Tissue expression
Cell line expression
Protein structure
NPTX2
Neuronal pentraxin 2This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD. [provided by RefSeq, Feb 2009]
Top validated antibodies |
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| Proteintech Group | 17 references | Polyclonal |
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| LSBio | Polyclonal |
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| Invitrogen Antibodies | Polyclonal |
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| GeneTex | Polyclonal |
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| Novus Biologicals | Polyclonal |
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