Tissue expression
Cell line expression

MCFD2

gene product
F5F8D, LMAN1IP, SDNSF 
This gene encodes a soluble luminal protein with two calmodulin-like EF-hand motifs at its C-terminus. This protein forms a complex with LMAN1 (lectin mannose binding protein 1; also known as ERGIC-53) that facilitates the transport of coagulation factors V (FV) and VIII (FVIII) from the endoplasmic reticulum to the Golgi apparatus via an endoplasmic reticulum Golgi intermediate compartment (ERGIC). Mutations in this gene cause combined deficiency of FV and FVIII (F5F8D); a rare autosomal recessive bleeding disorder characterized by mild to moderate bleeding and coordinate reduction in plasma FV and FVIII levels. This protein has also been shown to maintain stem cell potential in adult central nervous system and is a marker for testicular germ cell tumors. The 3' UTR of this gene contains a transposon-like human repeat element named 'THE 1'. A processed RNA pseudogene of this gene is on chromosome 6p22.1. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Apr 2016]
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183 antibodies from 28 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
9 antibodies
LifeSpan BioSciences, Inc.
30 antibodies
Abnova Corporation
5 antibodies
antibodies-online
53 antibodies
R&D Systems
6 antibodies
NovoPro Bioscience Inc.
2 antibodies
Proteintech Group
1 antibody
Acris Antibodies GmbH
4 antibodies
RabMAbs
1 antibody
Biorbyt
13 antibodies
Invitrogen Antibodies
6 antibodies
Abgent
1 antibody
Atlas Antibodies
1 antibody
Aviva Systems Biology
1 antibody
Bioworld Technology, Inc
1 antibody
NSJ Bioreagents
1 antibody
Creative Diagnostics
2 antibodies
Bioss
1 antibody
Boster Biological Technology
1 antibody
GeneTex
1 antibody
RayBiotech, Inc.
1 antibody
Creative Biolabs
9 antibodies
MyBioSource
2 antibodies
MilliporeSigma / Merck KGaA
2 antibodies
EMD Millipore
1 antibody
United States Biological
25 antibodies
Abbexa
2 antibodies
Leading Biology
1 antibody