Antibody data
- Antibody Data
- Antigen structure
- References [49]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
Reference
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- Product number
- 15310-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15310-1-AP, RRID:AB_2224185
- Product name
- ALDH2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ALDH2 antibody (Cat. #15310-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The aldehyde dehydrogenase 2 rs671 variant enhances amyloid β pathology.
Effects of Hovenia dulcis fruit and peduncle extract on alcohol metabolism.
Mitochondrial aldehyde dehydrogenase-2 coordinates the hydrogen sulfide - AMPK axis to attenuate high glucose-induced pancreatic β-cell dysfunction by glutathione antioxidant system.
ALDH2 deficiency exacerbates MCD-diet induced MASLD by modulating bile acid metabolism.
WDR23 mediates NRF2 proteostasis and cytoprotective capacity in the hippocampus.
DNMT1 mediates the disturbed flow-induced endothelial to mesenchymal transition through disrupting β-alanine and carnosine homeostasis.
Hepatitis B virus X protein induces ALDH2 ubiquitin-dependent degradation to enhance alcoholic steatohepatitis.
WDR23 mediates NRF2 proteostasis and cytoprotective capacity in the hippocampus.
The Binding of HSPA8 and Mitochondrial ALDH2 Mediates Oxygen-Glucose Deprivation-Induced Fibroblast Senescence.
p53 protects against alcoholic fatty liver disease via ALDH2 inhibition.
The Effects of Alda-1 Treatment on Renal and Intestinal Injuries After Cardiopulmonary Resuscitation in Pigs.
SIRT3 inhibitor 3-TYP exacerbates thioacetamide-induced hepatic injury in mice.
Impact and potential mechanism of effects of chronic moderate alcohol consumption on cardiac function in aldehyde dehydrogenase 2 gene heterozygous mice.
Aldh2 is a lineage-specific metabolic gatekeeper in melanocyte stem cells.
Metabolomics of oxidative stress: Nrf2 independent depletion of NAD or increases of sugar alcohols.
Baicalin ameliorates alcohol-induced hepatic steatosis by suppressing SREBP1c elicited PNPLA3 competitive binding to ATGL.
Aldehyde dehydrogenase 2 deficiency promotes skeletal muscle atrophy in aged mice.
Lactoferrin Prevents Chronic Alcoholic Injury by Regulating Redox Balance and Lipid Metabolism in Female C57BL/6J Mice.
Effect of different types of muscle activity on the gene and protein expression of ALDH family members in C57BL/6J mouse skeletal muscle.
The Anti-Adiposity Mechanisms of Ampelopsin and Vine Tea Extract in High Fat Diet and Alcohol-Induced Fatty Liver Mouse Models.
Alda-1, an Activator of ALDH2, Improves Postresuscitation Cardiac and Neurological Outcomes by Inhibiting Pyroptosis in Swine.
Aldehyde dehydrogenase 2 and PARP1 interaction modulates hepatic HDL biogenesis by LXRα-mediated ABCA1 expression.
Aldehyde Dehydrogenase 2 Protects Against Lipopolysaccharide-Induced Myocardial Injury by Suppressing Mitophagy.
ALDH2 is a prognostic biomarker and related with immune infiltrates in HCC.
Daily Dose of Bovine Lactoferrin Prevents Ethanol-Induced Liver Injury and Death in Male Mice by Regulating Hepatic Alcohol Metabolism and Modulating Gut Microbiota.
Transcriptional Silencing of ALDH2 Confers a Dependency on Fanconi Anemia Proteins in Acute Myeloid Leukemia.
Trehalose activates hepatic transcription factor EB (TFEB) but fails to ameliorate alcohol-impaired TFEB and liver injury in mice.
Low-Dose Pesticides Alter Primary Human Bone Marrow Mesenchymal Stem/Stromal Cells through ALDH2 Inhibition.
Aldehyde Dehydrogenase 2 Mediates Alcohol-Induced Colorectal Cancer Immune Escape through Stabilizing PD-L1 Expression.
Acetaldehyde Dehydrogenase 2 regulates HMG-CoA reductase stability and cholesterol synthesis in the liver.
Analysis of disease model iPSCs derived from patients with a novel Fanconi anemia-like IBMFS ADH5/ALDH2 deficiency.
Pretreatment with the ALDH2 activator Alda‑1 protects rat livers from ischemia/reperfusion injury by inducing autophagy.
Alda-1, an activator of ALDH2, ameliorates Achilles tendinopathy in cellular and mouse models.
Combination of podophyllotoxin and rutin modulate radiation-induced alterations of jejunal proteome in mice.
Two Aldehyde Clearance Systems Are Essential to Prevent Lethal Formaldehyde Accumulation in Mice and Humans.
Aldehyde dehydrogenase 2 protects against sympathetic excitation-induced cardiac fibrosis.
Acetaldehyde dehydrogenase 2 deficiency increases mitochondrial reactive oxygen species emission and induces mitochondrial protease Omi/HtrA2 in skeletal muscle.
Acetaldehyde dehydrogenase 2 interactions with LDLR and AMPK regulate foam cell formation.
Alda-1 Ameliorates Liver Ischemia-Reperfusion Injury by Activating Aldehyde Dehydrogenase 2 and Enhancing Autophagy in Mice.
A comparison of CRISPR/Cas9 and siRNA-mediated ALDH2 gene silencing in human cell lines.
Limitations of lymphoblastoid cell lines for functional analysis of SNPs.
Loss of NAD-Dependent Protein Deacetylase Sirtuin-2 Alters Mitochondrial Protein Acetylation and Dysregulates Mitophagy.
Alcohol Dehydrogenase 5 Is a Source of Formate for De Novo Purine Biosynthesis in HepG2 Cells.
Liver-Specific Deletion of Phosphatase and Tensin Homolog Deleted on Chromosome 10 Significantly Ameliorates Chronic EtOH-Induced Increases in Hepatocellular Damage.
Activation of peroxisome proliferator-activated receptor α ameliorates perfluorododecanoic acid-induced production of reactive oxygen species in rat liver.
Aldehyde dehydrogenase 2 inhibits inflammatory response and regulates atherosclerotic plaque.
Quantitative proteomic analysis reveals that anti-cancer effects of selenium-binding protein 1 in vivo are associated with metabolic pathways.
Protective role of ALDH2 against acetaldehyde-derived DNA damage in oesophageal squamous epithelium.
Maternal aldehyde elimination during pregnancy preserves the fetal genome.
Wang X, Wang J, Chen Y, Qian X, Luo S, Wang X, Ma C, Ge W
Nature communications 2024 Mar 22;15(1):2594
Nature communications 2024 Mar 22;15(1):2594
Effects of Hovenia dulcis fruit and peduncle extract on alcohol metabolism.
Niiya M, Shimato Y, Ohno T, Makino T
Journal of ethnopharmacology 2024 Mar 1;321:117541
Journal of ethnopharmacology 2024 Mar 1;321:117541
Mitochondrial aldehyde dehydrogenase-2 coordinates the hydrogen sulfide - AMPK axis to attenuate high glucose-induced pancreatic β-cell dysfunction by glutathione antioxidant system.
Karunakaran U, Elumalai S, Chung SM, Maedler K, Won KC, Moon JS
Redox biology 2024 Feb;69:102994
Redox biology 2024 Feb;69:102994
ALDH2 deficiency exacerbates MCD-diet induced MASLD by modulating bile acid metabolism.
Luo J, Lu Z, Zhong Z, Pi M, Xiong Y, Li L, Chen T, Chen Y, Wang CY, Liu Z, Ye Q
Free radical biology & medicine 2024 Feb 20;212:34-48
Free radical biology & medicine 2024 Feb 20;212:34-48
WDR23 mediates NRF2 proteostasis and cytoprotective capacity in the hippocampus.
Liu J, Duangjan C, Irwin RW, Curran SP
Mechanisms of ageing and development 2024 Apr;218:111914
Mechanisms of ageing and development 2024 Apr;218:111914
DNMT1 mediates the disturbed flow-induced endothelial to mesenchymal transition through disrupting β-alanine and carnosine homeostasis.
Zhao J, Zhao C, Yang F, Jiang Z, Zhu J, Yao W, Pang W, Zhou J
Theranostics 2023;13(13):4392-4411
Theranostics 2023;13(13):4392-4411
Hepatitis B virus X protein induces ALDH2 ubiquitin-dependent degradation to enhance alcoholic steatohepatitis.
Zhou H, Wan S, Luo Y, Liu H, Jiang J, Guo Y, Xiao J, Wu B
Gastroenterology report 2023;11:goad006
Gastroenterology report 2023;11:goad006
WDR23 mediates NRF2 proteostasis and cytoprotective capacity in the hippocampus.
Liu J, Duangjan C, Irwin RW, Curran SP
bioRxiv : the preprint server for biology 2023 Oct 11;
bioRxiv : the preprint server for biology 2023 Oct 11;
The Binding of HSPA8 and Mitochondrial ALDH2 Mediates Oxygen-Glucose Deprivation-Induced Fibroblast Senescence.
Hui W, Song T, Yu L, Chen X
Antioxidants (Basel, Switzerland) 2023 Dec 25;13(1)
Antioxidants (Basel, Switzerland) 2023 Dec 25;13(1)
p53 protects against alcoholic fatty liver disease via ALDH2 inhibition.
Yao P, Zhang Z, Liu H, Jiang P, Li W, Du W
The EMBO journal 2023 Apr 17;42(8):e112304
The EMBO journal 2023 Apr 17;42(8):e112304
The Effects of Alda-1 Treatment on Renal and Intestinal Injuries After Cardiopulmonary Resuscitation in Pigs.
Yu Q, Gao J, Shao X, Lu W, Chen L, Jin L
Frontiers in medicine 2022;9:892472
Frontiers in medicine 2022;9:892472
SIRT3 inhibitor 3-TYP exacerbates thioacetamide-induced hepatic injury in mice.
Shi C, Jiao F, Wang Y, Chen Q, Wang L, Gong Z
Frontiers in physiology 2022;13:915193
Frontiers in physiology 2022;13:915193
Impact and potential mechanism of effects of chronic moderate alcohol consumption on cardiac function in aldehyde dehydrogenase 2 gene heterozygous mice.
Hu Q, Chen H, Shen C, Zhang B, Weng X, Sun X, Liu J, Dong Z, Hu K, Ge J, Sun A
Alcoholism, clinical and experimental research 2022 May;46(5):707-723
Alcoholism, clinical and experimental research 2022 May;46(5):707-723
Aldh2 is a lineage-specific metabolic gatekeeper in melanocyte stem cells.
Brunsdon H, Brombin A, Peterson S, Postlethwait JH, Patton EE
Development (Cambridge, England) 2022 May 15;149(10)
Development (Cambridge, England) 2022 May 15;149(10)
Metabolomics of oxidative stress: Nrf2 independent depletion of NAD or increases of sugar alcohols.
Zhu C, Gu H, Jin Y, Wurm D, Freidhof B, Lu Y, Chen QM
Toxicology and applied pharmacology 2022 May 1;442:115949
Toxicology and applied pharmacology 2022 May 1;442:115949
Baicalin ameliorates alcohol-induced hepatic steatosis by suppressing SREBP1c elicited PNPLA3 competitive binding to ATGL.
Li P, Chen Y, Ke X, Zhang R, Zuo L, Wang M, Chen Z, Luo X, Wang J
Archives of biochemistry and biophysics 2022 Jun 15;722:109236
Archives of biochemistry and biophysics 2022 Jun 15;722:109236
Aldehyde dehydrogenase 2 deficiency promotes skeletal muscle atrophy in aged mice.
Kasai A, Jee E, Tamura Y, Kouzaki K, Kotani T, Nakazato K
American journal of physiology. Regulatory, integrative and comparative physiology 2022 Jun 1;322(6):R511-R525
American journal of physiology. Regulatory, integrative and comparative physiology 2022 Jun 1;322(6):R511-R525
Lactoferrin Prevents Chronic Alcoholic Injury by Regulating Redox Balance and Lipid Metabolism in Female C57BL/6J Mice.
Li DM, Wu YX, Hu ZQ, Wang TC, Zhang LL, Zhou Y, Tong X, Xu JY, Qin LQ
Antioxidants (Basel, Switzerland) 2022 Jul 31;11(8)
Antioxidants (Basel, Switzerland) 2022 Jul 31;11(8)
Effect of different types of muscle activity on the gene and protein expression of ALDH family members in C57BL/6J mouse skeletal muscle.
Jee E, Tamura Y, Kouzaki K, Kotani T, Nakazato K
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 2022 Jul 1;47(7):775-786
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 2022 Jul 1;47(7):775-786
The Anti-Adiposity Mechanisms of Ampelopsin and Vine Tea Extract in High Fat Diet and Alcohol-Induced Fatty Liver Mouse Models.
Wu J, Miyasaka K, Yamada W, Takeda S, Shimizu N, Shimoda H
Molecules (Basel, Switzerland) 2022 Jan 18;27(3)
Molecules (Basel, Switzerland) 2022 Jan 18;27(3)
Alda-1, an Activator of ALDH2, Improves Postresuscitation Cardiac and Neurological Outcomes by Inhibiting Pyroptosis in Swine.
Diao M, Xu J, Wang J, Zhang M, Wu C, Hu X, Zhu Y, Zhang M, Hu W
Neurochemical research 2022 Apr;47(4):1097-1109
Neurochemical research 2022 Apr;47(4):1097-1109
Aldehyde dehydrogenase 2 and PARP1 interaction modulates hepatic HDL biogenesis by LXRα-mediated ABCA1 expression.
Li L, Zhong S, Li R, Liang N, Zhang L, Xia S, Xu X, Chen X, Chen S, Tao Y, Yin H
JCI insight 2022 Apr 8;7(7)
JCI insight 2022 Apr 8;7(7)
Aldehyde Dehydrogenase 2 Protects Against Lipopolysaccharide-Induced Myocardial Injury by Suppressing Mitophagy.
Ji W, Wan T, Zhang F, Zhu X, Guo S, Mei X
Frontiers in pharmacology 2021;12:641058
Frontiers in pharmacology 2021;12:641058
ALDH2 is a prognostic biomarker and related with immune infiltrates in HCC.
Yao S, Yin X, Chen T, Chen W, Zuo H, Bi Z, Zhang X, Jing Y, Pang L, Cheng H
American journal of cancer research 2021;11(11):5319-5337
American journal of cancer research 2021;11(11):5319-5337
Daily Dose of Bovine Lactoferrin Prevents Ethanol-Induced Liver Injury and Death in Male Mice by Regulating Hepatic Alcohol Metabolism and Modulating Gut Microbiota.
Li D, He Q, Yang H, Du Y, Yu K, Yang J, Tong X, Guo Y, Xu J, Qin L
Molecular nutrition & food research 2021 Sep;65(18):e2100253
Molecular nutrition & food research 2021 Sep;65(18):e2100253
Transcriptional Silencing of ALDH2 Confers a Dependency on Fanconi Anemia Proteins in Acute Myeloid Leukemia.
Yang Z, Wu XS, Wei Y, Polyanskaya SA, Iyer SV, Jung M, Lach FP, Adelman ER, Klingbeil O, Milazzo JP, Kramer M, Demerdash OE, Chang K, Goodwin S, Hodges E, McCombie WR, Figueroa ME, Smogorzewska A, Vakoc CR
Cancer discovery 2021 Sep;11(9):2300-2315
Cancer discovery 2021 Sep;11(9):2300-2315
Trehalose activates hepatic transcription factor EB (TFEB) but fails to ameliorate alcohol-impaired TFEB and liver injury in mice.
Chao X, Wang S, Yang L, Ni HM, Ding WX
Alcoholism, clinical and experimental research 2021 Oct;45(10):1950-1964
Alcoholism, clinical and experimental research 2021 Oct;45(10):1950-1964
Low-Dose Pesticides Alter Primary Human Bone Marrow Mesenchymal Stem/Stromal Cells through ALDH2 Inhibition.
Foucault A, Ravalet N, Besombes J, Picou F, Gallay N, Babin L, Bourgeais J, Hamard S, Domenech J, Loyer P, Vallet N, Lejeune J, Gyan E, Béné MC, Vallette F, Olivier C, Hérault O
Cancers 2021 Nov 14;13(22)
Cancers 2021 Nov 14;13(22)
Aldehyde Dehydrogenase 2 Mediates Alcohol-Induced Colorectal Cancer Immune Escape through Stabilizing PD-L1 Expression.
Zhang H, Xia Y, Wang F, Luo M, Yang K, Liang S, An S, Wu S, Yang C, Chen D, Xu M, Cai M, To KKW, Fu L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 May;8(10):2003404
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 May;8(10):2003404
Acetaldehyde Dehydrogenase 2 regulates HMG-CoA reductase stability and cholesterol synthesis in the liver.
Zhong S, Li L, Liang N, Zhang L, Xu X, Chen S, Yin H
Redox biology 2021 May;41:101919
Redox biology 2021 May;41:101919
Analysis of disease model iPSCs derived from patients with a novel Fanconi anemia-like IBMFS ADH5/ALDH2 deficiency.
Mu A, Hira A, Niwa A, Osawa M, Yoshida K, Mori M, Okamoto Y, Inoue K, Kondo K, Kanemaki MT, Matsuda T, Ito E, Kojima S, Nakahata T, Ogawa S, Tanaka K, Matsuo K, Saito MK, Takata M
Blood 2021 Apr 15;137(15):2021-2032
Blood 2021 Apr 15;137(15):2021-2032
Pretreatment with the ALDH2 activator Alda‑1 protects rat livers from ischemia/reperfusion injury by inducing autophagy.
Liu Z, Ye S, Zhong X, Wang W, Lai CH, Yang W, Yue P, Luo J, Huang X, Zhong Z, Xiong Y, Fan X, Li L, Wang Y, Ye Q
Molecular medicine reports 2020 Sep;22(3):2373-2385
Molecular medicine reports 2020 Sep;22(3):2373-2385
Alda-1, an activator of ALDH2, ameliorates Achilles tendinopathy in cellular and mouse models.
Liu YC, Wang HL, Huang YZ, Weng YH, Chen RS, Tsai WC, Yeh TH, Lu CS, Chen YL, Lin YW, Chen YJ, Hsu CC, Chiu CH, Chiu CC
Biochemical pharmacology 2020 May;175:113919
Biochemical pharmacology 2020 May;175:113919
Combination of podophyllotoxin and rutin modulate radiation-induced alterations of jejunal proteome in mice.
Bajaj S, Alam SI, Ahmad B, Farooqi H, Gupta ML
International journal of radiation biology 2020 Jul;96(7):879-893
International journal of radiation biology 2020 Jul;96(7):879-893
Two Aldehyde Clearance Systems Are Essential to Prevent Lethal Formaldehyde Accumulation in Mice and Humans.
Dingler FA, Wang M, Mu A, Millington CL, Oberbeck N, Watcham S, Pontel LB, Kamimae-Lanning AN, Langevin F, Nadler C, Cordell RL, Monks PS, Yu R, Wilson NK, Hira A, Yoshida K, Mori M, Okamoto Y, Okuno Y, Muramatsu H, Shiraishi Y, Kobayashi M, Moriguchi T, Osumi T, Kato M, Miyano S, Ito E, Kojima S, Yabe H, Yabe M, Matsuo K, Ogawa S, Göttgens B, Hodskinson MRG, Takata M, Patel KJ
Molecular cell 2020 Dec 17;80(6):996-1012.e9
Molecular cell 2020 Dec 17;80(6):996-1012.e9
Aldehyde dehydrogenase 2 protects against sympathetic excitation-induced cardiac fibrosis.
Yuan Q, Yang F, Dai S, Wang Z, Xu Y, Xu BC, Sun Y, Zheng B, Zhao Y, Wang W, Liu B, Wang J, Cui S, Cao S, Zhang R, Xue L, Wei S, Xue M, Xu T, Xu F, Chen Y
Biochemical and biophysical research communications 2020 Dec 17;533(4):1427-1434
Biochemical and biophysical research communications 2020 Dec 17;533(4):1427-1434
Acetaldehyde dehydrogenase 2 deficiency increases mitochondrial reactive oxygen species emission and induces mitochondrial protease Omi/HtrA2 in skeletal muscle.
Wakabayashi Y, Tamura Y, Kouzaki K, Kikuchi N, Hiranuma K, Menuki K, Tajima T, Yamanaka Y, Sakai A, Nakayama KI, Kawamoto T, Kitagawa K, Nakazato K
American journal of physiology. Regulatory, integrative and comparative physiology 2020 Apr 1;318(4):R677-R690
American journal of physiology. Regulatory, integrative and comparative physiology 2020 Apr 1;318(4):R677-R690
Acetaldehyde dehydrogenase 2 interactions with LDLR and AMPK regulate foam cell formation.
Zhong S, Li L, Zhang YL, Zhang L, Lu J, Guo S, Liang N, Ge J, Zhu M, Tao Y, Wu YC, Yin H
The Journal of clinical investigation 2019 Jan 2;129(1):252-267
The Journal of clinical investigation 2019 Jan 2;129(1):252-267
Alda-1 Ameliorates Liver Ischemia-Reperfusion Injury by Activating Aldehyde Dehydrogenase 2 and Enhancing Autophagy in Mice.
Li M, Xu M, Li J, Chen L, Xu D, Tong Y, Zhang J, Wu H, Kong X, Xia Q
Journal of immunology research 2018;2018:9807139
Journal of immunology research 2018;2018:9807139
A comparison of CRISPR/Cas9 and siRNA-mediated ALDH2 gene silencing in human cell lines.
Wang F, Guo T, Jiang H, Li R, Wang T, Zeng N, Dong G, Zeng X, Li D, Xiao Y, Hu Q, Chen W, Xing X, Wang Q
Molecular genetics and genomics : MGG 2018 Jun;293(3):769-783
Molecular genetics and genomics : MGG 2018 Jun;293(3):769-783
Limitations of lymphoblastoid cell lines for functional analysis of SNPs.
Pathak H, Frieling H, Rhein M, Burkert A
BMC research notes 2017 Nov 2;10(1):548
BMC research notes 2017 Nov 2;10(1):548
Loss of NAD-Dependent Protein Deacetylase Sirtuin-2 Alters Mitochondrial Protein Acetylation and Dysregulates Mitophagy.
Liu G, Park SH, Imbesi M, Nathan WJ, Zou X, Zhu Y, Jiang H, Parisiadou L, Gius D
Antioxidants & redox signaling 2017 May 20;26(15):849-863
Antioxidants & redox signaling 2017 May 20;26(15):849-863
Alcohol Dehydrogenase 5 Is a Source of Formate for De Novo Purine Biosynthesis in HepG2 Cells.
Bae S, Chon J, Field MS, Stover PJ
The Journal of nutrition 2017 Apr;147(4):499-505
The Journal of nutrition 2017 Apr;147(4):499-505
Liver-Specific Deletion of Phosphatase and Tensin Homolog Deleted on Chromosome 10 Significantly Ameliorates Chronic EtOH-Induced Increases in Hepatocellular Damage.
Shearn CT, Orlicky DJ, McCullough RL, Jiang H, Maclean KN, Mercer KE, Stiles BL, Saba LM, Ronis MJ, Petersen DR
PloS one 2016;11(4):e0154152
PloS one 2016;11(4):e0154152
Activation of peroxisome proliferator-activated receptor α ameliorates perfluorododecanoic acid-induced production of reactive oxygen species in rat liver.
Liu H, Zhang H, Cui R, Guo X, Wang D, Dai J
Archives of toxicology 2016 Jun;90(6):1383-97
Archives of toxicology 2016 Jun;90(6):1383-97
Aldehyde dehydrogenase 2 inhibits inflammatory response and regulates atherosclerotic plaque.
Pan C, Xing JH, Zhang C, Zhang YM, Zhang LT, Wei SJ, Zhang MX, Wang XP, Yuan QH, Xue L, Wang JL, Cui ZQ, Zhang Y, Xu F, Chen YG
Oncotarget 2016 Jun 14;7(24):35562-35576
Oncotarget 2016 Jun 14;7(24):35562-35576
Quantitative proteomic analysis reveals that anti-cancer effects of selenium-binding protein 1 in vivo are associated with metabolic pathways.
Ying Q, Ansong E, Diamond AM, Lu Z, Yang W, Bie X
PloS one 2015;10(5):e0126285
PloS one 2015;10(5):e0126285
Protective role of ALDH2 against acetaldehyde-derived DNA damage in oesophageal squamous epithelium.
Amanuma Y, Ohashi S, Itatani Y, Tsurumaki M, Matsuda S, Kikuchi O, Nakai Y, Miyamoto S, Oyama T, Kawamoto T, Whelan KA, Nakagawa H, Chiba T, Matsuda T, Muto M
Scientific reports 2015 Sep 16;5:14142
Scientific reports 2015 Sep 16;5:14142
Maternal aldehyde elimination during pregnancy preserves the fetal genome.
Oberbeck N, Langevin F, King G, de Wind N, Crossan GP, Patel KJ
Molecular cell 2014 Sep 18;55(6):807-817
Molecular cell 2014 Sep 18;55(6):807-817
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse lung tissue were subjected to SDS PAGE followed by western blot with 15310-1-AP(ALDH2 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 15310-1-AP(ALDH2 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ALDH2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ALDH2. This antibody recognizes human,mouse,rat antigen. The ALDH2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.