AP - Provider product page

- Provider
- Proteintech Group
- Product name
- SETD2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated SETD2 antibody (Cat. #55377-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references H3K36me3-Guided m(6)A Modification of Oncogenic L1CAM-AS1 Drives Macrophage Polarization and Immunotherapy Resistance in Hepatocellular Carcinoma.
Polydatin Alleviated Ischemia-Reperfusion Induced Kidney Injury by Inhibiting SETD2-Mediated Ferroptosis.
SETD2 drives METTL14-mediated m(6)A to suppress Piezo1 Attenuation and activate TGM2 to promote pulmonary hypertension.
Structure and Function of RhoBTB1 Required for Substrate Specificity and Cullin-3 Ubiquitination.
Knockdown of SETD2 promotes erastin-induced ferroptosis in ccRCC.
A novel FBW7/NFAT1 axis regulates cancer immunity in sunitinib-resistant renal cancer by inducing PD-L1 expression.
Proteomic analysis of the OGT interactome: novel links to epithelial-mesenchymal transition and metastasis of cervical cancer.
PHD finger protein 1 (PHF1) is a novel reader for histone H4R3 symmetric dimethylation and coordinates with PRMT5-WDR77/CRL4B complex to promote tumorigenesis.
Wang T, Han L, Huo Y, Zhang L, Huang Y, Zhang N, Yang M
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(33):e14909
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(33):e14909
Polydatin Alleviated Ischemia-Reperfusion Induced Kidney Injury by Inhibiting SETD2-Mediated Ferroptosis.
He M, Tang S, Wang L, Hu X, Yao X, Wu H
Phytotherapy research : PTR 2025 Nov;39(11):5391-5408
Phytotherapy research : PTR 2025 Nov;39(11):5391-5408
SETD2 drives METTL14-mediated m(6)A to suppress Piezo1 Attenuation and activate TGM2 to promote pulmonary hypertension.
Zhao SS, Yuan C, Liu JL, Wu QC, Zhou XL
Cellular and molecular life sciences : CMLS 2025 Aug 8;82(1):302
Cellular and molecular life sciences : CMLS 2025 Aug 8;82(1):302
Structure and Function of RhoBTB1 Required for Substrate Specificity and Cullin-3 Ubiquitination.
Kumar G, Fang S, Golosova D, Lu KT, Brozoski DT, Vazirabad I, Sigmund CD
Function (Oxford, England) 2023;4(5):zqad034
Function (Oxford, England) 2023;4(5):zqad034
Knockdown of SETD2 promotes erastin-induced ferroptosis in ccRCC.
Xue W, Jian W, Meng Y, Wang T, Cai L, Yu Y, Yu Y, Xia Z, Zhang C
Cell death & disease 2023 Aug 21;14(8):539
Cell death & disease 2023 Aug 21;14(8):539
A novel FBW7/NFAT1 axis regulates cancer immunity in sunitinib-resistant renal cancer by inducing PD-L1 expression.
Liu W, Ren D, Xiong W, Jin X, Zhu L
Journal of experimental & clinical cancer research : CR 2022 Jan 26;41(1):38
Journal of experimental & clinical cancer research : CR 2022 Jan 26;41(1):38
Proteomic analysis of the OGT interactome: novel links to epithelial-mesenchymal transition and metastasis of cervical cancer.
Gao J, Yang Y, Qiu R, Zhang K, Teng X, Liu R, Wang Y
Carcinogenesis 2018 Oct 8;39(10):1222-1234
Carcinogenesis 2018 Oct 8;39(10):1222-1234
PHD finger protein 1 (PHF1) is a novel reader for histone H4R3 symmetric dimethylation and coordinates with PRMT5-WDR77/CRL4B complex to promote tumorigenesis.
Liu R, Gao J, Yang Y, Qiu R, Zheng Y, Huang W, Zeng Y, Hou Y, Wang S, Leng S, Feng D, Yu W, Sun G, Shi H, Teng X, Wang Y
Nucleic acids research 2018 Jul 27;46(13):6608-6626
Nucleic acids research 2018 Jul 27;46(13):6608-6626
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The SETD2 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human SETD2. This antibody recognizes human antigen. The SETD2 antibody has been validated for the following applications: ELISA, WB, IF analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunofluorescent analysis of HepG2 cells using 55377-1-AP( SETD2 Antibody) at dilution of 1:50 and Rhodamine-Goat anti-Rabbit IgG
- Sample type
- cell line