abx002294

antibody from Abbexa

Targeting: SETD2 FLJ23184, HIF-1, HYPB, KIAA1732, KMT3A

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Antibody Data

Product number

abx002294

Provider

Abbexa

Product name

SET Domain Containing Protein 2 (SETD2) Antibody

Antibody type

Polyclonal

Description

SETD2 Antibody is a Rabbit Polyclonal antibody against SETD2. Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

1.23 mg/ml

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.