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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [2]
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- Product number
- ABIN2145231 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-5'-Nucleotidase, Ecto (CD73) (NT5E) antibody
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- Purified
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 4AAD2
- Vial size
- 500 μg
- Storage
- 4°C
Submitted references Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression.
T regulatory and primed uncommitted CD4 T cells express CD73, which suppresses effector CD4 T cells by converting 5'-adenosine monophosphate to adenosine.
Deaglio S, Dwyer KM, Gao W, Friedman D, Usheva A, Erat A, Chen JF, Enjyoji K, Linden J, Oukka M, Kuchroo VK, Strom TB, Robson SC
The Journal of experimental medicine 2007 Jun 11;204(6):1257-65
The Journal of experimental medicine 2007 Jun 11;204(6):1257-65
T regulatory and primed uncommitted CD4 T cells express CD73, which suppresses effector CD4 T cells by converting 5'-adenosine monophosphate to adenosine.
Kobie JJ, Shah PR, Yang L, Rebhahn JA, Fowell DJ, Mosmann TR
Journal of immunology (Baltimore, Md. : 1950) 2006 Nov 15;177(10):6780-6
Journal of immunology (Baltimore, Md. : 1950) 2006 Nov 15;177(10):6780-6
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