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antibody from Invitrogen Antibodies
Targeting: SETD2
FLJ23184, HIF-1, HYPB, KIAA1732, KMT3A
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Immunocytochemistry [1]
- Immunohistochemistry [4]
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- Product number
- PA5-83615 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- SETD2 Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full-length protein
- Description
- Immunogen sequence: NLGMTSPLPY DSLGYNAPHH PFAGYPPGYP MQAYVDPSNP NAGKVLLPTP SMDPVCSPAP YDHAQPLVGH STEPLSAPPP VPVVPHVAAP VEVSSSQYVA
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 µL
- Concentration
- 0.2 mg/mL
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Submitted references The Huntingtin-interacting protein SETD2/HYPB is an actin lysine methyltransferase.
Seervai RNH, Jangid RK, Karki M, Tripathi DN, Jung SY, Kearns SE, Verhey KJ, Cianfrocco MA, Millis BA, Tyska MJ, Mason FM, Rathmell WK, Park IY, Dere R, Walker CL
Science advances 2020 Oct;6(40)
Science advances 2020 Oct;6(40)
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of SETD2 in A-431 cells using a SETD2 polyclonal antibody (Product # PA5-83615). The analysis shows localization to nuclear speckles & cytosol.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of SETD2 in human endometrium using SETD2 Polyclonal Antibody (Product # PA5-83615) shows strong nuclear positivity in glandular and stromal cells.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of SETD2 in human testis using SETD2 Polyclonal Antibody (Product # PA5-83615) shows moderate nuclear positivity in cells in seminiferous ducts.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of SETD2 in human cerebellum using SETD2 Polyclonal Antibody (Product # PA5-83615) shows moderate nuclear positivity in Purkinje cells as well as in cells in molecular layer.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of SETD2 in human small intestine using SETD2 Polyclonal Antibody (Product # PA5-83615) shows strong nuclear positivity in glandular cells.
