Tissue expression
Cell line expression
Protein structure
CYP11A1
Cytochrome P450 family 11 subfamily A member 1CYP11A, P450SCC
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide. [provided by RefSeq, Jul 2008]
Top validated antibodies |
|||||
Proteintech Group | 13363-1-AP | 46 references | Polyclonal |
WB
EL
IHC
|
|
antibodies-online | ABIN701530 | 4 references | Polyclonal |
WB
ICC
IHC
|
|
Bioss | bs-3608R | 4 references | Polyclonal |
WB
ICC
IHC
|
|
Novus Biologicals | NBP1-85368 | 1 references | Polyclonal |
WB
ICC
IHC
|
|
Biorbyt | orb156513 | Polyclonal |
WB
EL
ICC
IHC
FC
|
All Antibodies
Filters
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider