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Protein structure
LGI1
Leucine rich glioma inactivated 1EPITEMPIN, EPT, ETL1, IB1099
This gene encodes a member of the secreted leucine-rich repeat (LRR) superfamily and shares homology with members of the SLIT protein family. The encoded protein may regulate the activity of voltage-gated potassium channels and may be involved in neuronal growth regulation and cell survival. This gene is rearranged as a result of translocations in glioblastoma cell lines, and it is frequently down-regulated or rearranged in malignant gliomas. Mutations in this gene result in autosomal dominant lateral temporal epilepsy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
Top validated antibodies |
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| LSBio |  LS-C53265 |
Polyclonal |
WB
EL
ICC
IHC
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| Novus Biologicals | NBP1-77320 |
Polyclonal |
WB
EL
ICC
IHC
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| Boster Biological Technology | A00850 |
Polyclonal |
WB
EL
ICC
IHC
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| antibodies-online | ABIN2491179 |
Polyclonal |
WB
EL
IHC
FC
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| Abnova Corporation | PAB13341 |
3 references | Polyclonal |
WB
IHC
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