SETD2

gene product
FLJ23184, HIF-1, HYPB, KIAA1732, KMT3A
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug 2008]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI
343 antibodies from 34 providers.

Antibody properties

General

Applications

or Cancel
Antibody
Bioworld Technology, Inc
1 antibody
Proteintech Group
1 antibody
Novus Biologicals
25 antibodies
Atlas Antibodies
2 antibodies
Invitrogen Antibodies
8 antibodies
Wuhan Fine Biotech Co., Ltd.
1 antibody
antibodies-online
92 antibodies
Biorbyt
17 antibodies
Affinity Biosciences
3 antibodies
LifeSpan BioSciences, Inc.
51 antibodies
Cell Signaling Technology, Inc
4 antibodies
NovoPro Bioscience Inc.
1 antibody
OriGene
15 antibodies
GeneTex
5 antibodies
Abnova Corporation
4 antibodies
Aviva Systems Biology
2 antibodies
Cusabio Biotech Co., Ltd
2 antibodies
ProSci
2 antibodies
Antibodies.com
1 antibody
Boster Biological Technology
1 antibody
United States Biological
62 antibodies
MyBioSource
6 antibodies
Everest Biotech
2 antibodies
Acris Antibodies GmbH
1 antibody
NSJ Bioreagents
1 antibody
Arigo
2 antibodies
Abgent
1 antibody
St John's Laboratory
4 antibodies
Abiocode, Inc.
1 antibody
Absolute Antibody
5 antibodies
Abbexa
4 antibodies
MilliporeSigma / Merck KGaA
3 antibodies
Creative Biolabs
11 antibodies
Creative Diagnostics
2 antibodies