ABIN1673175

antibody from antibodies-online

Targeting: CYP11A1 CYP11A, P450SCC

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN1673175

Provider

antibodies-online

Product name

anti-Cytochrome P450, Family 11, Subfamily A, Polypeptide 1 (CYP11A1) (C-Term) antibody

Antibody type

Polyclonal

Antigen

A synthetic peptide corresponding to a sequence at the C-terminal of human CYP11A1.Immunogen affinity purified.

Reactivity

Human

Host

Rabbit

Epitope

C-Term

Isotype

IgG

Vial size

100 μg

Storage

At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Homozygous mutation of P450 side-chain cleavage enzyme gene (CYP11A1) in 46, XY patient with adrenal insufficiency, complete sex reversal, and agenesis of corpus callosum.

al Kandari H, Katsumata N, Alexander S, Rasoul MA
The Journal of clinical endocrinology and metabolism 2006 Aug;91(8):2821-6

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A pathway for the metabolism of vitamin D3: unique hydroxylated metabolites formed during catalysis with cytochrome P450scc (CYP11A1).

Guryev O, Carvalho RA, Usanov S, Gilep A, Estabrook RW
Proceedings of the National Academy of Sciences of the United States of America 2003 Dec 9;100(25):14754-9

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Human cholesterol side-chain cleavage enzyme, P450scc: cDNA cloning, assignment of the gene to chromosome 15, and expression in the placenta.

Chung BC, Matteson KJ, Voutilainen R, Mohandas TK, Miller WL
Proceedings of the National Academy of Sciences of the United States of America 1986 Dec;83(23):8962-6