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Cell line expression
Protein structure
SIPA1
Signal-induced proliferation-associated 1SPA1
The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| LSBio |  LS-B10609 |
Polyclonal |
WB
EL
IHC
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| antibodies-online | ABIN1450109 |
4 references | Polyclonal |
WB
EL
ICC
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| GeneTex | GTX31846 |
Polyclonal |
WB
EL
ICC
IHC
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| Proteintech Group | 26793-1-AP |
1 references | Polyclonal |
WB
EL
ICC
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| Abnova Corporation | PAB11325 |
3 references | Polyclonal |
WB
IHC
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